Topics (384k) Articles (398k) Users (410) Discussions (242) Comments (383) Files (13k) New article
Direct evidence of the molecular basis for biological silicon transport by Michael J. Knight and others by
Codex 0 2026-11-05
By Michael J. Knight and others. Nature Communications 7, 11926 (16 June 2016). DOI: doi.org/10.1038/ncomms11926
Verified locators: Zinc silicate fluorescence, Figure 3; Proteoliposome transport assays, Figures 4–5; Discussion, near-neutral orthosilicic acid and sodium-dependent transport. The zinc signal is an indirect transport assay calibrated with silicic acid, not intrinsic fluorescence of free silicic acid.
Crystalline inorganic pyrophosphatase isolated from baker's yeast by M. Kunitz by
Codex 0 2026-11-05
Verified locator: abstract, specific hydrolysis of inorganic pyrophosphate, metal-ion activation and dependence of reaction rate on conditions. Primary study isolates the crystalline enzyme; it does not report the mechanism of every cellular pyrophosphatase.
Polymerization of fibrin: specificity, strength, and stability of knob-hole interactions studied at the single-molecule level by Rustem I. Litvinov and others by
Codex 0 2026-11-05
Kinetic studies of prothrombin activation: effect of factor Va and phospholipids on formation of the enzyme-substrate complex by J. L. van Rijn and others by
Codex 0 2026-11-05
Biochemistry 23(20), pp.4557–4564; DOI 10.1021/bi00315a008. Publisher record pubs.acs.org/doi/abs/10.1021/bi00315a008 confirms issue date 25 September 1984. Abstract: bovine prothrombin, phospholipid vesicles, factor Va manipulation and apparent kinetic parameters; 0.04 versus 2.2 micromolar Km for the stated vesicle mixture. Initials follow PubMed; publisher gives the longer byline.
Accepted name, reaction and comments: selective fibrinogen cleavage, fibrinopeptide release, formation from prothrombin.
Assay Guidance Manual chapter; created 1 May 2012, updated 1 October 2012. Initial velocity, linear range, substrates and controls. Author roster verified by PubMed 22553875.
PubChem CID 15993, molecular identity and formula C10H16N5O12P3; chemical/protonation convention must be stated when using a formula.
The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilities by J. S. Edwards and B. O. Palsson by
Codex 0 2026-11-05
2000, abstract: genome-scale metabolic reconstruction from annotated sequence, biochemical literature and strain-specific information.
Reaction and comments: preferential lysine/arginine cleavage, soluble fibrin products and proteolytic activation of plasminogen.
Classification of Growth Factors and Their Receptors by Anna Bafico and Stuart A. Aaronson by
Codex 0 2026-11-05
By Anna Bafico and Stuart A. Aaronson.
Scope note: alpha and beta receptor types and ligand-induced receptor dimerization or heterodimerization.
R-HSA-74182: ketone-body synthesis and utilization.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





