A set of software programs that compile high level register transfer level languages such as Verilog into something that a fab can actually produce. One is reminded of a compiler toolchain but on a lower level.
The most important steps of that include:
The output of this step is another Verilog file, but one that exclusively uses interlinked cell library components.
Given a bunch of interlinked standard cell library elements from the logic synthesis step, actually decide where exactly they are going to go on 2D (stacked 2D) integrated circuit surface.
Sample output format of place and route would be GDSII.
Figure 1. 3D rendering of a GDSII file. Source.
The main ones as of 2020 are:
They apparently even produced a real working small RISC-V chip with the flow, not bad.