Perturb-seq is a high-throughput technique that combines genetic perturbations (such as CRISPR-based gene editing) with single-cell RNA sequencing to study gene function and cellular responses at a single-cell level. This method allows researchers to systematically investigate how perturbations in specific genes or regulatory elements affect gene expression, cellular behavior, and phenotypic traits.
Sequence analysis is a bioinformatics method used to analyze biological sequences, such as DNA, RNA, or protein sequences. This process involves the comparison and interpretation of sequence data to understand biological functions, evolutionary relationships, genetic variations, and other aspects of molecular biology.
Systems immunology is an interdisciplinary field that integrates principles from immunology, systems biology, and computational modeling to understand the complex interactions within the immune system. It aims to analyze and characterize the immune response as a network of interactions among various components, such as cells, molecules, and pathways, rather than focusing on individual elements in isolation.
Translational research informatics is a field of study that focuses on the integration of data and information science with biomedical research to facilitate the translation of scientific discoveries into practical applications in healthcare. This discipline aims to bridge the gap between laboratory research (bench) and patient care (bedside) by utilizing informatics tools and methodologies to enhance the efficiency of the research process.
Viroinformatics is an interdisciplinary field that combines virology, bioinformatics, and computational biology to analyze and interpret data related to viruses. It involves the use of computational tools and techniques to study viral genomes, viral evolution, and the interactions between viruses and their hosts. Key areas of focus in viroinformatics include: 1. **Genome Sequencing and Annotation**: Analyzing viral genomes to identify genetic features, such as coding regions, regulatory elements, and variants.
BioUML is a software platform designed for computational biology and bioinformatics. It provides tools for modeling biological processes, analyzing biological data, and developing biological simulations. The platform typically includes features for handling various types of biological data, such as genomics, proteomics, and metabolic pathways. BioUML offers a graphical user interface that facilitates modeling and visualization of biological systems, allowing users to create and manipulate complex biological networks and models.
Breath gas analysis is a diagnostic technique that involves measuring and analyzing the composition of gases present in exhaled breath. This method is non-invasive and has gained interest in various fields, including medical diagnostics, environmental monitoring, and occupational health. ### Applications of Breath Gas Analysis: 1. **Medical Diagnostics**: - **Respiratory Diseases**: It can be used to detect diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung infections.
A "Boss Key" is a feature found in some software and applications, particularly games, that allows users to quickly hide or minimize their current window or application in order to disguise what they are doing.
Projectiles are objects that are propelled through the air or through a medium, typically under the influence of gravity. The term is commonly used in physics and engineering to refer to any object that is launched, thrown, or otherwise set into motion. Projectiles can include a wide range of items, from bullets and shells to sports balls and rockets. The motion of a projectile is typically analyzed using the principles of mechanics, particularly kinematics and dynamics.
Ballistic gelatin is a synthetic gelatinous material used primarily in the testing and evaluation of bullets and projectiles. It mimics the density and consistency of human tissue, allowing researchers, forensic scientists, and ammunition manufacturers to study how different projectiles behave upon impact with soft tissues. This is crucial for understanding penetration, expansion, and wound channel creation in ballistic impact scenarios. Ballistic gelatin is typically made from a mixture of gelatin powder and water, set into molds to create blocks or other shapes.
A bulletproof vest, also known as a ballistic vest, is a type of body armor designed to absorb and mitigate the impact of projectiles, such as bullets, and shrapnel from explosives. It is commonly used by law enforcement officers, military personnel, and security professionals to provide protection in combat or dangerous situations. Bulletproof vests are typically made from layers of high-strength fibers, such as Kevlar or Twaron, which are woven together to create a flexible, lightweight material.
Contraves Cora is a programmable medical device designed for the continuous glucose monitoring (CGM) of diabetes patients. It helps users better manage their blood glucose levels by providing real-time data, alerts, and insights into their glucose levels, allowing for more informed decision-making regarding insulin and diet. The device is often part of a broader diabetes management system that includes insulin delivery devices, such as insulin pumps.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact