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Hyungwon Choi develops computational methods and methods in statistics for high-dimensional molecular data. His research includes integrating measurements from proteomics and metabolomics, extracting signals from mass spectrometry, and estimating regularized regression and graphical models. These problems connect a physical measurement instrument to statistical inference: many measured signals must be compared while accounting for noise and dependence. The National University of Singapore profile identifies this biomedical and computational research focus.[ref]
Portrait of Hyungwon Choi
. Photograph linked by the institutional NUS Graduate School profile; photographer and licence are not asserted. Source.Swapan Mallick is a researcher associated with human population genetics and genome-scale data resources. He is first author of The Simons Genome Diversity Project: 300 genomes from 142 diverse populations by Swapan Mallick and others, a resource for studying shared ancestry, biological population differences and demographic history. Sampling many biological populations increases the range of histories represented; it does not make the sample an exhaustive inventory of all human variation. [ref]
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations by Swapan Mallick and others. 2016, project design, sequencing and population sampling
Luca Pagani is a researcher in molecular anthropology and human population genomics. His work uses present-day and Ancient DNA to investigate biological population history, interactions between modern and archaic humans, and variation within contemporary biological populations. Comparing alternative histories with genomic data helps distinguish shared ancestry from later gene flow. [ref]
Richard E. Green is a researcher in genomics and human evolutionary genetics. He led A draft sequence of the Neandertal genome by Richard E. Green and others, which used ancient sequence data to investigate relationships between Neanderthals and present-day humans. His research also includes genome assembly and sequencing methods, connecting recovery of molecular information to inference about biological population history. [ref]
https://directory.ucsc.edu/cd_detail?guid=G016508286. UC Santa Cruz institutional profile, research interests
Aaron P. Ragsdale is a population geneticist who develops and applies models connecting demographic history to genetic variation. A weakly structured stem for human origins in Africa by Aaron P. Ragsdale and others evaluates histories with long-lived structure and continuing exchange rather than treating all ancestral biological populations as completely isolated branches. This connects mathematical model choice to the interpretation of human ancestry. [ref]
https://apragsdale.github.io/2_people.html. Laboratory biography: evolutionary and historical processes shaping variation
Iosif Lazaridis is a population geneticist studying human history with Ancient DNA. Ancient human genomes suggest three ancestral populations for present-day Europeans by Iosif Lazaridis and others compared ancient and present-day genetic data to model distinct ancestry contributions. The result illustrates why a biological population’s history can require genetic admixture rather than a single branching tree. [ref]
https://reich.hms.harvard.edu/people/iosif-lazaridis. Institutional laboratory profile
Iosif Lazaridis, institutional laboratory portrait
. Wolfgang Haak is a researcher in Ancient DNA and population genetics, studying the ancestry and movement of past human biological populations. Massive migration from the steppe was a source for Indo-European languages in Europe by Wolfgang Haak and others used genome-wide data to identify a major ancestry change in prehistoric Europe. Genetic ancestry provides evidence about biological population history, while the linguistic interpretation additionally depends on archaeological and linguistic context. [ref]
https://www.eva.mpg.de/de/archaeogenetics/staff/wolfgang-haak/. Institutional biography and research appointments
Wolfgang Haak, Max Planck Institute portrait
. Iain Mathieson is a population geneticist who studies human variation, demographic history and natural selection. His work combines modern and Ancient DNA to investigate how ancestry and selection shape observed variation. In Genome-wide patterns of selection in 230 ancient Eurasians by Iain Mathieson and others, changes across sampled past biological populations help separate historical allele-frequency patterns from a present-day snapshot. [ref]
https://mathii.github.io/. Personal research account: human population history, complex traits and selection
Iain Mathieson, institutional laboratory portrait
. Researcher in immune-cell migration. Lämmermann and collaborators investigated rapid leukocyte movement through flowing and squeezing without obligatory integrin adhesion, connecting cell mechanics with movement through confined tissue.[ref]
Rapid leukocyte migration by integrin-independent flowing and squeezing by Tim Lämmermann and others. Author list and described study
Researcher connecting immunology and nervous-system function. Filiano and collaborators investigated a role for interferon-gamma in neuronal connectivity and social behavior, testing how an immune signal can affect interactions among neurons.[ref]
Dan McKenzie and Carl Bowin used the spectral relation between Atlantic bathymetry and gravity to investigate how seafloor loads are supported. The method separates a topography-correlated signal from residual structure.[ref]
The relationship between bathymetry and gravity in the Atlantic Ocean by Dan McKenzie and Carl Bowin. Abstract: gravity/bathymetry filters and subsurface residuals
The wavelength dependence is useful because shallow loads, compensation and lithospheric flexure contribute differently across spatial scales. A single gravity anomaly does not isolate those contributions.
