Children: Ion channels
TRPC1, or Transient Receptor Potential Cation Channel Subfamily C Member 1, is a protein that functions as a channel for the flow of cations, particularly calcium ions (Ca²⁺), across cell membranes. It is part of the TRP (Transient Receptor Potential) channel family, which is involved in various physiological processes, including sensory perception, such as taste, vision, and pain.
TRPC2, or "Transient Receptor Potential Channel 2," is a type of ion channel that is part of the TRP (Transient Receptor Potential) family of channels. It is primarily expressed in the sensory neurons of the olfactory system, specifically in the sensory cilia of olfactory neurons in certain mammalian species. TRPC2 plays a crucial role in the detection of pheromones and other chemical signals, contributing to the sense of smell.
TRPC3, or transient receptor potential cation channel subfamily C member 3, is a protein that functions as an ion channel in various types of cells. It is part of the TRP (transient receptor potential) channel family, which is known for its role in a wide array of physiological processes, including sensory perception, cellular signaling, and calcium influx.
TRPC4 stands for "Transient Receptor Potential Cation Channel, Subfamily C, Member 4." It is a gene that encodes a protein belonging to the TRP channel family, which is known to generate ion currents and play significant roles in various physiological processes. TRPC4 is primarily a calcium-permeable channel and is involved in several signaling pathways.
TRPC4AP (Transient Receptor Potential Cation Channel Subfamily C Member 4-associated Protein) is a protein that is associated with the TRPC4 ion channel, which is part of the transient receptor potential (TRP) channel family. TRP channels are known to play roles in various physiological processes, including sensing environmental stimuli, and are involved in the regulation of calcium ions in cells.
TRPC5 (Transient Receptor Potential Cation Channel Subfamily C Member 5) is a protein that functions as an ion channel, specifically part of the TRP (Transient Receptor Potential) channel family. These channels are involved in various physiological processes, including the sensation of touch, temperature, and pain, as well as other functions related to cell signaling. TRPC5 is primarily known for its role in mediating calcium (Ca²⁺) influx into cells when activated.
TRPC6, or Transient Receptor Potential Channel 6, is a protein that functions as an ion channel, which is a type of membrane protein that allows specific ions to pass through the cell membrane. TRPC6 is part of the TRP (Transient Receptor Potential) channel family, which is involved in various physiological processes, including sensory perception, muscle contraction, and the regulation of cell signaling pathways.
TRPC7, or Transient Receptor Potential Cation Channel Subfamily P Member 7, is a protein that in humans is encoded by the TRPC7 gene. It is part of a larger family of transient receptor potential (TRP) channels, which are involved in various physiological processes, including sensory perception, signal transduction, and regulation of cellular calcium levels.
TRPM stands for Transient Receptor Potential Melastatin, which is a subfamily of the TRP (Transient Receptor Potential) channel family. TRPM channels are involved in various physiological processes, including the sensation of pain, temperature, and various cellular functions. TRPM channels, such as TRPM1, TRPM2, TRPM3, TRPM4, and TRPM8, are expressed in various tissues and have different roles.
TRPM1 (Transient Receptor Potential Melastatin 1) is a member of the TRP (transient receptor potential) ion channel family. It is primarily known for its role in sensory reception, particularly in the context of vision and pain. TRPM1 is expressed in various tissues, including the retina, where it is localized in the photoreceptor cells, specifically in the ON-bipolar cells.
TRPM2 (Transient Receptor Potential Melastatin 2) is a member of the TRP (Transient Receptor Potential) ion channel family, which is known for its role in various physiological processes, including the sensation of temperature, pain, and other stimuli.
TRPM3 (Transient Receptor Potential Melastatin 3) is a member of the transient receptor potential (TRP) channel family, which consists of ion channels that play critical roles in various physiological processes. Specifically, TRPM3 is known for its involvement in sensory transduction, particularly in the perception of pain and temperature.
TRPM4 (Transient Receptor Potential Melastatin 4) is a protein that functions as a channel for cations, particularly sodium and calcium ions, across cellular membranes. It is part of the TRP (Transient Receptor Potential) channel family, which is involved in various physiological processes, including sensory perception, temperature regulation, and ion homeostasis. TRPM4 is primarily known for its role in maintaining cell membrane potential and regulating cell excitability.
TRPM5 (Transient Receptor Potential Melastatin 5) is a member of the TRP (transient receptor potential) ion channel family. It is primarily expressed in certain sensory cells, particularly those involved in taste and in the inner ear. TRPM5 is a calcium-permeable cation channel that is activated by variations in intracellular calcium levels and is known to play a significant role in signal transduction processes.
TRPM6 (Transient Receptor Potential Melastatin 6) is a protein that functions as a channel for transporting ions across cell membranes. It is a member of the TRP (Transient Receptor Potential) channel family, specifically the melastatin subfamily. TRPM6 is primarily known for its role in magnesium homeostasis within the body. The protein is expressed in various tissues, including the kidneys and intestines, where it is crucial for the absorption of magnesium from the diet.
TRPM7 (Transient Receptor Potential Melastatin 7) is a member of the transient receptor potential (TRP) channel family, specifically belonging to the TRPM subfamily. It is a unique ion channel that combines properties of ion transport with those of a serine/threonine kinase, which means it has both ion channel and enzymatic functions. **Key Characteristics of TRPM7:** 1.
TRPM8 (Transient Receptor Potential Melastatin 8) is a member of the transient receptor potential (TRP) ion channel family, specifically categorized within the TRPM subfamily. It is a cation channel that is primarily responsive to cold temperatures and menthol, a cooling compound found in mint. TRPM8 plays a significant role in thermosensation, allowing the perception of coldness and cooling sensations.
TRPML, or "transient receptor potential mucolipin," refers to a family of ion channels that are part of the larger transient receptor potential (TRP) channel superfamily. The most well-known member of this family is TRPML1, which is primarily expressed in the cell membranes of various tissues, including the brain, heart, and kidney.
TRPN, or Transient Receptor Potential N-Methyl-D-Aspartate (NMDA) receptor Potentiating Protein, is a protein that is part of a family of transient receptor potential (TRP) channels. These channels are known for their role in various physiological processes, including sensory perception, pain, and thermoregulation. In the context of TRPN channels, they are involved in various cellular signaling pathways and can respond to different stimuli, such as temperature changes.
TRPP, or Transient Receptor Potential Polycystin, refers to a family of ion channels that play significant roles in various physiological processes. The two most notable members of this family are TRPP1 and TRPP2, which are integral to the function of the primary cilia in renal epithelial cells.