Ciro Santilli @cirosantilli 40

Kind of the opposite of a basal group.

It is good to see that top-universities is still keeping up with it's main purpose: spontaneous eugenics:

This technique has managed to determine protein 3D structures for proteins that people were not able to crystallize for X-ray crystallography.

It is said however that cryoEM is even fiddlier than X-ray crystallography, so it is mostly attempted if crystallization attempts fail.

By looking at Figure 1. "A cryoEM image", you can easily understand the basics of cryoEM.

We just put a gazillion copies of our molecule of interest in a solution, and then image all of them in the frozen water.

Each one of them appears in the image in a random rotated view, so given enough of those point of view images, we can deduce the entire 3D structure of the molecule.

Ciro Santilli once watched a talk by Richard Henderson about cryoEM circa 2020, where he mentioned that he witnessed some students in the 1980's going to Germany, and coming into contact with early cryoEM. And when they came back, they just told their principal investigator: "I'm going to drop my PhD theme and focus exclusively on cryoEM". That's how hot the cryo thing was! So cool.

Very good open source book: github.com/csound-flossmanual/csound-floss

Includes introduction to the basic sound synthesis and their implementation in Csound.

Examples run on browser via Emscripten and just worked on Ubuntu 20.04!

Examples can also be downloaded all at once from: www.csound-tutorial.net/floss_manual/ Shame not in Git as standalone files.

flossmanual.csound.com/sound-synthesis/subtractive-synthesis covers Minimoog-like subtractive synthesis.

Other examples include:

That example calculates and displays the final widths via JavaScript, making it easier to understand the calculations being done.

Answers: stackoverflow.com/questions/28473807/how-does-flex-grow0-get-interpreted/69995712#69995712

Bibliography:

A fast version of a somewhat subset of csvkit, written in C.

Build failed with undefined reference to pcre_config on Ubuntu 23.04: github.com/DavyLandman/csvtools/issues/18

Unfortunately it is lacking some basic options, like optional header + selecting column by index on csvgrep (though csvcut has it). The project seems kind of dead.

Also unclear if it allows to filter + print only selected columns.

Lit. "to kick (leather) ball".

Figures notbaly in Water Margin, where it is played by Gao Qiu. The novel also suggests that it was considered a lesser art, e.g. as opposed to the scholarly four arts and the "proper" martial arts.

As mentioned at: cirosantilli.com/china-dictatorship/falun-gong#christine-marie Ciro Santilli considers this a synonym for "Prophet".

The porn version of Crushbridge, died in 2020.