Its activity helps copy a CG methylation pattern after DNA replication. Reduced MET1 function can therefore change heritable chromatin states while leaving the corresponding DNA base order unchanged; this separates an epigenetic mark from a sequence mutation. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapters 4–7, chromatin, replication and gene regulation
Articles by others on the same topic
There are currently no matching articles.