Cyrus Samii is a political scientist at New York University whose methodological work concerns quantitative field research and causal inference. His academic biography connects the design of randomized controlled trials to empirical social research.[ref]
Figure 1.
Cyrus Samii
. Portrait linked as cds_self from Samii's personal academic biography; served directly by the original website.
With Peter M. Aronow, Samii studied sampling designs in which every unit can be observed but some pairs can never be observed together. The distinction matters: positive individual inclusion probabilities suffice for an unbiased estimator of a finite population total, whereas the usual Horvitz-Thompson variance estimator also needs pairwise inclusion positivity.[ref]
An original two-unit example makes the single-draw variance identifiability obstruction explicit. Fix two unknown population values and choose one index with probabilities . The Horvitz-Thompson estimator is , so
An estimator based only on the selected index and its observed value has expected value of the form . Such an additive expression cannot equal for every pair of real values. Taking the mixed finite difference at gives zero for the additive expression but
for the desired variance. Thus a single draw permits an unbiased estimator of the total but no universally unbiased estimator of its sampling variance. Independent auxiliary randomization cannot repair this: averaging that randomness still gives functions and of the same observed data.
This is a restriction imposed by the observation mechanism, rather than a shortage of algebraic ingenuity. It motivates separating design-based inference about a total from the additional information needed to quantify its uncertainty.

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