A short RNA that guides sequence-specific silencing through an Argonaute protein; different pathways use different lengths and targets.
A class of Caenorhabditis elegans secondary small RNAs with a characteristic 5′ guanine and approximately 22-nucleotide length, generated by RNA-dependent RNA polymerases.
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Small interfering RNA (siRNA) is a class of double-stranded RNA molecules, typically about 20 to 25 base pairs in length, that play a crucial role in the process of RNA interference (RNAi). siRNA is involved in the regulation of gene expression and the defense against viral infections and transposable elements in cells.