If it only it were written in JavaScript instead of Haskell (!?), then Ciro might have used it as the basis for OurBigBook Markup.
Journals must require source code and data sets to publish Updated 2025-07-11 +Created 1970-01-01
It is understandable that you might not be able to reproduce a paper that does a natural science experiment, given that physics is brutal.
But for papers that have either source code or data sets, academic journals must require that those be made available, or refuse to publish.
Any document without such obvious reproducibility elements is a white paper, not a proper peer reviewed paper.
Identification: kitronik.co.uk/blogs/resources/explore-micro-bit-v1-microbit-v2-differences The easiest thing is perhaps the GPIO notches.
Quantum mechanical re-interpretation of kinematic and mechanical relations by Heisenberg (1925) Updated 2025-07-11 +Created 1970-01-01
This Heisenberg's breakthrough paper on matrix mechanics which later led to the Schrödinger equation, see also: history of quantum mechanics.
Published on the Zeitschrift für Physik volume 33 page pages 879-893, link.springer.com/article/10.1007%2FBF01328377
Modern overview: www.mat.unimi.it/users/galgani/arch/heisenberg25amer_j_phys.pdf
Ciro Santilli with his soon-to-be Ciro Santilli's mother-in-law during his wedding in 2017
. A monopolistic operating system that only exists in the 2010's because of the IBM-linked historical lock-in and constant useless changes of the Microsoft Word document format to prevent cross operability.
It offers no technical advantages over free Linux distros in the late 2010's, and it is barely impossible to buy a non-Mac computer without paying for it, which should be illegal. European Union, time to use your regulatory powers.
The following anecdote illustrates Windows' pervasiveness. Ciro Santilli was once tutoring a high school student in Brazil, and decided to try and get her into programming. When the "Windows is not free" subject came up, the high school student was shocked: "I paid 100 dollars for this?". She never even knew it was there. To her, it was "just a computer".
Laws should really be passed forcing OEMs to allow you to not buy Microsoft Windows when buying a computer, European Union, why have you failed me in 2016??? en.wikipedia.org/wiki/Bundling_of_Microsoft_Windows
blog.zorinaq.com/i-contribute-to-the-windows-kernel-we-are-slower-than-other-oper/ I Contribute to the Windows Kernel. We Are Slower Than Other Operating Systems. Here Is Why. by Marc Bevand (2013) has some interesting remarks:
There's also little incentive to create changes in the first place. On linux-kernel, if you improve the performance of directory traversal by a consistent 5%, you're praised and thanked. Here, if you do that and you're not on the object manager team, then even if you do get your code past the Ob owners and into the tree, your own management doesn't care. Yes, making a massive improvement will get you noticed by senior people and could be a boon for your career, but the improvement has to be very large to attract that kind of attention.
www.lgcstandards-atcc.org/products/all/49896.aspx:
- £355.00 in 2019
- biosafety level: 2
Reproduction time: www.quora.com/unanswered/How-long-do-Mycoplasma-bacteria-take-to-reproduce-under-optimal-conditions
Has one of the smallest genomes known, and JCVI made a minimized strain with 473 genes: JCVI-syn3.0.
The reason why genitalium has such a small genome is that parasites tend to have smaller DNAs. So it must be highlighted that genitalium can only survive in highly enriched environments, it can't even make its own amino acids, which it normally obtains fromthe host cells! And because it cannot do cellular respiration, it very likely replicates slower than say E. Coli. It's easy to be small in such scenarios!
Power, Sex, Suicide by Nick Lane (2006) section "How to lose the cell wall without dying" page 184 has some related mentions puts it well very:
One group, the Mycoplasma, comprises mostly parasites, many of which live inside other cells. Mycoplasma cells are tiny, with very small genomes. M. genitalium, discovered in 1981, has the smallest known genome of any bacterial cell, encoding fewer than genes. Despite its simplicity, it ranks among the most common of sexually transmitted diseases, producing symptoms similar to Chlamydia infection. It is so small (less than a third of a micron in diameter, or an order of magnitude smaller than most bacteria) that it must normally be viewed under the electron microscope; and difficulties culturing it meant its significance was not appreciated until the important advances in gene sequencing in the early 1990s. Like Rickettsia, Mycoplasma have lost virtually all the genes required for making nucleotides, amino acids, and so forth. Unlike Rickettsia, however, Mycoplasma have also lost all the genes for oxygen respiration, or indeed any other form of membrane respiration: they have no cytochromes, and so must rely on fermentation for energy.
Downsides mentioned at youtu.be/PSDd3oHj548?t=293:
- too small to see on light microscope
- difficult to genetically manipulate. TODO why?
- less literature than E. Coli.
Data:
- www.ncbi.nlm.nih.gov/bioproject/97 contains genome, genes, proteins.
- www.genome.jp/kegg-bin/show_pathway?mge01100 all known pathways. TODO: numerical reaction coefficients? Which enzyimes mediate what? Appears to factor pathways across organisms, which is awesome.
Just add GDB Dashboard, and you're good to go.
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