Loss of methylated cytosines through active enzymatic replacement or through failed maintenance during replication.
A plant DNA glycosylase involved in reproductive epigenetic reprogramming and maternal imprinting effects.
A plant DNA glycosylase/lyase involved in active DNA demethylation through a repair-associated pathway.
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DNA demethylation is the process by which methyl groups are removed from the DNA molecule, specifically from the cytosine base in the context of DNA methylation. DNA methylation typically occurs at cytosine residues in the context of CpG dinucleotides and is a key epigenetic modification that can regulate gene expression. Methylation often leads to the silencing of gene expression, while demethylation can promote activation.