Past exam of the short options paper shared by Prelims and Parts A and B of the physics course of the University of Oxford / 2017 / S12 / 2 / 1 / Solution

Let $U(x)$ be the static potential and $\gamma$ the drag coefficient, so terminal Genetic drift under force $-U^{\prime }$ is $v=-U^{\prime }/\gamma$. The probability current is $J=-D{U}^{\prime }p/(k_{B}T)$ only after imposing the desired relation; instead start independently from $J=-D{p}^{\prime }-U^{\prime }p/\gamma$. At thermal equilibrium $p\propto e^{-U/(k_{B}T)}$ and detailed balance requires $J=0$. Substitution yieldsAt 298 K with $a=0.5\mu$m, this gives approximately $4.37\times 10^{-13}$ m${}^2$ s${}^{-1}$. The argument assumes an overdamped particle in an equilibrium thermal bath, rather than arbitrary driven diffusion.