E. Coli K-12 MG1655 gene of unknown function Updated +Created
UniProt for example describes YaaX as "Uncharacterized protein YaaX".
As function is discovered, they then change it to a better name, e.g. to names such as the E. Coli K-12 MG1655 transcription unit thrLABC proteins all of which have a clear name due to threonine.
There are many other y??? as of 2021! Though they do tend to be smaller molecules.
Haascope Updated +Created
By Andy Haas, an experimental particle physics professor: as.nyu.edu/content/nyu-as/as/faculty/andy-haas.html What an awesome dude!
Video 1.
Haasoscope prototype, 2 4-channel boards
. Source.
ScopeFun Updated +Created
899 USD as of 2022, takes a year to ship as they gather up a lot of orders before producing.
Sounds so cool, especially the multi functionality. Shame so expensive.
Sun Microsystems Updated +Created
Although Ciro Santilli is a bit past their era, there's an aura of technical excellence about those people. It just seems that they sucked at business. Those open source hippies. Erm, wait.
Bibliography:
Video 1.
The Dawn and Dusk of Sun Microsystems by Asianometry (2022)
Source. One of the main inspirations for the creation of their workstations were CAD applications.
Value function Updated +Created
The function being maximized in a optimization problem.
Subtle is the Lord by Abraham Pais (1982) Updated +Created
Chappe telegraph Updated +Created
Sum of three cubes Updated +Created
Compared to Waring's problem, this is potentially much harder, as we can go infinitely negative in our attempts, there isn't a bound on how many tries we can have for each number.
In other words, it is unlikely to have a Conjecture reduction to a halting problem.
Video 1.
3 as the sum of the 3 cubes by Numberphile (2019)
Source.
Silk Road (marketplace) Updated +Created
Ciro Santilli has become slightly obsessed with this story, and the main mastermind Ross Ulbricht.
Figure 1.
Ross Ulbricht's open laptop shortly after his arrest at the Francisco Public Library
. Source. He was running some GNOME based distro, could be Ubuntu from that photo, and likely is given that Ross once recommended Ubuntu to his flatmate.
The best article available so far is: www.theregister.co.uk/2019/01/29/how_i_caught_silk_road_mastermind (archive) which summarizes what one of the investigators said in a 2019 French computer security conference.
The key living posts are:
The big question is of course how libertarian free market ideologically motivated the website was, and how purely criminal greed it was.
The magnitude of the early operational security mistakes does make Ciro think that Ross did it "because he could" and "for the lolz" in a real world Breaking Bad way.
[i]n 2011," [I believe I will be] "creating a year of prosperity and power beyond what I have ever experienced before,
Silk Road is going to become a phenomenon and at least one person will tell me about it, unknowing that I was its creator."
Having this kind of feeling, is the greatest thing any human can have, and what motivates all great things.
Capitalizing in illegal things though is a cheat, big things take longer than a few years to reach, but reaching them is that much more satisfying as well.
Other interesting quotes:
I hated working for someone else and trading my time for money with no investment in myself.
which Ciro also feels, see don't be a pussy, and:
Everyone knows I am working on a bitcoin exchange. I always thought honesty was the best policy and now I didn't know what to do. I should have just told everyone I am a freelance programmer or something, but I had to tell half truths. It felt wrong to lie completely so I tried to tell the truth without revealing the bad part, but now I am in a jam. Everyone knows too much. Dammit.
The murder for hire allegations are also interesting: mashable.com/2013/10/03/silk-road-hits, he paid 80k dollars to undercover DEA agents!
Except for the fact that Ross was an 80 million Dollar drug lord, those accounts sound exactly like what you would expect from any other nerdy startup founder! The:
  • "just do it" strategy effectively going to a minimal viable product (manual transaction management!), while making many mistakes along the way, including hiring mistakes and successes when scaling is needed
  • the hardship of self bootstrapping your own social network (here with some kilos of mushrooms)
  • the variety of periods, from relatively calm, to hair pulling stress during big changes
It is also amusing to see very concretely the obvious fact that the FBI can get a subpoena for all accounts you ever had, e.g. they knew his laptop model from Amazon and brought a corresponding power cable to the arrest! If you are going to be a cyber criminal, don't use your real name, ever!
Should justice be blind? Maybe. But it does hurt for mere non-blind men to see it sometimes. Especially when drug liberalization is involved.
Video 1.
One Mistake Took Down a 29-Yr-Old Dark Web Drug Lord by Newsthink (2022)
Source. Wow nice video, covers most of the interesting annecdotes and the (alledged) investigation procedure.
Stored procedure Updated +Created
Sun Erniang Updated +Created
Erniang is way more popular than her ranking in the 108 Stars of Destiny.
This is of course in part because she is one of the only 3 108 Stars of Destiny women. But her story about making human mantou is particularly fun!
She's also quite seductive, which gives directors a good opportunity for a bit of fan service. See e.g. kknews.cc/history/6epp2pp.html for a still from The Water Margin showing some good cleavage for example.
Base calling Updated +Created
Bitcoin mining reward Updated +Created
Brain simulation Updated +Created
Change (Bitcoin) Updated +Created
Cryogen-free dilution refrigerator Updated +Created
Dilution refrigerator manufacturer Updated +Created
Eating Updated +Created

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