Marie Curie by Ciro Santilli 37 Updated 2025-07-16
Like all big names in science, she was at the right place at the right time and with the right interest and passion.
Notably, the man she married, Pierre Curie, happened to be a the world master at precisely the technique that she needed to carefully measure radioactivity: he had the most precise electrometers in the world, which allowed to detect small amounts of radioactivity via the ionization of air by radiation . These used piezoelectricity, which Pierre Curie co-discovered with his brother.
Video 1.
Marie Curie section of The Mystery of Matter episode 2
. Source. Fantastic illustration of Marie's life and work!
Figure 1.
Marie Curie c. 1920
. Source.
DNA methylation by Ciro Santilli 37 Updated 2025-07-16
The first found and most important known epigenetic marker.
Happens only on adenine and cytosine. Adenine methylation is much less common in mammal than cytosine methylation, when people say "methylation" they often mean just cytosine methylation.
It often happens on promoters, where it inhibits transcription.
Analogous problem to the secondary structure of proteins. Likely a bit simpler due to the strong tendency for complementary pairs to bind.
The Suruga Trough is a deep-sea trench located off the coast of Shizuoka Prefecture in Japan. It is part of the Nankai Trough system and runs parallel to the Izu Peninsula. The trench reaches depths of approximately 2,500 meters (about 8,200 feet) and is primarily significant for geological and geophysical studies.
K. B. Reid is an author known for writing in the genres of romance and young adult fiction. One of her notable works is "The Love Hypothesis," a popular book that blends elements of romance with themes of personal growth and emotional exploration. Reid's writing often features relatable characters and engaging plots, which resonate with a wide audience.
"Radio 1's Live Lounge – Volume 2" is a compilation album released by BBC Radio 1, featuring various artists performing live covers and original songs. This series showcases popular musicians and bands as they put their unique spin on notable tracks, often blending genres and styles. The Live Lounge sessions are well-known for their intimate setting and the creative reinterpretations of songs.
The Internet Society (ISOC) is a global nonprofit organization founded in 1992. It aims to promote the open development, evolution, and use of the Internet for the benefit of all people throughout the world. The organization is composed of a diverse community of individuals, including: 1. **Members**: ISOC has individual and organizational members who support its mission and participate in its activities. Membership includes people from various backgrounds, including technologists, policymakers, educators, and internet enthusiasts.
In association football (soccer), a squad number is a unique number assigned to a player within a team for a particular season or competition. Each player on a team typically dons a specific number on their jersey, which not only helps identify them on the field but also holds significance in terms of tradition and player roles.
Pincherle polynomials are a class of polynomials that arise in the context of functional analysis and operator theory, particularly in the study of linear differential and difference equations. Named after the Italian mathematician Antonio Pincherle, these polynomials can be defined through certain recurrence relations or orthogonality properties. In a more specific context, Pincherle polynomials can be used to express solutions to certain classes of problems involving linear transformations or series expansions.
As of my last knowledge update in October 2023, Squaregraph is a tool designed for businesses and organizations to help visualize data and create high-quality graphics for reporting, presentations, or marketing. It often aims to make data analysis more accessible and engaging through various visualization techniques, such as graphs, charts, and infographics. Squaregraph typically offers features that allow users to analyze data, generate visual content, and customize layouts to suit specific branding or informational needs.
A Piping and Instrumentation Diagram (P&ID) is a detailed graphic representation of a process system, showing the piping, equipment, instrumentation, and control devices. P&IDs are used in various fields such as chemical, oil and gas, mechanical, and environmental engineering to design, build, and manage process plants. ### Key Components of a P&ID: 1. **Piping**: The physical pipes that transport fluids, gases, or slurries through the system.
Variance is a statistical measure that reflects the degree of spread or dispersion of a set of values around their mean (average). When considering the variance of the mean and predicted responses, it is helpful to differentiate between two concepts: the variance of the sample mean and the variance of predicted responses in the context of regression models. ### Variance of the Mean 1.
Fictitious forces, also known as pseudo forces or inertial forces, are apparent forces that arise in non-inertial reference frames—frames of reference that are accelerating or rotating. These forces are not the result of any physical interaction but are instead perceived due to the acceleration of the observer's frame of reference.
A pump dispenser is a mechanism used to dispense liquid products in a controlled manner. It typically consists of a pump mechanism, a nozzle or spout, and a container that holds the liquid. When the user presses down on the pump mechanism, it creates suction that draws liquid from the container and pushes it out through the nozzle.
Station P, officially known as Ocean Station P (OSP), is a significant oceanographic measurement site located in the North Pacific Ocean. Positioned approximately 50°N latitude and 145°W longitude, it is part of a long-term monitoring program established to study various oceanic and atmospheric phenomena. Station P is particularly noted for its role in measuring physical, chemical, and biological properties of the ocean.
A status message in instant messaging refers to a brief message or indicator that communicates a user's availability, mood, or current activity to their contacts. Typically, users can set a status message to let others know whether they are online, busy, away, or available for conversation. The status can be represented in various forms, including: 1. **Text**: A simple message indicating the user's current state, such as "Busy", "At work", "On vacation", or "Feeling happy".
Stefan Tyszkiewicz is a name that could refer to various individuals, as it is not widely recognized in popular culture or historical records up to October 2023. Without additional context, it's challenging to provide specific information.
"Soul Man" is an album by the American singer and musician Sam Moore, known for his powerful voice and contributions to the soul genre. Released in 1981, the album features Moore's interpretations of various soul and R&B classics, showcasing his distinctive vocal style. One of the most notable tracks on the album is the title song, "Soul Man," which originally became famous as a hit for the duo Sam & Dave in the 1960s.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact