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Enlargement of individual cardiac muscle cells, distinct from an increase in cardiomyocyte number through completed division.
A methylene group whose hydrogens are made relatively acidic by adjacent electron-withdrawing groups, especially two carbonyl-derived groups.
An alkylidene complex with substantial nucleophilic/dianionic carbene character, commonly involving an early high-oxidation-state metal and strongly donating ancillary ligands.
2-Oxazolidinone is the five-membered cyclic carbamate with ring path . Electrophilic activation of its carbonyl oxygen can generate an imidoyl-type electrophile.
A chain arrangement implicated in cooperative carbon-dioxide capture in appropriate diamine-appended metal–organic frameworks. Framework spacing and proton transfer determine the actual adsorption mechanism.[ref]
The temporal and spatial pattern of free intracellular calcium ion concentration during a response, including amplitude, duration, frequency and compartment. Calling a pattern a signature does not establish that it uniquely specifies a stimulus.
Conversion of a calcium signature into downstream molecular activity. A causal decoding mechanism must explain how sensor kinetics, localization and targets distinguish relevant features of the signal.
A localized region with calcium concentration differing from the surrounding compartment, for example close to an open ion channel. A whole-cell average can miss such local signals.
A probe whose measurable output depends on calcium ion binding. Its affinity, binding kinetics, localization and buffering influence what aspect of a calcium signature can be observed.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact