Children: Ion channels
KCNA2 (Potassium Voltage-Gated Channel Subfamily A Member 2) is a gene that encodes a protein known as a voltage-gated potassium channel. These channels play a crucial role in maintaining the electrical excitability of cells, particularly in neurons and muscle cells. The KCNA2 protein is involved in repolarizing the membrane potential after an action potential, helping to regulate the flow of potassium ions across the cell membrane.
KCNA3 (Potassium Voltage-Gated Channel Subfamily A Member 3) is a gene that encodes a protein that is part of the voltage-gated potassium channel family. These channels play a crucial role in maintaining the electrical excitability of cells by regulating the flow of potassium ions across cell membranes. KCNA3 is particularly involved in neuronal function and has been studied for its role in various physiological processes, including the repolarization phase of action potentials in neurons.
KCNA4 refers to the gene that encodes the potassium voltage-gated channel subfamily A member 4, which is a protein involved in the formation of ion channels that regulate the flow of potassium ions across cell membranes. This protein is significant in various physiological processes, including muscle contraction, neuronal signaling, and the maintenance of the resting membrane potential in cells.
KCNA5 is a gene that encodes a member of the voltage-gated potassium channel family. Specifically, KCNA5 codes for the alpha subunit of the potassium ion channel, which plays a crucial role in setting and regulating the membrane potential of cells, particularly in excitable tissues such as the heart and the nervous system.
KCNA6, or Potassium Voltage-Gated Channel Subfamily A Member 6, is a gene that encodes a protein that is part of the voltage-gated potassium channels. These channels play a crucial role in generating and regulating the electrical signals in neurons and muscle cells. Specifically, KCNA6 is associated with the rapid repolarization phase of action potentials, which is essential for proper nerve impulse transmission and muscle contraction.
KCNA7 is a gene that encodes a member of the potassium channel family. Specifically, it is known as "Potassium Voltage-Gated Channel Subfamily A Member 7." This protein plays a critical role in regulating the flow of potassium ions across cell membranes, which is essential for maintaining the electrical excitability of cells, particularly in the nervous system and muscle tissues.
KCNAB1 is a gene that encodes the potassium voltage-gated channel subfamily A member 1, which is a protein involved in the formation of ion channels in cell membranes. This protein plays a critical role in the physiological function of neurons and muscle cells by helping to regulate potassium ion (K+) flow across the cell membrane, which is essential for maintaining the resting membrane potential and facilitating action potentials.
KCNAB2, or Potassium Channel Subfamily A Regulatory Beta Subunit 2, is a protein that is part of the larger family of potassium channel proteins. Specifically, it encodes a regulatory subunit that interacts with certain types of potassium channels, influencing their function and properties. Potassium channels play crucial roles in various physiological processes, including the regulation of membrane potential, electrical excitability of cells, and neurotransmitter release.
KCNAB3 refers to a gene that encodes a protein called potassium voltage-gated channel subfamily A member 3. This protein is a part of the larger family of potassium channels, which are critical for various physiological processes, including the regulation of cardiac, neuronal, and muscle excitability. The KCNAB3 protein functions as an auxiliary subunit that can influence the properties of voltage-gated potassium channels, such as their conductance, kinetics, and membrane localization.
KCNB1 refers to a gene that encodes the potassium voltage-gated channel subfamily B member 1 protein. This protein is part of a family of potassium channels that are important for maintaining the resting membrane potential and modulating the excitability of neurons and other excitable tissues. The KCNB1 gene is located on chromosome 20 in humans and plays a crucial role in the cardiac and neural functions of the body.
KCNB2 is a gene that encodes a protein that is part of the voltage-gated potassium channel family. Specifically, KCNB2 codes for the K_v2.2 protein, which is a voltage-dependent potassium channel that plays a critical role in regulating membrane potential and contributing to the electrical excitability of neurons and other types of cells.
KCNC2, or Potassium Voltage-Gated Channel Subfamily C Member 2, is a gene that encodes a protein which is part of the voltage-gated potassium channel family. These channels are crucial for the regulation of electrical excitability in various types of cells, including neurons and muscle cells. They play a key role in establishing the resting membrane potential and repolarizing the action potentials of excitable cells.
KCNC3 (Potassium Voltage-Gated Channel Subfamily C Member 3) is a gene that encodes a protein involved in the functioning of potassium channels in mammalian cells. These channels are essential for a variety of physiological processes, including the regulation of membrane potential, neurotransmitter release, and the excitability of neurons and muscle cells.
KCNC4, or "Potassium voltage-gated channel subfamily C member 4," is a protein encoded by the KCNC4 gene in humans. This gene is part of a family of potassium ion channels, which are essential for various physiological processes, including the regulation of neuronal excitability, muscle contraction, and heart rhythm.
KCND1 is a gene that encodes a protein known as potassium voltage-gated channel subfamily D member 1. This protein is part of the voltage-gated potassium channels, which are important for the regulation of electrical activity in neurons and other excitable cells. The KCND1 protein contributes to the repolarization phase of the action potential in nerve and muscle cells, allowing these cells to return to their resting potential after being activated.
KCNE2 is a gene that encodes a protein known as the potassium voltage-gated channel subfamily E member 2. This protein is part of the potassium ion channel family, which plays a critical role in the electrophysiological properties of cells, particularly in the heart and nervous system. KCNE2 functions as a regulatory subunit for specific K+ channels, influencing their conductivity and gating properties.
KCNE4 is a gene that encodes a protein belonging to the KCNE family of potassium channel accessory subunits. These proteins are known to modulate the function of voltage-gated potassium channels, influencing their gating properties, conductance, and localization. Specifically, KCNE4 is associated with the modulation of ion flow and plays a role in various physiological processes, including the regulation of cardiac rhythm and other electrical activities in cells.
KCNE5, also known as potassium voltage-gated channel subfamily E member 5, is a gene that encodes a protein belonging to the KCNE family of potassium channel regulatory subunits. These subunits are crucial for the proper functioning of potassium channels, which play essential roles in various physiological processes, including the generation and propagation of electrical signals in excitable cells such as neurons and cardiac myocytes.
KCNF1, or "Potassium voltage-gated channel subfamily F member 1," is a gene that encodes a protein that forms a potassium ion channel in cell membranes. These channels play a crucial role in the electrical excitability of cells, including neurons and muscle cells, by controlling the flow of potassium ions (K+) across the cell membrane, which is essential for various physiological processes such as maintaining resting membrane potential, repolarization of action potentials, and overall cellular signaling.
KCNG1 (potassium voltage-gated channel subfamily G member 1) is a gene that encodes a protein involved in the formation of voltage-gated potassium channels. These channels are essential for the proper functioning of electrical signaling in neurons and muscle cells. The KCNG1 protein specifically contributes to the regulation of membrane potential and the excitability of cells.