Man-made virus!
TODO: if we had cheap de novo DNA synthesis, how hard would it be to bootstrap a virus culture from that? github.com/cirosantilli/cirosantilli.github.io/issues/60
Is it easy to transfect a cell with the synthesized DNA, and get it to generate full infectious viral particles?
If so, then de novo DNA synthesis would be very similar to 3D printed guns: en.wikipedia.org/wiki/3D_printed_firearms.
It might already be possible to order dissimulated sequences online:
The algorithmically minded will have noticed that paging requires associative array (like Java
Map of Python dict()) abstract data structure where:The single level paging scheme uses a simple array implementation of the associative array:and in C pseudo-code it looks like this:
- the keys are the array index
- this implementation is very fast in time
- but it is too inefficient in memory
linear_address[0] = physical_address_0
linear_address[1] = physical_address_1
linear_address[2] = physical_address_2
...
linear_address[2^20-1] = physical_address_NBut there another simple associative array implementation that overcomes the memory problem: an (unbalanced) k-ary tree.
Using a K-ary tree instead of an array implementation has the following trade-offs:
In C-pseudo code, a 2-level K-ary tree with and we have the following arrays:
K = 2^10 looks like this:level0[0] = &level1_0[0]
level1_0[0] = physical_address_0_0
level1_0[1] = physical_address_0_1
...
level1_0[2^10-1] = physical_address_0_N
level0[1] = &level1_1[0]
level1_1[0] = physical_address_1_0
level1_1[1] = physical_address_1_1
...
level1_1[2^10-1] = physical_address_1_N
...
level0[N] = &level1_N[0]
level1_N[0] = physical_address_N_0
level1_N[1] = physical_address_N_1
...
level1_N[2^10-1] = physical_address_N_Nand it still contains
2^10 * 2^10 = 2^20 possible keys.K-ary trees can save up a lot of space, because if we only have one key, then we only need the following arrays:
Hardcoded and unique network addresses for every single device on Earth.
Started with 48 bits (6 bytes), usually given as 01:23:45:67:89:AB but people now encouraged to use 64-bit ones.
How they are assigned: www.quora.com/How-are-MAC-addresses-assigned Basically IEEE gives out the 3 first bytes to device manufacturers that register, this is called the organizationally unique identifier, and then each manufacturer keeps their own devices unique.
Like PCR, but does not require thermal cycling. Thus the "isothermal" in the name: iso means same, so "same temperature".
Not needing the thermo cycling means that the equipment needed is much smaller and cheaper it seems.
Big goals:
- the pursuit of AGI
- physics simulations, including scientific visualization software
- formalization of mathematics
The Social Network: dinner with Sean Parker
. Source. Published by Werner Heisenberg in 1925-07-25 as quantum mechanical re-interpretation of kinematic and mechanical relations by Heisenberg (1925), it offered the first general formulation of quantum mechanics.
It is apparently more closely related to the ladder operator method, which is a more algebraic than the more analytical Schrödinger equation.
It appears that this formulation makes the importance of the Poisson bracket clear, and explains why physicists are so obsessed with talking about position and momentum space. This point of view also apparently makes it clearer that quantum mechanics can be seen as a generalization of classical mechanics through the Hamiltonian.
QED and the men who made it: Dyson, Feynman, Schwinger, and Tomonaga by Silvan Schweber (1994) mentions however that relativistic quantum mechanics broke that analogy, because some 2x2 matrix had a different form, TODO find that again.
Inward Bound by Abraham Pais (1988) chapter 12 "Quantum mechanics, an essay" part (c) "A chronology" has some ultra brief, but worthwhile mentions of matrix mechanics and the commutator.
a165c82cf21a6bae54dde98b7e00ab43b695debb59dfe7d279ac0c59d6043e24 by 
Ciro Santilli 40 Updated 2025-07-16
Ciro Santilli 40 Updated 2025-07-16Sister transaction of 4373b97e4525be4c2f4b491be9f14ac2b106ba521587dad8f134040d16ff73af with another variant of the XSS but without IF and
OP_FROMALTSTACK, thus making it spendable:OP_ADD OP_ADD 13 OP_EQUAL <large xss constant> OP_DROP Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 3. Visual Studio Code extension installation.
Figure 4. Visual Studio Code extension tree navigation.
Figure 5. Web editor. You can also edit articles on the Web editor without installing anything locally.Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact