Children: Ion channels
KCNG2, or Potassium Voltage-Gated Channel Subfamily G Member 2, is a gene that encodes a protein belonging to the family of voltage-gated potassium channels. These channels play crucial roles in various physiological processes by controlling the flow of potassium ions across cell membranes, which is vital for regulating the electrical excitability of neurons and muscle cells.
KCNG3, or potassium voltage-gated channel subfamily G member 3, is a gene that encodes a protein involved in the formation of potassium ion channels in the cell membrane. These channels play a critical role in the regulation of cellular excitability, which is important for various physiological processes, including neuronal signaling, muscle contraction, and cardiac function.
KCNG4, or "Potassium Voltage-Gated Channel Subfamily G Member 4," is a gene that encodes a protein belonging to the family of voltage-gated potassium channels. These channels are essential for the regulation of electrical signaling in tissues, particularly in the nervous system and muscle tissues. KCNG4 is specifically known for its role in the transmission of electrical impulses across cell membranes.
KCNH3 is a gene that encodes a protein belonging to the family of voltage-gated potassium channels. These channels are critical for the repolarization phase of action potentials in neurons and other excitable cells, playing a vital role in maintaining the electrical activity of cells, regulating heart rhythms, and contributing to various physiological processes. The KCNH3 protein is particularly associated with the regulation of neuronal excitability and has been implicated in certain neurological functions.
KCNH4 is a gene that encodes a protein known as a potassium channel, specifically a member of the voltage-gated potassium channel family. This family of channels is crucial for the regulation of electrical excitability in various tissues, including the heart and the nervous system. The KCNH4 protein functions by allowing potassium ions to flow across cell membranes in response to voltage changes, which plays a vital role in repolarizing the membrane potential after an action potential.
KCNH6, also known as potassium voltage-gated channel subfamily H member 6, is a gene that encodes a protein belonging to the family of voltage-gated potassium channels. These channels are crucial for the regulation of electrical excitability in various types of cells, particularly in neurons and muscle cells.
KCNH7 is a gene that encodes a member of the potassium voltage-gated channel family, specifically the KCNH (potassium channel subfamily H) group. These channels play crucial roles in various physiological processes by regulating the flow of potassium ions across cell membranes, which is essential for maintaining cellular excitability and signaling.
KCNH8 is a gene that encodes a protein belonging to the potassium channel family, specifically to the voltage-gated potassium channel subfamily H. These proteins are involved in various physiological processes by facilitating the flow of potassium ions across the cell membrane, which helps regulate electrical activity in cells, including neurons and muscle cells. The KCNH8 protein is believed to play a role in the repolarization phase of action potentials, essential for maintaining the normal electrical activity of cells.
KCNIP1, also known as K-channel interacting protein 1, is a gene that encodes a protein involved in the modulation of voltage-gated potassium channels. This protein is thought to play a crucial role in the regulation of neuronal excitability and synaptic transmission. KCNIP1 is particularly expressed in the brain and is believed to interact with various potassium channel subunits, thereby influencing their activity and potentially impacting various physiological processes, including learning and memory.
KCNIP4, also known as KCNIP4 (potassium voltage-gated channel interacting protein 4), is a protein that is part of the KCNIP family, which includes various regulatory proteins that interact with voltage-gated potassium channels. These proteins play an important role in modulating the activity of ion channels, affecting various physiological processes such as neuronal excitability, muscle contraction, and cardiac function.
KCNJ10 is a gene that encodes a member of the potassium ion channel family, specifically an inward-rectifier potassium channel. The protein produced by this gene is involved in potassium ion transport across cell membranes, which is crucial for various physiological processes, including maintaining the resting membrane potential of cells, regulating cellular excitability, and influencing the secretion of hormones and neurotransmitters.
KCNJ12, also known as potassium ion channel, subfamily J, member 12, is a gene that encodes a protein involved in the formation of potassium channels. These channels are integral to various cellular processes, including the regulation of cellular excitability, which is critical for proper function in tissues like the heart and nervous system.
KCNJ13 is a gene that encodes a protein known as a potassium ion channel. This protein is part of the inward rectifier potassium channel family. KCNJ13 is primarily expressed in retinal tissues and plays a crucial role in maintaining the electrochemical gradient across cell membranes, which is vital for various cellular functions including the regulation of electrical activity in neurons and cardiac cells.
KCNJ14, also known as the potassium voltage-gated channel subfamily J member 14, is a gene that encodes a protein that is part of the inwardly rectifying potassium channel family. These channels are essential for maintaining the resting membrane potential of cells and play significant roles in various physiological processes, including cardiac and neuronal excitability.
KCNJ15 is a gene that encodes a member of the potassium channel family, specifically belonging to the inwardly rectifying potassium (KIR) channels. These channels are integral membrane proteins that play a critical role in regulating the cell's membrane potential and, consequently, various physiological processes, including the regulation of heart rhythm, muscle contraction, and neuronal excitability. In particular, KCNJ15 is involved in the regulation of potassium ions (K+) across the cell membrane.
KCNJ16 is a gene that encodes a protein belonging to the potassium channel family, specifically the inwardly rectifying potassium channels. These channels play a critical role in maintaining the resting membrane potential of cells, regulating cellular excitability, and contributing to various physiological processes such as muscle contraction and neurotransmitter release. The KCNJ16 protein is encoded in humans and is known to be involved in the regulation of potassium ion flow across cell membranes.
KCNJ3 is a gene that encodes a protein known as potassium channel subfamily J member 3, which is a part of the inwardly rectifying potassium channels (Kir channels). These channels play a critical role in regulating the flow of potassium ions across cell membranes, which is essential for maintaining the resting membrane potential and overall excitability of cells, including neurons and cardiac cells.
KCNJ5 is a gene that encodes a protein belonging to the potassium ion channel family. Specifically, it encodes for the inwardly rectifying potassium channel 5 (Kir5.1). This protein plays a crucial role in various physiological processes by allowing potassium ions to flow in and out of cells, which is essential for maintaining the electrical stability of cell membranes and regulating cellular excitability. KCNJ5 is expressed in several tissues, including the adrenal glands, heart, and brain.
KCNJ6, also known as the potassium voltage-gated channel subfamily J member 6, is a gene that encodes a protein belonging to the inward rectifier potassium channel family. This family of channels is important for maintaining the resting membrane potential and regulating cellular excitability in various tissues, including the heart and brain. KCNJ6 is also known as the Kir3.
KCNJ8 is a gene that encodes a protein known as the potassium ion channel, specifically the K(ATP) channel, which is sensitive to intracellular ATP levels. This channel plays a crucial role in regulating cellular excitability, particularly in muscle and neuronal tissues. KCNJ8 is part of the inwardly rectifying potassium channel family and is typically associated with controlling various physiological processes, including insulin secretion in pancreatic beta cells, vascular smooth muscle contraction, and cardiac action potentials.