DNA-binding proteins are a type of protein that have the ability to bind to DNA molecules, typically influencing DNA structure, function, and regulation. These proteins play crucial roles in various biological processes, such as: 1. **Gene Regulation**: Many DNA-binding proteins, including transcription factors, can enhance or inhibit the transcription of specific genes by binding to promoter or enhancer regions.
Davydov soliton by Wikipedia Bot 0
A Davydov soliton is a type of soliton, or solitary wave, that is found in certain dissipative systems, particularly in the context of biological systems and biophysics. It is named after the Russian physicist A. S. Davydov, who proposed its existence in the context of the behavior of proteins, specifically the α-helix structures of proteins.
Lipid bilayer fusion is a biological process in which two lipid bilayers merge to form a single, continuous bilayer. This phenomenon is crucial for many cellular processes, including membrane transport, signal transduction, and the fusion of vesicles with target membranes—such as during neurotransmitter release at synapses, hormone secretion, and viral entry into host cells. The process involves several steps: 1. **Approach**: Two lipid bilayers come into proximity.
New Criticism by Wikipedia Bot 0
New Criticism is a literary theory and approach to reading and interpreting texts that emerged in the early to mid-20th century, primarily in the United States. It emphasizes close reading, focusing on the text itself rather than external factors such as the author's intentions, historical context, or biographical details. Key principles of New Criticism include: 1. **Textual Unity**: New Critics believe that a literary work should be analyzed as a self-contained entity.
Magnetomyography by Wikipedia Bot 0
Magnetomyography (MMG) is a neurophysiological measurement technique that records the magnetic fields produced by electrical activity in muscles. It is analogous to electromyography (EMG), which measures the electrical activity of muscles through the use of electrodes placed on the skin. However, while EMG measures electrical signals directly, MMG captures the magnetic fields generated by those electrical signals.
Oncotherm by Wikipedia Bot 0
Oncotherm is a medical technology company that specializes in the development of innovative cancer treatment solutions. The company is known for its focus on hyperthermia therapy, which involves the use of controlled heat to treat tumors and cancerous tissues. Hyperthermia is based on the principle that elevated temperatures can enhance the effectiveness of traditional cancer treatments, such as chemotherapy and radiation, by improving drug delivery and disrupting cancer cell function.
Physical oncology by Wikipedia Bot 0
Physical oncology is an interdisciplinary field that combines principles from physics, oncology (the study and treatment of cancer), biomedical engineering, and other related sciences to better understand cancer and improve its treatment. The aim of physical oncology is to apply physical concepts and techniques to the challenges associated with cancer diagnosis, treatment, and research.
Tethered particle motion (TPM) is a biophysical technique used to study molecular interactions, conformational changes, and dynamics at the single-molecule level. In TPM experiments, a biomolecule (such as DNA, RNA, or a protein) is typically attached (or "tethered") to a surface via one end while the other end is labeled with a fluorescent particle, usually a microsphere or quantum dot.
Random coil index by Wikipedia Bot 0
The Random Coil Index (RCI) is a quantitative measure used to describe the intrinsic conformational properties of polypeptides or proteins in solution, particularly the propensity of certain amino acid sequences to adopt random coil (or disordered) conformations. It provides insights into the structural characteristics of proteins that do not have a well-defined three-dimensional structure, often referred to as intrinsically disordered proteins (IDPs) or regions within proteins.
Oceanography by Wikipedia Bot 0
Oceanography is the scientific study of the ocean, encompassing a diverse range of topics and disciplines. It seeks to understand the physical, chemical, biological, and geological aspects of the ocean and its interactions with the atmosphere and the Earth's landmasses. Oceanography can be broadly divided into several sub-disciplines: 1. **Physical Oceanography**: This subfield focuses on the physical properties of the ocean, including currents, waves, tides, and the ocean's role in climate regulation.
Scott Aaronson by Wikipedia Bot 0
Scott Aaronson is a prominent theoretical computer scientist known for his work in quantum computing, computational complexity theory, and algorithms. He is a professor at the University of Texas at Austin and has contributed significantly to the understanding of the power and limitations of quantum computers. Aaronson is also known for his ability to communicate complex scientific concepts to a broader audience, including through his popular blog "Shtetl-Optimized," where he discusses topics related to computer science, physics, and philosophy.
Stathis Zachos by Wikipedia Bot 0
Stathis Zachos is not widely recognized in mainstream media or popular culture. It's possible that he could be a private individual, an emerging figure, or someone known in a specific niche or regional context.
Susanne Albers by Wikipedia Bot 0
Susanne Albers is a notable figure in the field of computer science, particularly recognized for her work in algorithms and data structures. She has made significant contributions to areas such as online algorithms, competitive analysis, and the design of efficient algorithms for various computational problems. As an academic, she has published numerous papers and has been involved in various educational initiatives.
Toniann Pitassi by Wikipedia Bot 0
Toniann Pitassi is a prominent figure in the field of computer science, particularly known for her work in computational complexity theory. She is a professor at the University of Toronto and has made significant contributions to understanding the relationships between various complexity classes and the power of different proof systems. Her research often intersects with topics like model theory, mathematical logic, and algorithmic game theory.
Vijay Vazirani by Wikipedia Bot 0
Vijay Vazirani is a prominent computer scientist and professor known for his contributions to theoretical computer science, specifically in areas such as algorithms, combinatorial optimization, and game theory. He is a faculty member at the Georgia Institute of Technology and has published numerous papers in these fields. His work often addresses complex problems in computer science, and he is known for his innovative approaches to designing efficient algorithms.
Computational complexity theory is a branch of theoretical computer science that studies the resources required for solving computational problems. The primary focus is on classifying problems according to their inherent difficulty and understanding the limits of what can be computed efficiently. Here are some key concepts and elements of computational complexity theory: 1. **Complexity Classes**: Problems are grouped into complexity classes based on the resources needed to solve them, primarily time and space.
Admissible numbering is a concept from recursion theory and mathematical logic, particularly in the study of computability and computable structures. An admissible numbering is a way of assigning natural numbers to objects in such a way that the properties and relationships of these objects can be effectively worked with or analyzed. More specifically, an admissible numbering is a type of coding that provides a systematic method to index or enumerate certain sets or classes of objects, typically in recursion theory or the theory of computable functions.
Busy beaver by Wikipedia Bot 0
The "Busy Beaver" is a concept in computability theory and theoretical computer science that relates to Turing machines, which are abstract mathematical models of computation. The Busy Beaver function, often denoted as \( BB(n) \), is defined for a Turing machine with \( n \) states that halts on all possible inputs. The function gives the maximum number of non-blank symbols that such a Turing machine can output before halting.

Pinned article: ourbigbook/introduction-to-the-ourbigbook-project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact