Process Simulation Software FREE Download - Aspen Hysys versus DWSim | COCO by Jeferson Costa (2020)
Source. Jeferson, a Brazilian from Petrobras, is the creator of the open source DWSim software, and in this video he gives a quick demo of his software and compares it briefly to aspen HYSYS, which appears to be the golden paid reference implementation.A cool thought about cancer expressed at Power, Sex, Suicide by Nick Lane (2006) is that cancer it is the direct product of natural selection gone wrong!
Cancer cells are obviously selected against anti-cancer mechanism, which when they manage to evade, they reproduce uncontrollably, gaining more and more momentum.
Sequence alignment is trying to match a DNA or amino acid sequence, even though the sequences might not be exactly the same, otherwise it would be a straight up string-search algorithm.
This is fundamental in bioinformatics for two reasons:
- when you sequence the DNA of a new species, you can guess what each protein does by comparing it with similar proteins in other species that you have already studied
- when doing DNA sequencing, and specially short-read DNA sequencing, you generally need to align the reads to reference genomes to know where you are inside the entire genome, and then be able to spot mutations, notably single-nucleotide polymorphisms
Small microscopic visible particles move randomly around in water.
If water were continuous, this shouldn't happen. Therefore this serves as one important evidence of atomic theory.
The amount it moves also quantitatively matches with the expected properties of water and the floating particles, was was settled in 1905 by Einstein at: investigations on the theory of the Brownian movement by Einstein (1905).
This suggestion that Brownian motion comes from the movement of atoms had been made much before Einstein however, and passed tortuous discussions. Subtle is the Lord by Abraham Pais (1982) page 93 explains it well. There had already been infinite discussion on possible causes of those movements besides atomic theory, and many ideas were rejected as incompatible with observations:The first suggestions of atomic theory were from the 1860s.
Further investigations eliminated such causes as temperature gradients, mechanical disturbances, capillary actions, irradiation of the liquid (as long as the resulting temperature increase can be neglected), and the presence of convection currents within the liquid.
Tiny uniform plastic beads called "microbeads" are the preferred 2019 modern method of doing this: en.wikipedia.org/wiki/Microbead
Original well known observation in 1827 by Brown, with further experiments and interpretation in 1908 by Jean Baptiste Perrin. Possible precursor observation in 1785 by Jan Ingenhousz, not sure why he wasn't credited better.
Observing Brownian motion of micro beads by Forrest Charnock (2016)
Source. - www.youtube.com/channel/UCM2YmsRUeIbRkqjgNm0eTGQ Journeyman Pictures. Basically a VICE-like, focused on fucked-up things happening in poor countries or regions.
- Mediocre Amateur
- 1958: myoglobin structure resolution (1958). The first protein to be resolved.
- 1965: lysozyme structure resolution (1965). The second protein to be resolved.
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