FOXP2 Created 2026-10-24 Updated 2026-11-05
The human gene encoding a transcription factor implicated in speech and language development through rare pathogenic variants. Related genes in other vertebrates provide mechanistic models, but the human phenotype is not equivalent to any single animal motor task. A gene-to-phenotype relationship does not by itself isolate one affected brain structure.[ref]
A forkhead-domain gene is mutated in a severe speech and language disorder by Cecilia S. L. Lai and others. Nature 413, 519–523; KE-family cosegregation and independent chromosome-translocation case
Frank Zamarripa Created 2026-10-13 Updated 2026-11-05
Gary F. Egan Created 2026-10-13 Updated 2026-11-05
Granule cell Created 2026-10-24 Updated 2026-11-05
A small neuron found in several brain regions. Cerebellar granule cells supply parallel fibers; dentate granule cells participate in sparse hippocampal input coding. These are anatomically distinct populations, so a shared descriptive name does not imply an identical circuit role.
Head injury Created 2026-10-31 Updated 2026-11-05
A head injury is trauma affecting structures of the head. Injury to the scalp or skull and injury to the brain are related but distinct possibilities; a visible external wound is not required for traumatic brain injury.
Concussion is one possible neurological consequence. The same observed confusion can also have other contributors, so its interpretation depends on the injury history and the wider examination.[ref]
Hemispatial neglect 2026-10-24
A disproportionate failure to attend or respond to events on one side of space, often contralesional to brain injury. It may affect external space, the body or internally generated scenes and can occur without an equivalent primary visual-field loss.[ref]
Unilateral Neglect of Representational Space by Edoardo Bisiach and others. 1978, imagined viewpoints and spatial omissions
Hippocampus Created 2026-10-24 Updated 2026-11-05
A brain structure involved in episodic memory and spatial processing. In computational accounts, dentate gyrus input transformation, recurrent hippocampal CA3 processing and hippocampal CA1 output processing supply complementary operations; these assignments are hypotheses constrained by recordings and interventions.
Hippocampus circuitry drawn by Santiago Ramón y Cajal, 1911
. Historical drawing of the rodent hippocampus by Santiago Ramón y Cajal, attributed on Commons to his Histologie du Système nerveux de l'Homme et des Vertébrés, Paris: A. Maloine, 1911. Public domain under the life-plus-70-year term recorded on Commons. This is an anatomical illustration, rather than a recording of episodic memory. Source usage terms. Source. H. Sugiyama Created 2026-10-13 Updated 2026-11-05
Coauthor of experiments expressing rat-brain messenger RNA in frog oocytes. Responses to neurotensin and acetylcholine connected experimentally supplied genetic information with measurable cellular signaling.[ref]
Hugo D. Critchley Created 2026-10-25 Updated 2026-11-05
A researcher who coauthored experiments relating heartbeat-timing performance to functional brain measurements. Combining a bodily signal with a perceptual task helped distinguish interoception from subjective confidence alone.[ref]
Neural systems supporting interoceptive awareness by Hugo D. Critchley and others. author contribution and study design
Research contributions include the primary work cited below.[ref]
https://pubmed.ncbi.nlm.nih.gov/14730305/. Identity and authorship record
Hypothalamus Created 2026-10-14 Updated 2026-11-05
The hypothalamus is a brain region integrating neural, autonomic and endocrine functions. It participates in regulation of temperature, fluid balance, feeding and biological timing. Distinct nuclei and pathways contribute, so naming the region alone does not identify one universal physiological controller.
Hypoxic-ischaemic brain injury Created 2026-10-31 Updated 2026-11-05
I. Ito Created 2026-10-13 Updated 2026-11-05
Coauthor of experiments expressing rat-brain messenger RNA in frog oocytes. Responses to neurotensin and acetylcholine connected experimentally supplied genetic information with measurable cellular signaling.[ref]
Intracranial haemorrhage Created 2026-10-31 Updated 2026-11-05
Intracranial pressure Created 2026-10-31 Updated 2026-11-05
Intracranial pressure is the pressure within the cranial compartment, commonly assessed through a specified fluid or tissue measurement. Brain tissue, blood and cerebrospinal fluid share a constrained space. Changes in their volumes and drainage therefore interact rather than acting as isolated pressures.
John Johnson Created 2026-10-13 Updated 2026-11-05
Justin S. Feinstein Created 2026-10-25 Updated 2026-11-05
Justin S. Feinstein studied fear and bodily signals in people with bilateral amygdala damage. A carbon-dioxide inhalation challenge investigated panic responses through a route different from viewing an external threat. Comparing these responses shows why a brain structure’s contribution must be specified for the stimulus and outcome being measured rather than summarized as the single location of all fear. [ref]
Fear and panic in humans with bilateral amygdala damage by Justin S. Feinstein and others. 2013, inhalation challenge and subjective panic responses
Kelly Macdonald Created 2026-10-24 Updated 2026-11-05
A researcher who studied endorsement of neuromyths among people with differing educational and neuroscience backgrounds. A survey compared beliefs in popular misconceptions with general brain knowledge. The design identifies patterns of association; group differences alone do not establish that training caused a particular individual to abandon a misconception.[ref]
Dispelling the myth: training in education or neuroscience decreases but does not eliminate beliefs in neuromyths by Kelly Macdonald and others. 2017, participant groups, survey and association analyses
Language 2026-10-24
Lateral ventricle 2026-11-05
A lateral ventricle is one of the two large cerebrospinal fluid-filled cavities within the cerebral hemispheres. Each connects with the third ventricle through an interventricular foramen. Its location inside a hemisphere makes it a useful landmark when interpreting sections or images of the brain.[ref]
Lateral Ventricles in MeSH. Definition, paired cerebral cavities and communication with the third ventricle
The choroid plexus projects into ventricular cavities and contributes to cerebrospinal fluid production; the ependyma lines the ventricular wall. The resulting environment joins a secretory interface, a fluid compartment and neighbouring neural tissue. These components have different roles even though they appear close together in an anatomical section.[ref]
Anatomy and Physiology 2e by J. Gordon Betts and others. §12.2, ependymal cells; §13.3, cerebrospinal fluid and choroid plexuses
The connections below provide a simplified route through the ventricular system. Actual transport also has a time dependence: phase-contrast magnetic resonance imaging has resolved cerebrospinal fluid movement over the cardiac cycle, while work on the third ventricle has revealed structured local flows driven by motile cilia.[ref]
Normal flow patterns of intracranial and spinal cerebrospinal fluid defined with phase-contrast cine MR imaging by D. R. Enzmann and others. abstract, cardiac-cycle-dependent flow encoding
[ref]Cilia-based flow network in the brain ventricles by Regina Faubel and others. abstract, ciliary modules and ventricular flow networks
Anatomical connections of the ventricular system
. Original schematic showing paired lateral ventricles, the interventricular foramina, third ventricle, cerebral aqueduct, fourth ventricle and subarachnoid spaces. Arrows follow the conventional passage sequence; cerebrospinal fluid also undergoes pulsatile movement and local recirculation.[ref]Neuroscience, 2nd edition edited by D. Purves and others. The Ventricular System, Figure 1.17, anatomical connections
Details. Liquefactive necrosis Created 2026-10-31 Updated 2026-11-05

