WebGeSTer is a web-based tool designed for the visualization and analysis of genomic sequence data, particularly focused on genomic structural variants like structural rearrangements, copy number variations, and other complex genomic features. It aims to provide researchers with an accessible platform to explore and interpret genomic data efficiently. WebGeSTer typically allows users to: 1. **Visualize Genomic Data:** Users can view genomic information in a user-friendly interface, facilitating the interpretation of complex data sets.
Western blot is a widely used analytical technique in molecular biology and biochemistry to detect and quantify specific proteins in a sample. The process involves several key steps: 1. **Sample Preparation**: Proteins are extracted from cells or tissues and denatured, usually by heating and adding a reducing agent, to ensure that they unfold and are separated by size.
A zinc finger inhibitor refers to a type of compound or molecule that can inhibit the function or activity of zinc finger proteins. Zinc finger proteins are a large family of proteins that are characterized by the presence of zinc finger motifs, which are structural motifs stabilized by the binding of zinc ions. These motifs enable the proteins to bind to DNA, RNA, or other proteins, playing crucial roles in a variety of biological processes, including gene regulation, signal transduction, and cellular differentiation.
Zinc finger protein 613 (ZNF613) is a member of the zinc finger protein family, which is characterized by the presence of one or more zinc finger domains. These domains are structural motifs that can bind zinc ions and are involved in the binding of DNA, RNA, or other proteins, playing crucial roles in transcription regulation, DNA repair, and other cellular processes. ZNF613 is encoded by the ZNF613 gene in humans, located on chromosome 12.
A molecular assembler is a hypothetical device or system that is capable of constructing complex molecular structures by manipulating individual atoms and molecules with precision. The concept primarily relates to nanotechnology and molecular manufacturing, where the idea is to build materials and products at the atomic or molecular level.
"Bailar twist" refers to a dance style or move that combines elements of traditional dancing with a twist or flair. The term "bailar" means "to dance" in Spanish, so "bailar twist" suggests a playful or innovative approach to dance. It might involve twisting movements, dynamic rhythms, and a fusion of different dance techniques.
A bicyclic molecule is a type of chemical compound that contains two interconnected rings in its structure. These rings can share one or more atoms, leading to a variety of possible configurations. Bicyclic molecules can be characterized by their topology, symmetry, and the types of atoms they include (such as carbon, nitrogen, or oxygen).
T-shaped molecular geometry is a type of molecular arrangement that occurs in certain molecules with a central atom bonded to three other atoms and with one lone pair of electrons. This geometry is typically associated with the VSEPR (Valence Shell Electron Pair Repulsion) theory, which predicts the shape of molecules based on the repulsions between electron pairs around a central atom. In T-shaped molecules, the central atom has five regions of electron density, which includes three bonding pairs and two lone pairs.
A polyhedral symbol is a mathematical notation used to describe and classify various types of polyhedra, particularly in the context of combinatorial and geometric studies. Polyhedra are three-dimensional shapes with flat polygonal faces, and the polyhedral symbol encodes information such as the types and configurations of these faces.
In chemistry, a "ring" refers to a cyclic structure in which atoms are connected in a closed loop. These rings can consist of various types of atoms, including carbon, nitrogen, oxygen, and others. Ring structures are crucial in organic chemistry and biochemistry, as many important molecules feature these configurations. Common types of rings include: 1. **Cyclic hydrocarbons**: Molecules that consist entirely of carbon and hydrogen atoms arranged in a ring.
Square planar molecular geometry is a type of molecular arrangement where a central atom is surrounded by four other atoms or groups, all lying in the same plane and forming a square shape. This geometry typically occurs when the central atom is in a state of d2sp3 hybridization and has an octahedral electron pair geometry. Key characteristics of square planar geometry include: 1. **Bond Angles**: The bond angles between the surrounding atoms are 90 degrees.
Square pyramidal molecular geometry is a specific arrangement of atoms in a molecule or ion where a central atom is surrounded by five other atoms. In this geometry, four of the surrounding atoms are located at the corners of a square base, and one atom is positioned above the center of the square, forming a pyramid-like structure.
Synthetic molecular motors are engineered molecules that can transduce energy into directed motion at the nanoscale. These motors are designed to mimic the function of natural motors found in biological systems, such as proteins and enzymes that perform tasks vital to cellular functions, including muscle contraction and the movement of organelles. Synthetic molecular motors differ from their biological counterparts in that they are artificially created and can be tailored for specific applications.
The International Academy of Quantum Molecular Science (IAQMS) is a prestigious organization dedicated to advancing research and education in the fields of quantum chemistry and molecular science. Founded in 1967, the academy comprises leading scientists and researchers from around the world who are recognized for their contributions to the study of molecular systems using quantum mechanical approaches. The IAQMS aims to foster international collaboration in research, promote the exchange of scientific ideas, and enhance the understanding and application of quantum molecular science.
Vibronic coupling refers to the interaction between electronic states and vibrational states in a molecular system. This phenomenon is crucial for understanding various processes in molecular physics and chemistry, including spectroscopy, photochemistry, and energy transfer. In more detail, vibronic coupling arises when there is a significant overlap between electronic states that leads to the mixing of their corresponding vibrational states. This interaction can occur due to changes in the molecular geometry that happen when electrons transition between different energy levels.
The second moment of area, also known as the area moment of inertia or the second moment of inertia, is a measure of an object's resistance to bending or flexural stress. It represents how the area is distributed about a given axis. The second moment of area is important in engineering fields such as structural and mechanical engineering for analyzing materials' flexural behavior.
A molecular orbital (MO) is a region in a molecule where there is a high probability of finding electrons. In quantum chemistry, molecular orbitals are formed by the linear combination of atomic orbitals (LCAO) when atoms bond together to form a molecule. These orbitals can be occupied by electrons and can describe the distribution of electrons in the molecule.
The North Atlantic Track Agreement refers to a set of procedures established for aircraft operations over the North Atlantic Ocean. Specifically, it addresses the routing of transatlantic flights to enhance safety and efficiency. The agreement involves the coordination of air traffic control authorities from different countries, allowing for optimized flight paths, reduced travel time, and better management of airspace during busy periods. The North Atlantic Tracks (NAT) are predefined routes that are periodically adjusted based on aircraft traffic and prevailing weather conditions, including jet streams.
A quadrupole refers to a specific arrangement of four electric charges, magnetic poles, or masses. It is most commonly encountered in the contexts of electromagnetism, nuclear physics, and mechanical systems.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 3. Visual Studio Code extension installation.Figure 4. Visual Studio Code extension tree navigation.Figure 5. Web editor. You can also edit articles on the Web editor without installing anything locally.Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





