Dynamic relaxation is a numerical method used primarily in structural analysis and computational mechanics to find static equilibrium of a system subjected to various forces. It is particularly useful for problems involving non-linear behavior or large deformations, where traditional static methods may struggle. The basic idea behind dynamic relaxation is to introduce an artificial dynamic behavior into the system. Instead of solving the equilibrium equations directly, the method treats the system as a dynamic one, allowing it to "relax" over time to reach a stable equilibrium position.
The Fast Multipole Method (FMM) is a numerical technique used to speed up the computation of interactions in systems with many particles, such as in simulations of gravitational, electrostatic, or other types of forces. The method was first introduced by Leslie Greengard and Vladimir Rokhlin in the late 1980s. ### Key Concepts of the Fast Multipole Method: 1. **Problem Context**: When simulating N-body problems (e.g.
The Hermes Project is a research initiative focused on the development of a high-performance, open-source JavaScript engine designed for running JavaScript applications on mobile devices. The primary aim of the project is to optimize JavaScript execution for React Native, a popular framework for building mobile applications using JavaScript and React. Key features of the Hermes Project include: 1. **Performance Optimization**: Hermes is designed to improve the start-up time and overall performance of applications.
The Jenkins–Traub algorithm is a numerical method used for finding the roots of polynomials. It is particularly effective for finding all the roots, including both real and complex roots, of a polynomial with real coefficients. The algorithm is notable for its efficiency and robustness. ### Key Features of Jenkins–Traub Algorithm: 1. **Root-Finding**: It finds all the roots of a polynomial in a systematic manner, starting from an initial guess and refining this guess iteratively.
In genetics, an isochore is a large, homogenous region of DNA that has a relatively uniform GC (guanine-cytosine) content. Isochores are characterized by their consistent nucleotide composition over a significant physical length, typically in the megabase range. This contrasts with more typical genomic regions, which can have varying GC content over shorter distances.
The term "nanodomain" can refer to different concepts depending on the context in which it is used. In general, it often relates to structures or regions at the nanoscale (typically between 1 and 100 nanometers) in various fields such as materials science, biology, and nanotechnology.
PDE7B, or Phosphodiesterase 7B, is an enzyme that is part of the phosphodiesterase (PDE) family. This family of enzymes plays a key role in regulating intracellular levels of cyclic nucleotides, specifically cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). PDE7B specifically hydrolyzes cAMP, leading to its degradation, which ultimately affects various signaling pathways within cells.
The P element, commonly referred to as phosphorus, is a chemical element with the symbol **P** and atomic number **15**. It is a non-metal that is essential for life and found in various forms. Here are some key points about phosphorus: 1. **Forms**: Phosphorus exists in several allotropes, including white phosphorus, red phosphorus, and black phosphorus. Each allotrope has distinct physical and chemical properties.
Pseudo-response regulators (PRRs) are a class of proteins involved in the regulation of circadian rhythms and other biochemical pathways in various organisms, including plants and microbes. They are part of a broader family known as response regulators, which are involved in two-component signaling systems. While traditional response regulators typically participate in signaling pathways that involve phosphorylation (a common post-translational modification that can activate or deactivate protein functions), PRRs function differently.
Rapid Amplification of cDNA Ends (RACE) is a molecular biology technique used to amplify the ends of a specific RNA molecule to obtain full-length complementary DNA (cDNA) sequences. This technique is particularly useful for identifying the 5' and 3' ends of mRNA transcripts, which can be important for understanding gene expression, alternative splicing, and RNA processing.
The ribosome-binding site (RBS) is a specific sequence in mRNA that is essential for the initiation of translation in prokaryotic organisms. It is typically located upstream of the start codon (AUG or other start codons) and plays a critical role in the proper positioning of the ribosome on the mRNA to ensure that protein synthesis begins correctly.
An SNP array, or Single Nucleotide Polymorphism array, is a powerful and widely used genomic tool designed to detect and analyze single nucleotide polymorphisms across a genome. SNPs are variations at a single base pair in the DNA sequence among individuals, and they can play significant roles in genetic diversity, disease susceptibility, and other biological processes.
Third-generation sequencing (TGS) refers to a set of advanced DNA sequencing technologies that enable the direct reading of nucleic acid sequences in a more rapid and cost-effective manner compared to earlier sequencing methods. Unlike first-generation (Sanger sequencing) and second-generation (next-generation sequencing, or NGS) techniques, third-generation sequencing allows for the sequencing of longer DNA fragments, which is particularly beneficial for resolving complex genomes, repetitive regions, and structural variants.
Trans-Spliced Exon Coupled RNA End Determination (TSEC-RNA-Seq) is a molecular biology technique used to analyze RNA molecules, particularly focusing on determining the ends of trans-spliced mRNA variants. This method is significant in studying gene expression, alternative splicing, and the diversity of RNA molecules in eukaryotic organisms.
Transcriptomics is the study of the complete set of RNA transcripts produced by the genome of an organism under specific circumstances or in a particular cell type. This area of research provides insights into gene expression, regulation, and the functional elements of the genome. Several technologies are used in transcriptomics to analyze RNA, each with its own strengths and applications.
Tre recombinase is an enzyme that belongs to the family of site-specific recombinases, which are proteins that catalyze the rearrangement of specific DNA sequences. Tre recombinase is derived from the bacteriophage T4 and is known for its ability to mediate the recombination of DNA sequences at defined sites. This enzyme recognizes specific DNA substrates, facilitating processes such as inversion, deletion, or integration of DNA segments.
A beer engine is a mechanical device used to pump beer from a cask to a tap, typically found in pubs and bars that serve real ale. It is designed to draw beer from a non-pressurized cask, allowing for the traditional serving of beer at a proper temperature and without the use of carbon dioxide or other gas pressures. The most common type of beer engine is a hand-pump, which requires the bartender to manually operate a lever to draw beer from the cask.
"Wetware" is a term that typically refers to the biological aspects of living systems, particularly in contrast to hardware (physical components) and software (programmatic components). In various fields, such as computing, biology, and neuroscience, wetware emphasizes the biological substrates and processes that enable complex functions. In computing, wetware is often used to describe the human brain and nervous system's functions as they relate to computing processes.
Jesús A. De Loera is a mathematician known for his work in various fields, including optimization, geometric combinatorics, and computational geometry. His research often involves topics related to the study of polytopes, convex geometry, and algorithms. He has published numerous papers and contributed to various mathematical communities.
John E. Dennis could refer to various individuals or entities, but without specific context, it’s hard to determine exactly which John E. Dennis you are asking about. He may be a notable figure in fields such as academia, business, or another area. If you have more details or context regarding who John E.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact