FOXP2 Created 2026-10-24 Updated 2026-11-05
The human gene encoding a transcription factor implicated in speech and language development through rare pathogenic variants. Related genes in other vertebrates provide mechanistic models, but the human phenotype is not equivalent to any single animal motor task. A gene-to-phenotype relationship does not by itself isolate one affected brain structure.[ref]
Frank Zamarripa Created 2026-10-13 Updated 2026-11-05
Coauthor of research on brain responses to skin warming and cooling. The study connected controlled thermal stimulation with regional signals measured by positron emission tomography in awake humans.[ref]
Gary F. Egan Created 2026-10-13 Updated 2026-11-05
Coauthor of research on brain responses to skin warming and cooling. The study connected controlled thermal stimulation with regional signals measured by positron emission tomography in awake humans.[ref]
Granule cell Created 2026-10-24 Updated 2026-11-05
A small neuron found in several brain regions. Cerebellar granule cells supply parallel fibers; dentate granule cells participate in sparse hippocampal input coding. These are anatomically distinct populations, so a shared descriptive name does not imply an identical circuit role.
Head injury Created 2026-10-31 Updated 2026-11-05
A head injury is trauma affecting structures of the head. Injury to the scalp or skull and injury to the brain are related but distinct possibilities; a visible external wound is not required for traumatic brain injury.
Concussion is one possible neurological consequence. The same observed confusion can also have other contributors, so its interpretation depends on the injury history and the wider examination.[ref]
Hemispatial neglect 2026-10-24
A disproportionate failure to attend or respond to events on one side of space, often contralesional to brain injury. It may affect external space, the body or internally generated scenes and can occur without an equivalent primary visual-field loss.[ref]
Hippocampus Created 2026-10-24 Updated 2026-11-05
A brain structure involved in episodic memory and spatial processing. In computational accounts, dentate gyrus input transformation, recurrent hippocampal CA3 processing and hippocampal CA1 output processing supply complementary operations; these assignments are hypotheses constrained by recordings and interventions.
Figure 1.
Hippocampus circuitry drawn by Santiago Ramón y Cajal, 1911
. Historical drawing of the rodent hippocampus by Santiago Ramón y Cajal, attributed on Commons to his Histologie du Système nerveux de l'Homme et des Vertébrés, Paris: A. Maloine, 1911. Public domain under the life-plus-70-year term recorded on Commons. This is an anatomical illustration, rather than a recording of episodic memory. Source usage terms. Source.
H. Sugiyama Created 2026-10-13 Updated 2026-11-05
Coauthor of experiments expressing rat-brain messenger RNA in frog oocytes. Responses to neurotensin and acetylcholine connected experimentally supplied genetic information with measurable cellular signaling.[ref]
Hugo D. Critchley Created 2026-10-25 Updated 2026-11-05
A researcher who coauthored experiments relating heartbeat-timing performance to functional brain measurements. Combining a bodily signal with a perceptual task helped distinguish interoception from subjective confidence alone.[ref]
Research contributions include the primary work cited below.[ref]
Hypothalamus Created 2026-10-14 Updated 2026-11-05
The hypothalamus is a brain region integrating neural, autonomic and endocrine functions. It participates in regulation of temperature, fluid balance, feeding and biological timing. Distinct nuclei and pathways contribute, so naming the region alone does not identify one universal physiological controller.
Hypoxic-ischaemic brain injury Created 2026-10-31 Updated 2026-11-05
Hypoxic-ischaemic brain injury is brain damage associated with inadequate oxygen supply and blood delivery. Supply, metabolic demand and duration interact. A loss of oxygenation and a loss of perfusion are related but distinct physiological disturbances.
I. Ito Created 2026-10-13 Updated 2026-11-05
Coauthor of experiments expressing rat-brain messenger RNA in frog oocytes. Responses to neurotensin and acetylcholine connected experimentally supplied genetic information with measurable cellular signaling.[ref]
Intracranial haemorrhage Created 2026-10-31 Updated 2026-11-05
Bleeding within the cranial cavity. The involved compartment—such as brain tissue or surrounding spaces—affects pressure, tissue injury and the interpretation of imaging.
Intracranial pressure Created 2026-10-31 Updated 2026-11-05
Intracranial pressure is the pressure within the cranial compartment, commonly assessed through a specified fluid or tissue measurement. Brain tissue, blood and cerebrospinal fluid share a constrained space. Changes in their volumes and drainage therefore interact rather than acting as isolated pressures.
John Johnson Created 2026-10-13 Updated 2026-11-05
Coauthor of research on brain responses to skin warming and cooling. The study connected controlled thermal stimulation with regional signals measured by positron emission tomography in awake humans.[ref]
Justin S. Feinstein Created 2026-10-25 Updated 2026-11-05
Justin S. Feinstein studied fear and bodily signals in people with bilateral amygdala damage. A carbon-dioxide inhalation challenge investigated panic responses through a route different from viewing an external threat. Comparing these responses shows why a brain structure’s contribution must be specified for the stimulus and outcome being measured rather than summarized as the single location of all fear. [ref]
Kelly Macdonald Created 2026-10-24 Updated 2026-11-05
A researcher who studied endorsement of neuromyths among people with differing educational and neuroscience backgrounds. A survey compared beliefs in popular misconceptions with general brain knowledge. The design identifies patterns of association; group differences alone do not establish that training caused a particular individual to abandon a misconception.[ref]
Language 2026-10-24
A system of structured representations and conventions supporting expression and interpretation. Its study distinguishes sound structure, grammatical organization and meaning without assuming that each maps one-to-one onto a single brain region.
Lateral ventricle 2026-11-05
A lateral ventricle is one of the two large cerebrospinal fluid-filled cavities within the cerebral hemispheres. Each connects with the third ventricle through an interventricular foramen. Its location inside a hemisphere makes it a useful landmark when interpreting sections or images of the brain.[ref]
The choroid plexus projects into ventricular cavities and contributes to cerebrospinal fluid production; the ependyma lines the ventricular wall. The resulting environment joins a secretory interface, a fluid compartment and neighbouring neural tissue. These components have different roles even though they appear close together in an anatomical section.[ref]
The connections below provide a simplified route through the ventricular system. Actual transport also has a time dependence: phase-contrast magnetic resonance imaging has resolved cerebrospinal fluid movement over the cardiac cycle, while work on the third ventricle has revealed structured local flows driven by motile cilia.[ref][ref]
Figure 1.
Anatomical connections of the ventricular system
. Original schematic showing paired lateral ventricles, the interventricular foramina, third ventricle, cerebral aqueduct, fourth ventricle and subarachnoid spaces. Arrows follow the conventional passage sequence; cerebrospinal fluid also undergoes pulsatile movement and local recirculation.[ref] Details.
Liquefactive necrosis Created 2026-10-31 Updated 2026-11-05
A pattern of necrosis in which tissue is digested into a fluid-like mass. It is characteristic of some infections and ischemic brain injury, connecting the final texture with degradation of the original structure.