Topics (384k) Articles (398k) Users (410) Discussions (242) Comments (383) Files (13k) New article
Coauthor of the improved patch clamp methods paper. The work connected a high-resistance membrane seal with high-resolution recording from cells and isolated membrane patches, making small channel currents experimentally accessible.[ref]
Researcher in membrane electrophysiology. Neher and collaborators recorded currents from individual ion channels in muscle membranes, connecting discrete molecular openings with electrical signals measurable at the cell surface.[ref]
Portrait of Erwin Neher
. Molgen. Public domain (copyright holder release). Source usage terms, via Wikimedia Commons. Source.Coauthor of Assessing Insulin Sensitivity and Resistance in Humans. The chapter compares measurement approaches, connecting physiological questions about insulin resistance with the assumptions and limitations of experimental estimates.[ref]
Assessing Insulin Sensitivity and Resistance in Humans. Verified author or editor credit
Coauthor of Assessing Insulin Sensitivity and Resistance in Humans. The chapter compares measurement approaches, connecting physiological questions about insulin resistance with the assumptions and limitations of experimental estimates.[ref]
Assessing Insulin Sensitivity and Resistance in Humans. Verified author or editor credit
Coauthor of Assessing Insulin Sensitivity and Resistance in Humans. The chapter compares measurement approaches, connecting physiological questions about insulin resistance with the assumptions and limitations of experimental estimates.[ref]
Assessing Insulin Sensitivity and Resistance in Humans. Verified author or editor credit
Coauthor of the original glucose clamp technique paper. The method connected controlled glucose conditions with quantitative measurement of insulin secretion and resistance, helping separate two processes that affect an ordinary glucose response.[ref]
Coauthor of the original glucose clamp technique paper. The method connected controlled glucose conditions with quantitative measurement of insulin secretion and resistance, helping separate two processes that affect an ordinary glucose response.[ref]
Coauthor of the original glucose clamp technique paper. The method connected controlled glucose conditions with quantitative measurement of insulin secretion and resistance, helping separate two processes that affect an ordinary glucose response.[ref]
Coauthor of Introduction to Diabetes, connecting diabetes with the biological regulation of blood glucose. This is a documented authorship identification without an unsupported expansion of the credited initials.[ref]
Introduction to Diabetes. Verified author or editor credit
Coauthor of Introduction to Diabetes, connecting diabetes with the biological regulation of blood glucose. This is a documented authorship identification without an unsupported expansion of the credited initials.[ref]
Introduction to Diabetes. Verified author or editor credit
Researcher in metabolic signaling. Saltiel’s account of insulin signaling connects receptor-associated molecular pathways with their physiological functions and with changes associated with metabolic disease.[ref]
Insulin signaling in health and disease by Alan R. Saltiel. Author list and described study
Coauthor of Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships. The chapter connects the production and release of insulin with its molecular structure and biological activity.[ref]
Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships. Verified author or editor credit
Coauthor of Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships. The chapter connects the production and release of insulin with its molecular structure and biological activity.[ref]
Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships. Verified author or editor credit
Coauthor of Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships. The chapter connects the production and release of insulin with its molecular structure and biological activity.[ref]
Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships. Verified author or editor credit
Coauthor of experiments on glucagon signaling within pancreatic islets. The study connected communication among local endocrine cells with whole-organism glucose homeostasis, showing why a hormone’s role need not be limited to distant target tissues.[ref]
Intraislet glucagon signaling is critical for maintaining glucose homeostasis by Lu Zhu and others. Author list and described study
Coauthor of experiments on glucagon signaling within pancreatic islets. The study connected communication among local endocrine cells with whole-organism glucose homeostasis, showing why a hormone’s role need not be limited to distant target tissues.[ref]
Intraislet glucagon signaling is critical for maintaining glucose homeostasis by Lu Zhu and others. Author list and described study
Coauthor of experiments on glucagon signaling within pancreatic islets. The study connected communication among local endocrine cells with whole-organism glucose homeostasis, showing why a hormone’s role need not be limited to distant target tissues.[ref]
Intraislet glucagon signaling is critical for maintaining glucose homeostasis by Lu Zhu and others. Author list and described study
Coauthor of experiments on glucagon signaling within pancreatic islets. The study connected communication among local endocrine cells with whole-organism glucose homeostasis, showing why a hormone’s role need not be limited to distant target tissues.[ref]
Intraislet glucagon signaling is critical for maintaining glucose homeostasis by Lu Zhu and others. Author list and described study
Coauthor of experiments on glucagon signaling within pancreatic islets. The study connected communication among local endocrine cells with whole-organism glucose homeostasis, showing why a hormone’s role need not be limited to distant target tissues.[ref]
Intraislet glucagon signaling is critical for maintaining glucose homeostasis by Lu Zhu and others. Author list and described study
Coauthor of experiments on glucagon signaling within pancreatic islets. The study connected communication among local endocrine cells with whole-organism glucose homeostasis, showing why a hormone’s role need not be limited to distant target tissues.[ref]
Intraislet glucagon signaling is critical for maintaining glucose homeostasis by Lu Zhu and others. Author list and described study
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact