Nature Scitable by Ciro Santilli 40 Updated 2025-07-16
As of 2022 visible at: www.nature.com/scitable
Apparently they had a separate URL as just scitable.com, so they were somewhat serious about it before shutting it down.
As of 2022 marked:
This page has been archived and is no longer updated
RIP.
www.nature.com/scitable/blog/student-voices/ has last entry 2015, so presumably that's the shutdown year.
Self description:
Using our platform, you can customize your own eBooks for your students. Create an online classroom. Contribute and share content and connect with networks of colleagues.
so quite related to OurBigBook.com.
Wikipedia dumps by Ciro Santilli 40 Updated 2025-07-16
Per-table dumps created with mysqldump and listed at: dumps.wikimedia.org/. Most notably, for the English Wikipedia: dumps.wikimedia.org/enwiki/latest/
The tables are "documented" under: www.mediawiki.org/wiki/Manual:Database_layout, e.g. the central "page" table: www.mediawiki.org/wiki/Manual:Page_table. But in many cases it is impossible to deduce what fields are from those docs.
MOOCs are a bad idea. We don't want to simply map the pre-computer classroom to the Internet. The Internet allows, and requires, fundamentally new ways to do things. More like Stack Overflow/Wikipedia. More like OurBigBook.com.
After Ciro Santilli got a lot of attention on Hacker News news.ycombinator.com/item?id=19428700 his Stack Overflow account was suspended for 3 days web.archive.org/web/20190320163458/https://stackoverflow.com/users/895245/ciro-santilli-新疆改造中心-六四事件-法轮功 and he received a magic notification that led to a private message:
Hello,
I'm writing in reference to your Stack Overflow account:
I don't understand why you are actively promoting and assisting people to commit fraud on the site.
I've removed this from your profile github.com/cirosantilli/stack-overflow-vote-fraud-script and do not expect you to post it around the site.
I'm suspending you to gain your attention on this matter.
We have temporarily suspended your account; you may return after 3 days.
Regards,
To: Aaron Hall ♦;Andy ♦;Baum mit Augen ♦;Bhargav Rao ♦;Bohemian ♦;BoltClock ♦;Brad Larson ♦;ChrisF ♦;Cody Gray ♦;deceze ♦;Ed Cottrell ♦;Flexo ♦;George Stocker ♦;Jean-François Fabre ♦;Jon Clements ♦;josliber ♦;Madara Uchiha ♦;Martijn Pieters ♦;meagar ♦;Michael Myers ♦;Rob ♦;Robert Harvey ♦;Ry- ♦;Samuel Liew ♦;Undo ♦;Yvette Colomb ♦
Ciro's reply was:
Hi mods,
Reply and unsuspend quickly followed, with link still removed:
I suspended you to get your attention. Your attitude about going to Twitter about it does not bode well with me.
Feel free to have whatever you want in your GitHub repo. Just don't advertise tools to make it easier for people to circumvent the rules. As easy or as hard as it may be to circumvent them, you're handing it to people who may not be capable of doing so. It doesn't help.
Don't make threats to upload on an anonymous account. Accounts created to circumvent previous warnings are not welcomed on the site.
We don't need a meta thread to discuss whether it's ok to post voting fraud links in your profile and we definitely don't need to give it anymore publicity.
I'll unsuspend you, now we've had this discussion.
Regards,
A meta thread was later created by Yvette, kudos, to which Ciro answered with the correct unpopular answer that will be downvoted to oblivion: meta.stackoverflow.com/questions/381577/is-it-ok-to-have-links-on-how-to-create-sock-puppets-and-gain-rep-fraudulently-i/381635#381635
Yvette had also previously deleted one or two of Ciro's answers for being duplicates, which is a policy Ciro is against: if the questions are not dupes, a single answer might still directly reply to both of them.
Yvette later announced that she was leaving the website: meta.stackoverflow.com/questions/399495/leaving-the-site-and-the-network-mid-election-is-not-the-best-but-theres-no. This is evil, but Ciro was happy. He does not mean harm to Yvette, but in their limited interaction, Ciro disagreed with her choices.
Video 1.
The Great Places Erased by Suburbia by Not Just Bikes (2022)
Source. Stack Overflow, and other online forums, can serve as a sort of a third place for its more active users.
There's no point.
The question remains there, but people lose the ability to help the asker.
Reputation is meaningless regardless, since JavaScript gurus will always have 1000x more readers than low level junkies.
The deeper problem: the existence of multiple separate websites instead of just using the tags on a single website.
Number of pages: 616!
Don't redistribute clause, and final version by Cambridge University Press, alas, so corrections will never be merged back: web.physics.ucsb.edu/~mark/qft.html. But at least he's collecing erratas for the published (and therefore draft) versions there.
The book is top-level organized in spin 0, spin half, and spin 1. Quite ominous, really.
