All of them need a vacuum because you can't shoot elecrons through air, as mentioned at Video "50,000,000x Magnification by AlphaPhoenix (2022)".

Ciro Santilli is very happy to meet people with related interests, he really loves his like-minded online friends. Even if you don't have something a specific goal in mind for the contact, please just say hi.

To contact Ciro publicly about any general subject that is not covered in a more specific GitHub repository, including saying hi or suggestions about his website either:

For comments about China, first read:and then create a GitHub issue at: github.com/cirosantilli/china-dictatorship/issues/new

Publicly viewable contact is preferred if possible to more effectively share Ciro's wisdom with the world.

But if you feel more comfortable with private contact, no problem, either:

For other less good methods that will also likely work, use direct messages of the following profiles from under Section "Accounts controlled by Ciro Santilli":Ciro's Twitter DMs are also open, but note that Ciro receives endless Chinese language SPAM there which Twitter is doing nothing to combat, so it's not as reliable.

If you are a privacy freak or are going to tell Ciro state secrets Ciro has this GNU Privacy Guard public key: pubkey.gpg, but it's not something that he has ever really used.

Disqus comments were removed from his website in 2019-05-04, a manual dump is available here, removal rationale at: why Ciro Santilli removed Disqus comments from his website in 2019-05-04.

TEM: sample has to be very thin, you get a 2D image. Higher resolution possible.

SEM: sample does not need to be ultra thin, you get a 3D image. Lower resolution possible.

It sees and moves individual atoms!!!

This technique has managed to determine protein 3D structures for proteins that people were not able to crystallize for X-ray crystallography.

It is said however that cryoEM is even fiddlier than X-ray crystallography, so it is mostly attempted if crystallization attempts fail.

By looking at Figure 1. "A cryoEM image", you can easily understand the basics of cryoEM.

We just put a gazillion copies of our molecule of interest in a solution, and then image all of them in the frozen water.

Each one of them appears in the image in a random rotated view, so given enough of those point of view images, we can deduce the entire 3D structure of the molecule.

Ciro Santilli once watched a talk by Richard Henderson about cryoEM circa 2020, where he mentioned that he witnessed some students in the 1980's going to Germany, and coming into contact with early cryoEM. And when they came back, they just told their principal investigator: "I'm going to drop my PhD theme and focus exclusively on cryoEM". That's how hot the cryo thing was! So cool.

Main article: Section "Brain-computer interface".

This is one of the deep tech bets that Ciro Santilli would put his money in as of 2020.

How hard could it be? You just have to learn the encoding of the neural spine/eyes/ear, add an invasive device that multiplexes it, and then the benefits could be mind blowing.

Musk approves.

Interestingly and obviously, the initial advances in the area are happening for people that have hearing or vision difficulties. Since they already have a deficient sense, you don't lose that much by a failed attempt.

Hearing is likely to be the first since it feels the simplest. Ciro heard there are even already clinical applications there. TODO source.