React setups:
This can be used to detect if a given species of microorganism is present in a sample, and is therefore a widely used diagnostics technique to see if someone is infected with a virus.
You could of course do full DNA Sequencing to see everything that is there, but since it is as a more generic procedure, sequencing is more expensive and slow.
The alternative is to use a DNA amplification technique.
Can be seen as a cheap form of DNA sequencing that only test for a few hits. Some major applications:
- gene expression profiling
- single-nucleotide polymorphism: specificity is high enough to detect snips
Most of these are going to be Whole-genome sequencing of some model organism:en.wikipedia.org/wiki/Whole_genome_sequencing#History lists them all. Basically th big "firsts" all happened in the 1990s and early 2000s.
- 1975 by Sanger et al.: 5 kbp of the single-stranded bacteriophage ΦX174 using Sanger's radiolabelling method
- 1981 by Sanger et al.: 17 kbp of human mitochondrial DNA via Sanger method, known as the Cambridge Reference Sequence
- 2003: Human Genome Project (3 Gbp)
Searching for "H" for hydrogen leads to: physics.nist.gov/cgi-bin/ASD/lines1.pl?spectra=H&limits_type=0&low_w=&upp_w=&unit=1&submit=Retrieve+Data&de=0&format=0&line_out=0&en_unit=0&output=0&bibrefs=1&page_size=15&show_obs_wl=1&show_calc_wl=1&unc_out=1&order_out=0&max_low_enrg=&show_av=2&max_upp_enrg=&tsb_value=0&min_str=&A_out=0&intens_out=on&max_str=&allowed_out=1&forbid_out=1&min_accur=&min_intens=&conf_out=on&term_out=on&enrg_out=on&J_out=on
AKA how this GitHub page gets served under the domain: cirosantilli.com
Ciro only touches this very rarely, and always forgets and go into great pain whenever a change needs to done, so it is important to document it.
The last change was of 2019-07-07, when Ciro moved from the www subdomain www.cirosantilli.com to the APEX cirosantilli.com. A redirect is setup from the www subdomain to APEX.
GoDaddy DNS entries:
Type Name Value TTL
A @ 185.199.108.153 1 Hour
A @ 185.199.109.153 1 Hour
A @ 185.199.110.153 1 Hour
A @ 185.199.111.153 1 Hour
CNAME www cirosantilli.github.io 1 HourMoved cirosantilli.com to Porkbun 2022-02, unfortunatly records were not automatically updated and domain went down for a bit, upadded to new entries for IPv6 as well which are not documented by GitHub:
TYPE HOST ANSWER TTL PRIORITY OPTIONS
A cirosantilli.com 185.199.108.153 600
A cirosantilli.com 185.199.109.153 600
A cirosantilli.com 185.199.110.153 600
A cirosantilli.com 185.199.111.153 600
AAAA cirosantilli.com 2606:50c0:8000::153 600
AAAA cirosantilli.com 2606:50c0:8001::153 600
AAAA cirosantilli.com 2606:50c0:8002::153 600
AAAA cirosantilli.com 2606:50c0:8003::153 600
CNAME www.cirosantilli.com cirosantilli.github.io 600where the IPs are obtained from: help.github.com/en/articles/setting-up-an-apex-domain#configuring-a-records-with-your-dns-provider (archive).
- Custom domain:
cirosantilli.com - Enforce HTTPS: checked
And the CNAME file is tracked in this repository: CNAME.
Integer factorization algorithms better than Shor's algorithm Updated 2025-07-11 +Created 1970-01-01
- 2023 www.schneier.com/blog/archives/2023/01/breaking-rsa-with-a-quantum-computer.html comments on "Factoring integers with sublinear resources on a superconducting quantum processor” arxiv.org/pdf/2212.12372.pdf
A group of Chinese researchers have just published a paper claiming that they can—although they have not yet done so—break 2048-bit RSA. This is something to take seriously. It might not be correct, but it’s not obviously wrong.We have long known from Shor’s algorithm that factoring with a quantum computer is easy. But it takes a big quantum computer, on the orders of millions of qbits, to factor anything resembling the key sizes we use today. What the researchers have done is combine classical lattice reduction factoring techniques with a quantum approximate optimization algorithm. This means that they only need a quantum computer with 372 qbits, which is well within what’s possible today. (The IBM Osprey is a 433-qbit quantum computer, for example. Others are on their way as well.)
It is quite amazing to read through books such as The Supermen: The Story of Seymour Cray by Charles J. Murray (1997), as it makes you notice that earlier CPUs (all before the 70's) were not made with integrated circuits, but rather smaller pieces glued up on PCBs! E.g. the arithmetic logic unit was actually a discrete component at one point.
The reason for this can also be understood quite clearly by reading books such as Robert Noyce: The Man Behind the Microchip by Leslie Berlin (2006). The first integrated circuits were just too small for this. It was initially unimaginable that a CPU would fit in a single chip! Even just having a very small number of components on a chip was already revolutionary and enough to kick-start the industry. Just imagine how much money any level of integration saved in those early days for production, e.g. as opposed to manually soldering point-to-point constructions. Also the reliability, size an weight gains were amazing. In particular for military and spacial applications originally.
A briefing on semiconductors by Fairchild Semiconductor (1967)
Source. Uploaded by the Computer History Museum. There is value in tutorials written by early pioneers of the field, this is pure gold.
Shows:
- photomasks
- silicon ingots and wafer processing
Found through Google with no direct relation known to Ciro Santilli:
- en.wikipedia.org/wiki/Santilli: Wikipedia page of the glorious family, Santillis with their own Wikipedia page:
- Ruggero Santilli: "fringe science guy", by far dominates Google as of 2019. Created the respectable R.M. Santilli Foundation
- Ray Santilli made a fake 1995 alien autopsy movie, YouTube sample: www.youtube.com/watch?v=sVcaT2QnoDs
- Ivana Santilli: Canadian singer, pop-electric-chill: www.youtube.com/watch?v=hQRuVN0H8dM
- accounts on important websites
- github.com/santilli anonymous GitHub as of 2019
- santilli.com/ for rent by realnames.com/ (wiki page) as of 2019
- Also Brazilian and tech related like Ciro Santilli.
- www.youtube.com/user/TheOverthrowShow thepetesantillishow.com/ Pete Santilli, American Conservative news commentator show, makes Ciro cringe of boredom. At least he has a passion.
Possibly related variants:
- Santillo:
- Will Santillo who makes somewhat artistic porn photos. His website with several free demos: santillophotography.com/
- www.linkedin.com/in/ciro-santillo-2025a6ba/ a "Ciro Santillo", github.com/Ciruxx, also a programmer
- Santilly, a town in Saône-et-Loire department, France
- santilly.com/ redirects to www.pompes-funebres-santilly.com/fr/, a French funerary service
The key content previously on this page was moved to the following sections:
It was mind blowing when in 2022, after several years of selection, one of the 7 finalists was broken on a classical computer, not even in a quantum computer! news.ycombinator.com/item?id=30466063 | eprint.iacr.org/2022/214 Breaking Rainbow Takes a Weekend on a Laptop by Ward Beullens. Dude announced he had a break a few days before submission: twitter.com/WardBeullens/status/1492780462028300290 On Twitter. He's so young. Epic.
Edit: and then, after the third round, things were a bit unclear, so they made a fourth round with 4 choices out of the 7 from round 3, and in August 2022 one of the four was broken again on a classic CPU!!! OMG: arstechnica.com/information-technology/2022/08/sike-once-a-post-quantum-encryption-contender-is-koed-in-nist-smackdown/
The Eighth Day of Creation has a related quote:
In a conversation a few weeks earlier at the faculty club of the Massachusetts Institute of Technology, a couple of biologists had speculated whether Pauling, whose recent popular book on the benefits to health and sanity of massive doses of vitamin C was stacked in display near the entrance of the M.I.T. bookstore, was showing signs of what one of the men called "old scientist's disease" - which they defined as what happens to great men when they grow beyond the psychological reach of the salutary system by which scientists blow the whistle on one another's mistakes.
The Nobel Prize Winners With Crazy Theories by Qxir
. Source. Ubuntu 20.10 crash...:
exceptions:ERROR Unhandled Exception
Traceback (most recent call last):
File "/usr/bin/openshot-qt", line 11, in <module>
load_entry_point('openshot-qt==2.5.1', 'gui_scripts', 'openshot-qt')()
File "/usr/lib/python3/dist-packages/openshot_qt/launch.py", line 97, in main
app = OpenShotApp(argv)
File "/usr/lib/python3/dist-packages/openshot_qt/classes/app.py", line 218, in __init__
from windows.main_window import MainWindow
File "/usr/lib/python3/dist-packages/openshot_qt/windows/main_window.py", line 45, in <module>
from windows.views.timeline_webview import TimelineWebView
File "/usr/lib/python3/dist-packages/openshot_qt/windows/views/timeline_webview.py", line 42, in <module>
from PyQt5.QtWebKitWidgets import QWebView
ImportError: /usr/lib/x86_64-linux-gnu/libQt5Quick.so.5: undefined symbol: _ZN4QRhi10newSamplerEN11QRhiSampler6FilterES1_S1_NS0_11AddressModeES2_, version Qt_5_PRIVATE_APIThe Story of Light by Bell Labs (2015)
Source. Gives some ideas of the history of fiber optics. Features: Herwig Kogelnik.Fiber optics fundamentals by Shaoul Ezekiel
. Source. 2008 at MIT. Theory and demonstration.- youtu.be/0DCrIAxEv_Y?t=560:Terefore, the 1.5 micrometer window truly is the minimum.
- on smaller wavelengths, loss is due to Rayleigh scattering
- on longer wavelengths, loss is due to material absorption
Sets are unordered, but we can use them to create ordered objects, which are of fundamental importance. Notably, they are used in the definition of functions.
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