Protein chemical shift re-referencing is a technique used in NMR (Nuclear Magnetic Resonance) spectroscopy to adjust the chemical shifts of observed resonances to improve accuracy and comparability. In NMR, the chemical shift is a measure of the resonance frequency of a nucleus relative to a reference standard.
Triple-resonance nuclear magnetic resonance (NMR) spectroscopy is a sophisticated technique used primarily in the study of proteins and other complex molecules. This method exploits the interactions between three different nuclear spins (typically involving different isotopes of atoms such as hydrogen, carbon, and nitrogen) to provide detailed information about molecular structure, dynamics, and interactions.
Two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy is a sophisticated technique used to analyze the structural and dynamic properties of molecules, particularly in organic chemistry and biochemistry. This method extends traditional one-dimensional NMR spectroscopy by providing additional information about the interactions between nuclear spins in a molecule. ### Key Features of 2D NMR Spectroscopy: 1. **Dimension Expansion**: In 2D NMR, the information is spread across two frequency dimensions rather than one.
Radiopharmaceuticals are radioactive compounds used in medical imaging and therapy. They combine a radioactive isotope with a pharmaceutical agent, allowing them to be used for diagnosis and treatment of various medical conditions, particularly in the fields of nuclear medicine and oncology. ### Key Aspects of Radiopharmaceuticals: 1. **Diagnosis**: Radiopharmaceuticals are often utilized in imaging techniques such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT).
Nuclear material refers to substances that are capable of undergoing nuclear reactions, particularly fission or fusion, and are used in nuclear reactors, nuclear weapons, and other applications related to atomic energy. The primary types of nuclear materials include: 1. **Fissile Materials**: These are materials that can sustain a nuclear fission chain reaction.
Plutonium hexafluoride (PuF₆) is a chemical compound composed of plutonium and fluorine. It is a highly reactive, toxic, and radioactive substance that appears as a gas at elevated temperatures or as a solid at lower temperatures. Plutonium hexafluoride is particularly significant in the nuclear industry, mainly in the context of nuclear reprocessing and the enrichment of plutonium for use in nuclear reactors and weapons.
Reprocessed uranium refers to uranium that has been recovered from spent nuclear fuel through a chemical process known as reprocessing. When nuclear fuel—usually in the form of uranium dioxide—is used in a nuclear reactor, it undergoes fission, resulting in the production of various products, including plutonium, fission products, and actinides. After the fuel is utilized, it is typically considered waste, but a significant amount of the uranium remains unutilized.
Uranyl nitrate is a chemical compound with the formula UO₂(NO₃)₂. It consists of uranium in the +6 oxidation state and is commonly encountered as a yellow, crystalline solid. Uranyl nitrate is a water-soluble compound and is often used in various applications in nuclear chemistry, radiochemistry, and the production of uranium-based materials.
The Linear No-Threshold (LNT) model is a widely used hypothesis in radiation protection and risk assessment that suggests there is no safe level of exposure to ionizing radiation. According to this model, the risk of cancer and other health effects increases linearly with increasing doses of radiation, even at very low levels.
Uranyl peroxide refers to a chemical compound consisting of uranyl ions (UO₂²⁺) combined with peroxide ions (O₂²⁻). The general formula for uranyl peroxide can be expressed as UO₂(O₂)₂·nH₂O, where "n" indicates the number of water molecules in the crystalline structure.
Weapons-grade nuclear material refers to fissile material that is suitable for use in nuclear weapons. The most commonly discussed materials in this context are uranium and plutonium. 1. **Uranium**: For uranium to be considered weapons-grade, it typically needs to contain a high percentage of the fissile isotope uranium-235 (U-235). Generally, uranium enriched to about 90% or more U-235 is classified as weapons-grade. Natural uranium contains about 0.
Nuclear medicine organizations are professional associations, societies, and bodies that focus on the field of nuclear medicine, which is a medical specialty that uses radioactive materials for diagnosis, treatment, and research of diseases. These organizations typically aim to promote the advancement of nuclear medicine, improve patient care, support education and training, and facilitate collaboration among professionals in the field.
Angelika Bischof-Delaloye is a recognized figure in the field of chemical engineering, particularly known for her contributions to the understanding of fluid dynamics and multiphase flow. She has been involved in research that focuses on various aspects of thermodynamics and transport processes, often using advanced modeling techniques to study complex systems. Additionally, she is recognized for her work in education, mentorship, and collaboration within the scientific community.
Electron-positron annihilation is a fundamental process in particle physics that occurs when an electron (a negatively charged subatomic particle) encounters its antiparticle, the positron (which has the same mass as the electron but a positive charge). When they meet, they can annihilate each other, resulting in the conversion of their mass into energy, typically in the form of photons (gamma rays).
VistA Imaging is a component of the Veterans Health Information Systems and Technology Architecture (VistA), which is the electronic health record system used by the U.S. Department of Veterans Affairs (VA). VistA Imaging specifically focuses on the management, storage, and retrieval of medical images and related data.
90Y-DOTA-biotin is a radiopharmaceutical compound that combines the radioactive isotope Yttrium-90 (90Y) with a chelating agent known as DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) and biotin.
Yttrium (90Y) clivatuzumab tetraxetan is a radiolabeled monoclonal antibody that is used in targeted radiation therapy, specifically for the treatment of certain types of cancer. Here's a breakdown of its components: 1. **Yttrium-90 (90Y)**: This is a radioactive isotope of yttrium. It emits beta radiation, which can be used to destroy cancer cells in targeted therapy.
The Uranium Information Centre (UIC) is an organization based in Australia that was established to provide accurate information about uranium and its use, particularly in relation to nuclear energy. The center serves as a resource for the public, government, industry, and media, offering insights into various aspects of uranium, including its mining, processing, safety, environmental impact, and role in energy production.
Women and Families for Defence is an organization that typically focuses on supporting women and families impacted by armed conflict and military service. While there may be various organizations with similar names, many of them aim to advocate for the rights and well-being of women and family members of military personnel. They often engage in activities such as providing resources, offering support services, and advocating for policy changes that address the unique challenges faced by these groups.
UCL Australia is a campus of University College London (UCL) located in Adelaide, South Australia. It was established to provide high-quality education and research opportunities, particularly in engineering, computer science, and related fields. UCL Australia focuses on leveraging collaboration with local industries and research institutions, aiming to contribute to the educational and technological landscape of the region. UCL is one of the leading research universities globally, and its Australian campus aims to extend its impact and offerings beyond the UK.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact