An **Intelligent Enterprise** refers to an organization that leverages advanced technologies, data analytics, and automation to enhance efficiency, improve decision-making, and create value. The concept integrates various digital capabilities and data-driven insights to respond quickly to market changes, customer demands, and operational challenges.
Staffing models refer to structured frameworks or methodologies that organizations use to determine their workforce needs, allocate resources, and manage human capital effectively. These models help in forecasting staffing requirements, optimizing employee roles, and ensuring that the right number of employees with the right skills are available to meet organizational goals. Key elements of staffing models include: 1. **Workforce Planning**: Assessing current staffing levels, predicting future needs based on factors like business growth, market trends, and turnover rates.
Heinrich Hertz's main initial experiment used a spark-gap transmitter. It is not something that transmits recorded sounds like voice: it only transmits noisy beeps. And as such was used for wireless telegraphy.
- a piezo igniter from a barbequeue lighter
- a more powerful home-made transformer
Hertz and Radio waves Explained by PhysicsHigh (2016)
Source. Simple schematics showing the basics of the experiments. No choice of components rationale.Instead of trying to dominate the sequencing market and gain trillions of dollars from it, they local British early stage investors were more than happy to get a 20x return on their small initial investments, and sold out to the Americans who will then make the real profit.
And now Solexa doesn't even have its own Wikipedia page, while Illumina is set out to be the next Microsoft. What a disgrace.
Cambridge visitors can still visit the Panton Arms pub, which was the location of the legendary "hey we should talk" founders meeting, chosen due to its proximity to the chemistry department of the University of Cambridge.
In 2021 the founders were awarded the Breakthrough Prize. The third person awarded was Pascal Mayer. He was apparently at Serono Pharmaceutical Research Institute at the time of development. They do have a wiki page unlike Solexa: en.wikipedia.org/wiki/Serono. They paid a 700 million fine in 2005 in the United States, and sold out in 2006 to Merck for 10 billion USD.
Bibliography:
- medium.com/@nick.mccooke/how-we-pioneered-next-generation-dna-sequencing-at-solexa-61bac41aedd2 How We Pioneered Next Generation DNA Sequencing At Solexal by Nick McCooke 2025. This article series could be very interesting.
Quantum is getting hot in 2019, and even Ciro Santilli got a bit excited: quantum computing could be the next big thing.
No useful algorithm has been economically accelerated by quantum yet as of 2019, only useless ones, but the bets are on, big time.
To get a feeling of this, just have a look at the insane number of startups that are already developing quantum algorithms for hardware that doesn't/barely exists! quantumcomputingreport.com/players/privatestartup (archive). Some feared we might be in a bubble: Are we in a quantum computing bubble?
To get a basic idea of what programming a quantum computer looks like start by reading: Section "Quantum computing is just matrix multiplication".
Some people have their doubts, and that is not unreasonable, it might truly not work out. We could be on the verge of an AI winter of quantum computing. But Ciro Santilli feels that it is genuinely impossible to tell as of 2020 if something will work out or not. We really just have to try it out and see. There must have been skeptics before every single next big thing.
This is a term "invented" by Ciro Santilli to refer to quantum compilers that are able to convert non-specifically-quantum (functional, since there is no state in quantum software) programs into quantum circuit.
The term is made by adding "quantum" to the more "classical" concept of "high-level synthesis", which refers to software that converts an imperative program into register transfer level hardware, typicially for FPGA applications.
It is a bit hard to decide if those people are serious or not. Sometimes it feels scammy, but sometimes it feels fun and right!
Particularly concerning is the fact that they are not a not-for-profit entity, and it is hard to understand how they might make money.
Charles Simon, the founder, is pretty focused in how natural neurons work vs artificial neural network models. He has some good explanations of that, and one major focus of the project is their semi open source spiking neuron simulator BrainSimII. While Ciro Santilli believes that there might be insight in that, he also has doubts if certain modules of the brain wouldn't be more suitable coded directly in regular programming languages with greater ease and performance.
FutureAI appears to be Charles' retirement for fun project, he is likely independently wealthy. Well done.
- www.aitimejournal.com/interview-with-charles-simon-ceo-and-founder-futureai
- 2022 raised 2 million USD:
Creativity and AGI by Charles Simon's at AGI-22 (2022)
Source. Sounds OK!- youtu.be/ivbGbSx0K8k?t=856 general structure of the human brain 86B total, matching number of neurons in the human brain, with:
- 14B: brainstem
- 16B: neocortex
- 56B: cerebelum
- www.youtube.com/watch?t=1433 some sequencing ideas/conjectures
Machine Learning Is Not Like Your Brain by Future AI (2022)
Source. Contains some BrainSimII demos.The CNOT gate is a controlled quantum gate that operates on two qubits, flipping the second (operand) qubit if the first (control) qubit is set.
Equation 1.
CNOT gate matrix
. CNOT gate symbol
. Source. The symbol follow the generic symbol convention for controlled quantum gates shown at Figure "Generic controlled quantum gate symbol", but replacing the generic "U" with the Figure "Quantum NOT gate symbol".On the standard basis:we see that this means that only and should be possible. Therefore, the state must be of the form:where and are two complex numbers such that
If we operate the CNOT gate on that state, we obtain:and so the input is unchanged as desired, because the control qubit is 0.
Therefore, in that case, what happened is that the probabilities of and were swapped from and to and respectively, which is exactly what the quantum NOT gate does.
So from this we understand more concretely what "the gate only operates if the first qubit is set to one" means.
Now go and study the Bell state and understand intuitively how this gate is used to produce it.
Axel Firsoff was a prominent figure in the field of astronomy, particularly known for his work in astrobiology and for advocating scientific literacy. He made contributions to the understanding of astrobiology, which studies the origin, evolution, distribution, and future of life in the universe.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 3. Visual Studio Code extension installation.Figure 4. Visual Studio Code extension tree navigation.Figure 5. Web editor. You can also edit articles on the Web editor without installing anything locally.Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