Carl Bowin and Dan McKenzie analysed ship-track gravity and bathymetry across the Atlantic. Treating the profiles spectrally lets a transfer relation predict part of the gravity signal from seafloor relief.[ref]
F. J. Vine and D. H. Matthews connected the pattern of marine magnetic stripes with spreading ocean floor and changing magnetic polarity. Their model relates a spatial magnetic sequence to the history carried away from a spreading ridge.[ref]
Magnetic Anomalies Over Oceanic Ridges by F. J. Vine and D. H. Matthews. 1963 paper: magnetic anomalies and ocean-floor spreading
D. H. Matthews and F. J. Vine proposed an explanation of marine magnetic anomalies that combines seafloor spreading with reversals of the geomagnetic field. Newly formed magnetized material moves away from a ridge, preserving a sequence of polarities.[ref]
Magnetic Anomalies Over Oceanic Ridges by F. J. Vine and D. H. Matthews. 1963 paper: spreading and magnetic-reversal interpretation
D. F. Argus coauthored a reconstruction of deglaciation using geodesy. GPS vertical motions help constrain regional ice-loss histories, and reference-frame choices enter the interpretation of these small secular movements.[ref]
Independent gravity and sea-level comparisons test whether the inferred ice and solid-Earth response work beyond the fitted observations.
R. Drummond coauthored the ICE-6G_C model of glacial isostatic adjustment. Station motions constrain former ice thickness and unloading, while time-dependent gravity and sea-level records test the resulting Earth response.[ref]
Space geodesy constrains ice age terminal deglaciation: The global ICE-6G_C (VM5a) model by W. R. Peltier and others. Abstract: geodetic refinement and independent validation
Adam M. Dziewonski and Don L. Anderson coauthored the Preliminary Reference Earth Model, a radial model constrained by body waves, free oscillations and global integral measurements.[ref]
Preliminary reference Earth model by Adam M. Dziewonski and Don L. Anderson. Abstract and Introduction: data combination and model construction
Combining these data constrains density and elastic properties more strongly than wave speeds alone. The result is a reference for comparing observations, rather than a claim that every location has identical structure.
Don L. Anderson and Adam M. Dziewonski constructed the Preliminary Reference Earth Model by jointly fitting seismic travel times, normal-mode observations, total mass and moment of inertia.[ref]
Preliminary reference Earth model by Adam M. Dziewonski and Don L. Anderson. Abstract: joint inversion and radial material properties
The model supplies mutually consistent reference profiles of elastic properties, density and attenuation. It also incorporates frequency dependence and upper-mantle anisotropy where required by the observations.
Jeanne L. Hardebeck coauthored a focal mechanism method that propagates uncertainty in first-motion polarity, source position and seismic structure. Synthetic tests and closely spaced earthquake groups provide checks on the inferred solutions.[ref]
A New Method for Determining First-Motion Focal Mechanisms by Jeanne L. Hardebeck and Peter M. Shearer. Abstract: uncertainty representation and validation
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact









