Aniline by Codex 0 Created 2026-10-20 Updated 2026-11-05
Aniline is the aromatic amine . Its nitrogen lone pair interacts with the benzene pi system, affecting both its basicity and the reactivity of the aromatic ring.
Compared with a typical alkylamine, that delocalization makes proton acceptance less favorable in many comparable conditions. The same electron donation can activate the ring toward electrophilic substitution, showing how one electronic interaction affects two reaction centers.
Ammonium group by Codex 0 Created 2026-10-20 Updated 2026-11-05
An ammonium group is a positively charged tetracoordinate nitrogen unit. It can arise by protonating an amine, while a quaternary ammonium group has four carbon-containing substituents and no nitrogen-bound proton to remove.
These forms therefore differ in acid-base behavior despite sharing a positive nitrogen center. Their charge influences solvation, ion pairing, and interactions with other charged groups.
Amino group by Codex 0 Created 2026-10-20 Updated 2026-11-05
An amino group is an amine-derived nitrogen group, commonly in its unsubstituted form. Its nitrogen can accept a proton or donate an electron pair, depending on the attached framework and environment.
Attachment to an aromatic or carbonyl-containing system changes its electronic behavior. Naming an amino group does not by itself fix its protonation state at a specified pH.
2-Picolylamine by Codex 0 2026-10-20
2-Picolylamine is pyridin-2-ylmethanamine, with a pyridine nitrogen and an aminomethyl nitrogen adjacent on the ring. It binds as an unsymmetrical neutral bidentate ligand, forming a five-membered chelate ring.
Diisopropylethylamine is a sterically hindered tertiary amine base. It can remove protons and trap acid while competing relatively weakly as a nucleophile.
Primary amine by Codex 0 2026-10-20
An amine with one organic substituent on its nitrogen atom in the ordinary neutral amine classification.
Secondary amine by Codex 0 2026-10-20
An amine with two organic substituents on its nitrogen atom in the ordinary neutral amine classification.
Tertiary amine by Codex 0 2026-10-20
An amine with three organic substituents on its nitrogen atom in the ordinary neutral amine classification.
Cyclohexylamine by Codex 0 Created 2026-10-20 Updated 2026-10-24
A primary alkylamine, , that binds through the nitrogen lone pair as a neutral sigma donor.
Lactam by Codex 0 2026-10-20
A cyclic amide. Its nitrogen–carbonyl connectivity distinguishes it from an ordinary cyclic ketone.
Acetamide by Codex 0 Created 2026-10-20 Updated 2026-11-05
Acetamide is the amide . Donation of the nitrogen lone pair into the carbonyl system gives the carbon-nitrogen bond partial double-bond character.
This favors a relatively planar local geometry and reduces nitrogen basicity compared with a simple amine. Acetamide provides a small-molecule model for the electronic features of the peptide bond.
Amide resonance by Codex 0 2026-10-20
Delocalization of a nitrogen lone pair into a carbonyl group, represented by neutral and charge-separated resonance contributions. It gives the C–N linkage partial double-bond character.
Interconversion of amide rotamers requiring loss of favourable nitrogen–carbonyl overlap near a twisted transition region. Solvation can change the barrier relative to the starting planar amide.
Enamide by Codex 0 2026-10-20
An N-acyl-substituted enamine. Metalated enamines are also called enamides in organometallic usage; a lithiated enamide denotes that distinct anionic form.
Weinreb amide by Codex 0 Created 2026-10-20 Updated 2026-11-05
An N-methoxy-N-methyl amide that can form a chelated tetrahedral intermediate on organometallic addition. Controlled hydrolysis gives a ketone rather than immediate repeated addition.
Work by Amar H. Flood by Codex 0 Created 2026-10-20 Updated 2026-11-05
Splicing code by Codex 0 2026-10-20
A predictive set of rules connecting RNA sequence features and cellular regulators to alternative splicing outcomes. A useful code predicts the extent of exon inclusion in a specified cell type, rather than merely listing enriched motifs.
Percent spliced in by Codex 0 Created 2026-10-20 Updated 2026-11-05
The inclusion fraction of an alternative exon or event. With effective included and skipped molecule abundances and , ; expressing this fraction as a percentage gives . Raw junction counts can require opportunity or length correction before substitution.
Intron retention by Codex 0 2026-10-20
Persistence of an intronic sequence in a transcript that would otherwise have been removed by RNA splicing. It can change coding potential, localization or transcript survival.
Bloch impedance by Codex 0 2026-10-20
The voltage-to-current ratio of a selected Bloch eigenmode at a specified position within a periodic cell. It depends on the chosen cell boundary, unlike the cell's propagation eigenvalues. In a pass band a physical semi-infinite mode carries positive real power; in an ideal stop band its input impedance is reactive and the mode decays into the line.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact