KCNQ channels, also known as M-type potassium channels, are a family of voltage-gated potassium channels that are encoded by the KCNQ gene family. These channels play a crucial role in regulating neuronal excitability and are important for setting the resting membrane potential and shaping action potentials in neurons and other excitable cells.
KCNQ5 is a gene that encodes a member of the potassium voltage-gated channel subfamily Q. The channels formed by KCNQ5 are involved in various physiological processes, including regulating the excitability of neurons and other types of cells. This specific potassium channel is known to contribute to the M-current, which is a slow, voltage-gated potassium current that helps stabilize the membrane potential and can influence the firing patterns of action potentials in neurons.
KCNQ4 is a gene that encodes a potassium ion channel, which is part of the KCNQ (Kv7) family of voltage-gated potassium channels. These channels are important for the regulation of electrical activity in various tissues, particularly in the nervous system and the inner ear. KCNQ4 specifically plays a critical role in the auditory system, where it helps to control the membrane potential of hair cells in the cochlea.
KCNN4, also known as the potassium voltage-gated channel subfamily N member 4, is a gene that encodes a protein belonging to a family of ion channels. These types of ion channels are involved in various physiological processes, including the regulation of electrical activity in neurons and muscle cells, as well as modulation of various hormonal and neurotransmitter responses. KCNN4 specifically encodes a calcium-activated potassium channel, which means that its activity is stimulated by the presence of calcium ions.
KCNN2, or "Potassium Calcium-Activated Channel Subfamily N Member 2," is a gene that encodes a protein belonging to the SK (small-conductance Ca^2+-activated K^+) channel family. These channels play a vital role in regulating neuronal excitability and smooth muscle contraction by allowing potassium ions to flow out of cells in response to increases in intracellular calcium levels.
KCNN1, or potassium calcium-activated channel subfamily N member 1, is a gene that encodes a protein involved in the regulation of ion channels in mammalian cells. The KCNN1 protein plays a role in the modulation of potassium ion (K+) currents and is part of a group of channels known as the potassium calcium-activated channels (also known as SK channels or small conductance calcium-activated potassium channels).
KCNMB4, or Potassium Calcium-Activated Channel Subfamily M Beta Member 4, is a gene that encodes a protein subunit which plays a role in forming potassium channels in various tissues, including the nervous system, cardiovascular system, and smooth muscle. These channels are involved in regulating various physiological processes, including vascular tone and neurotransmitter release.
KCNMB3 is a gene that encodes a protein known as the potassium calcium-activated channel subfamily M member 3. This protein is part of a family of ion channels that are important for various physiological functions, particularly in the nervous and cardiovascular systems. KCNMB3 is known to form a subunit of large conductance calcium-activated potassium (BK) channels, which play a crucial role in regulating membrane potential and calcium signaling in cells.
KCNMB2 (Potassium Calcium-Activated Channel Subfamily M Beta 2) is a gene that encodes a protein involved in the functioning of calcium-dependent potassium channels. These channels are crucial for various physiological processes, including the regulation of smooth muscle contraction and neuronal excitability. The KCNMB2 protein acts as a beta subunit of large-conductance calcium-activated potassium (BK) channels.
KCNMB1 (Potassium Calcium-Activated Channel Subfamily M Beta Member 1) is a gene that encodes a protein involved in the regulation of potassium ion channels. Specifically, it is known to be a regulatory beta subunit for a class of calcium-activated potassium (BK) channels, which play a crucial role in various physiological processes such as smooth muscle contraction, neuronal signaling, and cardiac function.
KCNK9, also known as "potassium channel sodium-activated 9," is a gene that encodes a protein belonging to the potassium channel family. This family of proteins is involved in the regulation of potassium ion flow across cell membranes, which is crucial for various physiological processes, including maintaining the resting membrane potential, shaping action potentials, and regulating cellular excitability.
KCNK7, also known as potassium channel subfamily K member 7, is a gene that encodes a protein belonging to the two-pore domain potassium (K2P) channel family. These channels play a crucial role in maintaining the resting membrane potential and regulating excitability in various cell types, particularly neurons and cardiac muscle cells.
KCNK6, also known as TWIK-related K+ channel 6, is a gene that encodes a protein belonging to the two-pore domain potassium channel (K2P) family. These channels are known for their role in maintaining the resting membrane potential and regulating the excitability of neurons and other cells by allowing potassium ions (K+) to flow across the cell membrane. KCNK6 is characterized by its ability to contribute to the background potassium conductance in various tissues.
KCNK5, also known as "Potassium Channel, Two-Pore Domain, Subfamily K, Member 5," is a gene that encodes a protein involved in the formation of a specific type of potassium ion channel. These channels are integral in various physiological processes, including setting the resting membrane potential of cells, regulating excitability, and contributing to the overall homeostasis of potassium ions within cells.
KCNK4, also known as potassium channel subfamily K member 4, is a gene that encodes a protein belonging to the two-pore domain potassium channel family. These channels are involved in the regulation of potassium ion flow across cell membranes, which plays a critical role in various physiological processes, including the maintenance of resting membrane potential, regulation of excitability in neurons and muscle cells, and influencing heart rhythm.
KCNK3 is a gene that encodes a protein known as potassium channel subfamily K member 3 (also referred to as K2P3.1). This protein is part of a group of channels known as two-pore domain potassium channels (K2P channels), which are involved in controlling the flow of potassium ions across the cell membrane.
KCNK2, also known as K2P2.1 or TREK-1, is a gene that encodes for a member of the two-pore domain potassium channel family. This channel plays a significant role in regulating the electrical activity of neurons and other cells by allowing potassium ions to flow across the cell membrane, which is crucial for maintaining the resting membrane potential and contributing to the repolarization phase of action potentials.
KCNK18, also known as potassium channel subfamily K member 18, is a gene that encodes a member of the two-pore domain potassium channel family. These channels are important for regulating various physiological processes by controlling potassium ion flow across cell membranes. KCNK18 is specifically involved in setting the resting membrane potential and regulating excitability in neuronal and muscle tissues. The KCNK18 protein may play a role in the sensory system and is thought to be involved in pain perception.
KCNK17, also known as potassium channel, subfamily K, member 17, is a gene that encodes a member of the two-pore domain potassium channel family. These channels are involved in various physiological processes, including the regulation of neuronal excitability and cardiac rhythm. KCNK17 specifically is thought to play a role in the modulation of the resting membrane potential of cells and may be involved in sensory perception.
KCNK16, also known as "potassium channel, subfamily K, member 16," is a gene that encodes a protein which is part of the two-pore domain potassium channel (K2P) family. These channels are involved in the regulation of potassium ion permeability across cell membranes and play a critical role in maintaining the cell's resting membrane potential, contributing to various physiological processes such as muscle contraction, neurotransmitter release, and the regulation of excitability in neurons.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact