Children: Ion channels
KCNN1, or potassium calcium-activated channel subfamily N member 1, is a gene that encodes a protein involved in the regulation of ion channels in mammalian cells. The KCNN1 protein plays a role in the modulation of potassium ion (K+) currents and is part of a group of channels known as the potassium calcium-activated channels (also known as SK channels or small conductance calcium-activated potassium channels).
KCNN2, or "Potassium Calcium-Activated Channel Subfamily N Member 2," is a gene that encodes a protein belonging to the SK (small-conductance Ca^2+-activated K^+) channel family. These channels play a vital role in regulating neuronal excitability and smooth muscle contraction by allowing potassium ions to flow out of cells in response to increases in intracellular calcium levels.
KCNN4, also known as the potassium voltage-gated channel subfamily N member 4, is a gene that encodes a protein belonging to a family of ion channels. These types of ion channels are involved in various physiological processes, including the regulation of electrical activity in neurons and muscle cells, as well as modulation of various hormonal and neurotransmitter responses. KCNN4 specifically encodes a calcium-activated potassium channel, which means that its activity is stimulated by the presence of calcium ions.
KCNQ4 is a gene that encodes a potassium ion channel, which is part of the KCNQ (Kv7) family of voltage-gated potassium channels. These channels are important for the regulation of electrical activity in various tissues, particularly in the nervous system and the inner ear. KCNQ4 specifically plays a critical role in the auditory system, where it helps to control the membrane potential of hair cells in the cochlea.
KCNQ5 is a gene that encodes a member of the potassium voltage-gated channel subfamily Q. The channels formed by KCNQ5 are involved in various physiological processes, including regulating the excitability of neurons and other types of cells. This specific potassium channel is known to contribute to the M-current, which is a slow, voltage-gated potassium current that helps stabilize the membrane potential and can influence the firing patterns of action potentials in neurons.
KCNQ channels, also known as M-type potassium channels, are a family of voltage-gated potassium channels that are encoded by the KCNQ gene family. These channels play a crucial role in regulating neuronal excitability and are important for setting the resting membrane potential and shaping action potentials in neurons and other excitable cells.
KCNS1 (potassium voltage-gated channel subfamily S member 1) is a gene that encodes a protein belonging to the voltage-gated potassium channel family. These channels play a crucial role in various physiological processes by contributing to the regulation of membrane potential and electrical excitability in neurons and muscle cells.
KCNS2 is a gene that encodes a type of potassium channel known as a voltage-gated potassium channel. Specifically, the protein produced by this gene is known as the potassium voltage-gated channel subfamily S member 2. These channels play a crucial role in maintaining the electrical potential across the cell membrane and are involved in various physiological processes, including the regulation of neuronal excitability, muscle contraction, and cardiac rhythm.
KCNS3, or "Potassium Voltage-Gated Channel Subfamily S Member 3," is a gene that encodes a protein belonging to the family of voltage-gated potassium channels. These channels are integral membrane proteins that play a crucial role in the electrical activity of neurons and muscle cells by allowing the flow of potassium ions across the cell membrane.
KCNT1 is a gene that encodes a type of potassium ion channel, specifically a member of the Slo-related (also known as K_Ca or K-channel) family of potassium channels. These channels play critical roles in regulating various physiological processes, including neuronal excitability, muscle contraction, and the cardiac action potential.
KCNT2 (Potassium Channel, Subfamily T, Member 2) is a gene that encodes a protein contributing to the formation of ion channels in the cell membranes. These channels are regulated by potassium ions (K+), which are essential for a variety of physiological functions, including the regulation of cell excitability, electrical signaling in neurons, and muscle contraction.
KCNV1 is a gene that codes for a protein known as "KCNV1 potassium voltage-gated channel, subfamily V, member 1." This protein is part of the voltage-gated potassium channel family, which plays a crucial role in the electrical properties of cells, especially in the nervous system. KCNV1 is particularly important in the retina and is involved in the regulation of the neuronal excitability of photoreceptor cells.
KCNV2 is a gene that encodes a potassium voltage-gated channel subunit. Potassium channels are essential for various physiological processes, including the regulation of electrical activity in neurons and muscle cells. The KCNV2 protein is specifically involved in the formation of voltage-gated potassium channels that contribute to the repolarization phase of action potentials in excitable tissues.
KcsA is a potassium ion (K⁺) channel derived from the bacterium *Streptomyces lividans*. It is one of the first potassium channels to be structurally characterized, providing significant insights into the mechanism of ion selectivity and channel function in biological systems. KcsA is a homotetrameric protein, meaning it is composed of four identical subunits that together form a central pore through which potassium ions can pass.
Kir2.1, also known as KCNJ2, is a member of the inwardly rectifying potassium (Kir) channel family. These channels play a crucial role in regulating the resting membrane potential of cells, contributing to various physiological processes, including the regulation of heart rate, neuronal excitability, and smooth muscle contraction. Here are some key points about Kir2.1: 1. **Structure**: Kir2.
Kir2.6, also known as KCNJ18, is a member of the inwardly rectifying potassium channel (KIR) family. Inwardly rectifying potassium channels play a crucial role in maintaining the resting membrane potential and regulating cellular excitability by allowing potassium ions (K+) to flow into cells more easily than they can flow out. This property is essential for various physiological processes, including regulating heart rhythm, neuronal firing, and smooth muscle contraction. Kir2.
Kir6.2 is a subunit of the ATP-sensitive potassium (K_ATP) channels, which are crucial for various physiological processes, including the regulation of insulin secretion in pancreatic beta cells, muscle excitability, and neuronal activity. K_ATP channels are formed by the assembly of two types of subunits: the Kir6.x subunits (where 'x' can be 1 or 2) and the SUR (sulfonylurea receptor) subunits. Kir6.
Kv1.1 refers to a specific type of voltage-gated potassium channel that is encoded by the KCNA1 gene in humans. These channels play a crucial role in regulating membrane potentials and excitability in neurons and other cell types by allowing potassium ions to flow out of the cell in response to changes in membrane voltage. The Kv1.
KvLQT1, also known as KCNQ1, is a potassium ion channel encoded by the KCNQ1 gene in humans. It is part of the voltage-gated potassium channel family and plays a crucial role in cardiac and various other physiological processes. The KvLQT1 channel is integral to the repolarization phase of the cardiac action potential, meaning it helps return the heart muscle cells to their resting state after contraction.
KvLQT2, also known as KCNQ1, is a gene that encodes a protein which is part of the voltage-gated potassium channel family. This channel is crucial for the conduction of potassium ions across cell membranes and plays an important role in repolarizing the cardiac action potential, which is essential for maintaining the heart's rhythm.