I would test whether the ancient farside crust grew locally with an early thermal/compositional gradient or acquired a substantial later accreted layer. The research programme should estimate a globally consistent crustal mass and chronology before tuning either mechanism to a single attractive map.
First, map crustal geometry with independent density constraints. Jointly invert GRAIL gravity and laser-altimeter surface topography, allowing spatially varying density and porosity rather than converting every anomaly to thickness. A new broad-band seismic network should include farside stations, long-lived polar power systems and a communications relay. Natural impacts and moonquakes, supplemented by calibrated active sources near landing sites, would constrain layer velocities, attenuation, crustal interfaces and the crust-mantle boundary. Crossing ray paths and receiver-side conversions are essential to distinguish a thick crust from an incorrect density or velocity assumption. A coherent buried layer or age-correlated discontinuity across the farside would favor addition or stacking; a gradual hemispheric compositional gradient would better support asymmetric local growth. Neither pattern is guaranteed to survive later impacts.
Second, obtain samples that address the initial contrast. Collect geographically distributed ancient highland rocks from both hemispheres, using basin ejecta, central peaks and drilling to sample beneath the impact-gardened regolith. Return samples with mapped geological context. Mineral chemistry and bulk Ca–Al–Mg–Fe abundances would test a primary refractory gradient; crystallization ages would date crustal construction, while shock-reset ages would date overprinting. Isotopic and trace-element measurements could identify an accreted population, but similar isotopes are possible for material derived from the same early debris system. A young deposit draped over older crust would favor accretion; coeval flotation-related crust with a systematic chemical gradient would favor local asymmetric differentiation. Multiple sites are necessary because a single basin's ejecta can mix distant sources.
Third, measure the thermal and volcanic consequences. Place shielded, sufficiently deep heat flow probes in representative highlands and mare terrains. Combine their geothermal gradients and measured thermal conductivity with orbital gamma-ray constraints on heat-producing elements. Map mare volumes and eruption ages, rather than only their exposed areas, to separate melt production from storage and eruption efficiency. A strong correlation between late volcanism, subsurface heat producers and high inferred mantle temperatures would support radiogenic amplification, while old crustal asymmetry without that correlation would show that later heating is not the entire cause.
Finally, compare forward models against withheld observations. Couple irradiation, vapor transport, condensation, lunar magma ocean mixing and crystallization for the thermal scenario; couple orbital evolution, impact deposition, mixing and later viscous relaxation for accretion. Account for later true polar wander before treating present-day hemispheric orientation as the original formation geometry. Require each model to conserve mass and energy and to reproduce the independent thickness, chemistry, age and volcanic data within their uncertainties. Vary unknown initial conditions and compare predicted observables at sites not used for calibration. The discriminating outcome is a conjunction such as a coherent accreted unit with a consistent emplacement age, or an ancient chemical gradient quantitatively consistent with transport under Earth irradiation. A lower gravity misfit alone cannot establish the historical mechanism, because gravity is a nonunique inverse problem.

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