The preface states that one of its pedagogical philosophies is to "Illustration of the basic concepts with the simplest examples.", so maybe there is hope after all.
Specific type of Josephson junction. Probably can be made tiny and in huge numbers through photolithography.
Figure 1. Source. The superconducting material is light blue, the insulating tunnel barrier is black, and the substrate is green.
Video 1.
Quantum Transport, Lecture 14: Josephson effects by Sergey Frolov (2013)
Source. youtu.be/-HUVGWTfaSI?t=878 mentions maskless electron beam lithography being used to produce STJs.
As mentioned on the introduction, the main objective of the course is to try predict qualitative properties of materials, notably the existence of certain phase transitions, starting from first principle toy models.
Running:
readelf -h hello_world.o
outputs:
Magic:   7f 45 4c 46 02 01 01 00 00 00 00 00 00 00 00 00
Class:                             ELF64
Data:                              2's complement, little endian
Version:                           1 (current)
OS/ABI:                            UNIX - System V
ABI Version:                       0
Type:                              REL (Relocatable file)
Machine:                           Advanced Micro Devices X86-64
Version:                           0x1
Entry point address:               0x0
Start of program headers:          0 (bytes into file)
Start of section headers:          64 (bytes into file)
Flags:                             0x0
Size of this header:               64 (bytes)
Size of program headers:           0 (bytes)
Number of program headers:         0
Size of section headers:           64 (bytes)
Number of section headers:         7
Section header string table index: 3
Running:
readelf -h hello_world.out
outputs:
Magic:   7f 45 4c 46 02 01 01 00 00 00 00 00 00 00 00 00
Class:                             ELF64
Data:                              2's complement, little endian
Version:                           1 (current)
OS/ABI:                            UNIX - System V
ABI Version:                       0
Type:                              EXEC (Executable file)
Machine:                           Advanced Micro Devices X86-64
Version:                           0x1
Entry point address:               0x4000b0
Start of program headers:          64 (bytes into file)
Start of section headers:          272 (bytes into file)
Flags:                             0x0
Size of this header:               64 (bytes)
Size of program headers:           56 (bytes)
Number of program headers:         2
Size of section headers:           64 (bytes)
Number of section headers:         6
Section header string table index: 3
Bytes in the object file:
00000000  7f 45 4c 46 02 01 01 00  00 00 00 00 00 00 00 00  |.ELF............|
00000010  01 00 3e 00 01 00 00 00  00 00 00 00 00 00 00 00  |..>.............|
00000020  00 00 00 00 00 00 00 00  40 00 00 00 00 00 00 00  |........@.......|
00000030  00 00 00 00 40 00 00 00  00 00 40 00 07 00 03 00  |....@.....@.....|
Executable:
00000000  7f 45 4c 46 02 01 01 00  00 00 00 00 00 00 00 00  |.ELF............|
00000010  02 00 3e 00 01 00 00 00  b0 00 40 00 00 00 00 00  |..>.......@.....|
00000020  40 00 00 00 00 00 00 00  10 01 00 00 00 00 00 00  |@...............|
00000030  00 00 00 00 40 00 38 00  02 00 40 00 06 00 03 00  |....@.8...@.....|
Structure represented:
# define EI_NIDENT 16

typedef struct {
    unsigned char   e_ident[EI_NIDENT];
    Elf64_Half      e_type;
    Elf64_Half      e_machine;
    Elf64_Word      e_version;
    Elf64_Addr      e_entry;
    Elf64_Off       e_phoff;
    Elf64_Off       e_shoff;
    Elf64_Word      e_flags;
    Elf64_Half      e_ehsize;
    Elf64_Half      e_phentsize;
    Elf64_Half      e_phnum;
    Elf64_Half      e_shentsize;
    Elf64_Half      e_shnum;
    Elf64_Half      e_shstrndx;
} Elf64_Ehdr;
Manual breakdown:
De novo DNA synthesis by Ciro Santilli 40 Updated 2025-07-16
As of 2018, Ciro Santilli believes that this could be the next big thing in biology technology.
"De novo" means "starting from scratch", that is: you type the desired sequence into a computer, and the synthesize it.
The "de novo" part is important, because it distinguishes this from the already well solved problem of duplicating DNA from an existing DNA template, which is what all our cells do daily, and which can already be done very efficiently in vitro with polymerase chain reaction.
Notably, the dream of most of those companies is to have a machine that sits on a lab bench, which synthesises whatever you want.
TODO current de novo synthesis costs/time to delivery after ordering a custom sequence.
The initial main applications are likely going to be:
but the real pipe dream is building and bootstraping entire artificial chromosomes
News coverage:
Video 1.
Nuclera eDNA enzymatic de novo DNA synthesis explanatory animation (2021)
Source. The video shows nicely how Nuclera's enzymatic DNA synthesis works:

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact