Backlinks to Ciro Santilli's website by
Ciro Santilli 37 Updated 2025-05-21 +Created 1970-01-01
Transportation in the United Kingdom by
Ciro Santilli 37 Updated 2025-05-21 +Created 1970-01-01
Why it takes several days to enter inflammatory phase in COVID-19? by
Ciro Santilli 37 Updated 2025-05-21 +Created 1970-01-01
Why is it there such a clear separation of phases?
Why do people with mild symptoms go on to die? It is a great mystery.
Ciro Santilli's theory is that COVID is extremely effective at avoiding immune response. Then, in people where this is effective, things reach a point where there is so much virus, that the body notices and moves on to take a more drastic approach. This is compatible with the virus killing older people more, as they have weaker immunes systems. This is however incompatible with the fact that people don't seem to be contagious after the viral phase is over...
Why is COVID-19 so serious in some people but not in others? by
Ciro Santilli 37 Updated 2025-05-21 +Created 1970-01-01
There are a few possibilities:
- genetics
- bibliography:
- www.science.org/doi/10.1126/scitranslmed.abj7521 Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort by Carapito et al. (2021)
- bibliography:
- state of the immune system based on disease history
- age
Some interesting usages:
- www.cell.com/cell/fulltext/S0092-8674(15)00568-1 2015. Using Genome-scale Models to Predict Biological Capabilities. Edward J. O'Brien, Jonathan M. Monk, Bernhard O. Palsson.
- www.quora.com/What-are-some-good-books-on-Escherichia-Coli-E-Coli
Size: 1-2 micrometers long and about 0.25 micrometer in diameter, so:
2 * 0.5 * 0.5 * 10e-18
and thus 0.5 micrometer square.Reference strain: E. Coli K-12 MG1655.
Genome:
- 4k genes
- 5 Mbps
- www.ncbi.nlm.nih.gov/genome/167
wget ftp://ftp.ncbi.nlm.nih.gov/genomes/all/GCF/000/005/845/GCF_000005845.2_ASM584v2/GCF_000005845.2_ASM584v2_genomic.fna.gz
wget -O NC_000913.3.fasta 'https://www.ncbi.nlm.nih.gov/search/api/sequence/NC_000913.3/?report=fasta'
Synthesis project: www.sciencemag.org/news/2016/08/biologists-are-close-reinventing-genetic-code-life
Omics modeling: www.ncbi.nlm.nih.gov/pmc/articles/PMC5611438/ Tools for Genomic and Transcriptomic Analysis of Microbes at Single-Cell Level Zixi Chen, Lei Chen, Weiwen Zhang.
Pinned article: ourbigbook/introduction-to-the-ourbigbook-project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact