Organ-on-a-chip is a technology that involves creating micro-engineered devices that mimic the functions and structures of human organs. These miniaturized systems integrate living cells and biomaterials in a way that simulates the physiological environment of an organ. The goal is to replicate specific organ systems to study biological processes, disease mechanisms, drug responses, and to optimize therapeutic strategies.
Shu Jie Lam does not appear to refer to any widely recognized person, concept, or term as of my last update in October 2023. It is possible that it refers to a specific individual, perhaps in a niche or emerging context not captured in my training data.
A homologous series is a group of organic compounds that share a common structural formula and have similar chemical properties, yet differ from each other by a specific number of methylene groups (-CH₂-) or a similar repeating unit. The members of a homologous series exhibit a gradual change in physical properties, such as melting and boiling points, as the molecular weight increases.
Protein crystallization is a laboratory technique used to form well-ordered crystals of proteins. This process is essential for studying the three-dimensional structures of proteins using X-ray crystallography, a powerful method for determining atomic arrangements in biological macromolecules. The main steps involved in protein crystallization typically include: 1. **Protein Purification**: Before crystallization, the protein of interest must be isolated and purified. This can involve techniques such as affinity chromatography, ion-exchange chromatography, and gel filtration.
A Southwell plot is a graphical representation used primarily in the field of geotechnical engineering and soil mechanics to interpret the behavior of soil under loading conditions. It is particularly useful for analyzing the failure of soil structures, such as retaining walls or shallow foundations, and is often employed in the context of slope stability analysis. In a Southwell plot, the vertical axis typically represents the degree of movement or displacement of the soil structure, while the horizontal axis represents the load or pressure applied to the soil.
The Wigner-Seitz cell is a concept in solid-state physics and crystallography that is used to describe the local environment of atoms in a crystalline lattice. It is essentially a way to define a unit cell that encompasses the region around a lattice point, giving a clear representation of how space is partitioned among the particles in a crystal.
The William Prager Medal is an award given by the Society for Experimental Mechanics (SEM) to recognize outstanding contributions to the field of experimental mechanics. It is named after William Prager, a prominent figure in mechanics and materials science. The medal is typically awarded to individuals who have made significant advancements or innovations in experimental methods, techniques, and research that have advanced the field.
A dual-rotor permanent magnet induction motor (DPMIM) is an advanced type of electric motor that incorporates features from both permanent magnet motors and induction motors. The design typically includes two rotors, which can enhance the motor's efficiency, torque density, and performance in various applications. ### Key Features: 1. **Dual-Rotor Configuration**: The presence of two rotors allows for improved torque characteristics and can help in balancing the motor's performance.
In engineering, a "groove" refers to a narrow channel or indentation formed in a material, typically to accommodate a component, provide a pathway for a fluid, or facilitate certain mechanical functions. Grooves can be found in various applications including: 1. **Mechanical Engineering**: Grooves are used in creating surfaces for bonding or sealing, such as in gaskets or O-rings, and in the design of bearings to reduce friction.
A jet nut, also known as a jet lock nut or jet hex nut, is a type of fastener that incorporates a feature designed to prevent loosening due to vibration or thermal expansion. Jet nuts are typically used in aerospace and other high-performance applications where reliability is critical. These nuts often have a nylon insert or a similar locking mechanism that grips the threads of the bolt, helping to keep the nut securely fastened in place.
A split pin, also known as a cotter pin or clevis pin, is a type of fastening device typically made from metal. It consists of a pin with a split or two prongs at one end. The split allows the pin to be inserted into a hole and then bent or spread apart, securing it in place. Split pins are commonly used in various applications, including: 1. **Mechanical Assemblies**: To secure components in place, such as in machinery or vehicles.
ASME QME-1, or the "ASME Standard for Qualification of Nondestructive Examination (NDE) Personnel for Qualification of Nondestructive Examiners in Nuclear Power Plants," is a standard developed by the American Society of Mechanical Engineers (ASME). It provides guidelines and requirements for the qualification of personnel conducting nondestructive examination (NDE) in nuclear environments.
Electrochemical potentials refer to the ability of an electrochemical system, which involves chemical reactions and electric charges, to perform work or drive reactions due to differences in energy. Understanding electrochemical potentials is fundamental to fields like electrochemistry, battery technology, corrosion science, and fuel cells. ### Key Concepts: 1. **Gibbs Free Energy**: The electrochemical potential is often related to changes in Gibbs free energy (ΔG) for a reaction.
Continuous adsorption-regeneration is a process used primarily in industrial applications for the removal or recovery of specific substances (such as pollutants, contaminants, or valuable materials) from a liquid or gas stream through an adsorption mechanism, followed by a regeneration phase that restores the adsorbent's capacity for further use. This two-step process is designed to operate continuously, maximizing efficiency and minimizing downtime.
Electrochemical regeneration refers to a process where an electrochemical cell is used to restore or regenerate a substance, often a catalyst, reactant, or solution, thereby allowing it to be reused in a chemical process. This technique is commonly applied in various fields, including waste treatment, energy storage, and environmental remediation.
As of my last knowledge update in October 2021, there is no widely-known financial institution or entity called "Crary Bank." It's possible that it could refer to a small or local bank, a banking service, or a new establishment that has emerged after my last update.
Gumdrop Seamount is an underwater volcanic feature located in the northern Pacific Ocean, specifically within the Aleutian Islands arc off the southern coast of Alaska. It is categorized as a seamount, which is a submerged mountain formed by volcanic activity, typically rising at least 1,000 meters (3,280 feet) from the seabed but not reaching the ocean surface.
The Kenn Plateau is a geological feature located in the region of southeastern Queensland, Australia. It is characterized by its elevated landform, which has been shaped by volcanic activity and erosion over millions of years. The plateau is known for its unique ecosystems, which include a variety of flora and fauna, some of which are endemic to the region. Additionally, the Kenn Plateau may be associated with cultural and historical significance, as many regions in Australia have Indigenous connections.
Bestrophin 1 (BEST1) is a protein that is encoded by the BEST1 gene in humans. It is primarily expressed in retinal cells, particularly in the retinal pigment epithelium (RPE), and plays an important role in the function of the retina. Bestrophin 1 is believed to be involved in the regulation of ion channels, particularly chloride channels, and is thought to have a role in maintaining the ionic balance and fluid homeostasis in the eye.
GABRA3 is a gene that encodes the gamma-aminobutyric acid (GABA) type A receptor subunit alpha3. GABA receptors are the major inhibitory neurotransmitter receptors in the central nervous system (CNS) and play a crucial role in regulating neuronal excitability and synaptic transmission. The GABRA3 protein is part of the pentameric structure that forms the GABA A receptor, which consists of five subunits.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact