Fast ion-channel inactivation would reduce the outward potassium electric current just when it normally repolarizes the axon. Since , a reduction of positive makes the falling slope less negative. With other mechanisms unchanged, the action potential is generally broader and its after-hyperpolarization is weaker. A plateau or slow return is possible until sodium ion-channel inactivation, leakage, or another outward conductance restores the resting membrane potential. The precise trace depends on those remaining currents; rapid potassium inactivation alone does not determine a unique waveform.
Original schematic action potential broadening and two-state relaxation and sequential-transition probability densities
. Details. Articles by others on the same topic
There are currently no matching articles.
