A small GTPase is a relatively small nucleotide-switch protein that cycles between GDP- and GTP-bound states. Ras family proteins illustrate signaling mechanisms distinct from the three-subunit organization of a heterotrimeric G protein.
A small GTPase participating in protrusion and polarity in migrating cells.
A Rab-family regulator associated with late endosomal and degradative trafficking.
A Rab-family regulator associated with early endosomal membrane domains.
Replacement of an early Rab-regulated membrane identity by a later one, exemplified by Rab5 loss and Rab7 acquisition during endosome maturation.

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