An intracellular receptor recognizes a ligand inside a biological cell, including in the cytoplasm or cell nucleus. Some intracellular receptors regulate transcription after binding a membrane-permeable signal; an intracellular receptor does not universally imply direct control of DNA. See the receptor-location reference under receptor.
A ligand-regulated protein family whose members often act as DNA-binding regulators of transcription. Subcellular distribution and activation mechanisms vary between members.
A nuclear receptor responding to glucocorticoid ligands, with regulated localization and recruitment of transcriptional partners.
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