Original question.
Assuming the lungs to contain 1600 cubic centimetres of air at the termination of an expiration, and 400 cubic centimetres to be introduced by each inspiration, if, after an expiration a vertical tube be placed in the mouth, with its lower end dipping in mercury, and, the nose being stopped, the act of inspiration be performed, to what height will the mercury rise in the tube ? The height of the mercury in the barometer being 760 m.m., and the air in the tube being neglected.
Boyle's law states that a fixed amount of gas at constant temperature obeyswhere is absolute pressure, not gauge pressure. It is an ideal-gas approximation, not an assertion that every rapid compression is isothermal.
The respiratory diaphragm contracts and lowers its dome, increasing thoracic volume. Mechanical coupling through the pleural space lets the lungs expand; alveolar pressure falls below atmospheric pressure, drawing air in. Relaxation of the respiratory diaphragm and elastic recoil drive quiet expiration. These respiratory mechanics describe ventilation, distinct from chemical cellular respiration.[ref]
How the Lungs Work: What Breathing Does for the Body by the National Heart, Lung, and Blood Institute. “Breathing in” and “Breathing out”: diaphragm movement, expansion and recoil
For the stipulated sealed, isothermal gas, initial and final volumes are and . Expressing absolute pressure as a mercury-column height,The mercury column is supported by the atmospheric-to-internal pressure difference:The specified volume change belongs to the historical idealized model. Real tube-air volume, temperature changes and limits on respiratory-muscle pressure generation would affect a physical apparatus.
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