A gene is a fundamental unit of heredity in living organisms. It is a segment of DNA (deoxyribonucleic acid) that contains the instructions necessary for the synthesis of proteins, which perform a wide range of functions in the body, including structural, regulatory, and enzymatic roles. Genes are organized along chromosomes, which are structures found in the nucleus of cells. Each gene has a specific location, known as a locus, on a chromosome and can vary in size.
The genetic code is a set of rules that defines how the information encoded in DNA or RNA sequences is translated into proteins, which are essential for the structure and function of living organisms. It is essentially the language of genetic information. Here are some key points about the genetic code: 1. **Codons**: The genetic code consists of sequences of three nucleotides, known as codons. Each codon corresponds to a specific amino acid or a stop signal during protein synthesis.
The Geniom RT Analyzer is a type of nucleic acid analysis tool used primarily in the field of molecular biology and genomics. Developed by companies such as Febit Biomed, the Geniom RT Analyzer is designed for high-throughput RNA analysis, including applications like gene expression profiling, microRNA analysis, and other RNA-related studies.
Glycoprotein 130 (gp130) is a transmembrane protein that serves as a signal transducing receptor for a variety of cytokines, particularly interleukin-6 (IL-6) family cytokines. It plays a crucial role in the immune response, inflammation, and hematopoiesis. gp130 is involved in multiple biological processes, including the regulation of cell growth, differentiation, and survival.
A human artificial chromosome (HAC) is a synthetic chromosome that can be engineered to carry human genes and other genetic elements. HACs are developed using a combination of human genomic DNA and other components to create a structure that mimics the key features of a natural chromosome.
Dollar voting is a concept in economics and consumer behavior that refers to the idea that consumers express their preferences and influence market outcomes through their spending decisions. Essentially, when individuals choose to spend their money on certain products or services, they are "voting" for those items with their dollars. The principle behind dollar voting suggests that the choices consumers make reflect their values, preferences, and priorities, which in turn signals to producers and businesses what to supply.
Hydrophilic Interaction Chromatography (HILIC) is a chromatographic technique primarily used for the separation and analysis of polar and hydrophilic compounds. It is particularly effective for separating small polar molecules, such as carbohydrates, amino acids, and other biomolecules that are not easily retained by traditional reversed-phase liquid chromatography (RPLC). ### Key Features of HILIC: 1. **Stationary Phase**: HILIC utilizes a stationary phase that is often composed of a polar material.
I-CreI is a type of homing endonuclease, which is a class of enzymes that recognize specific DNA sequences and induce double-strand breaks in DNA. It is derived from the bacterium *Chlamydia trachomatis* and is known for its ability to recognize and cleave a unique 29-base pair sequence in the genomic DNA of its target organisms.
An isoschizomer is a type of restriction enzyme that recognizes the same DNA sequence as another enzyme but may cut it at different sites within that sequence or have different activities. Essentially, both isoschizomers can target the same sequence for cleavage, but they may not necessarily produce the same DNA fragments when they cut.
MG-RAST (Metagenomics Rapid Annotations using Subsystems Technology) is a web-based platform designed for the analysis and annotation of metagenomic data. It provides researchers with tools to analyze complex microbial communities from environmental samples, such as soils, water, and human microbiomes. Key features of MG-RAST include: 1. **Data Submission and Storage**: Users can upload raw sequencing data to the platform, which provides secure storage for large datasets.
MICAD typically stands for "Management of Information for the Community: An Aided Decision" or can represent initiatives focusing on modern information technology applications in various fields. However, specific interpretations can vary depending on the context in which the term is used.
Mammalian-wide interspersed repeats (MIRs) are a class of genetic elements found in the genomes of mammals. They are a type of transposable element, specifically classified as short interspersed nuclear elements (SINEs). MIRs are thought to have originated from retrotransposition events and are characterized by their relatively short length, typically ranging from about 100 to 300 base pairs.
Molecular modeling is a computational technique used to represent and analyze the structure, properties, and behavior of molecules. It leverages a variety of computational methods and simulations to visualize molecular interactions and predict the effects of changes in molecular structure. Here are some key aspects of molecular modeling: 1. **Structural Representation**: Molecular modeling enables the construction of models for molecules, including atoms, bonds, and spatial arrangements.
A molecular probe is a chemical species that can bind to a specific target molecule to help identify, quantify, or visualize it. These probes are commonly used in various fields such as molecular biology, biochemistry, and medical diagnostics. There are several types of molecular probes, including: 1. **Fluorescent Probes**: These probes emit light when excited by specific wavelengths and are used to label molecules in live cells or tissues for imaging purposes.
NdeI is a type of restriction enzyme, which is a protein that can cut DNA at specific sites. It is a type II restriction endonuclease, meaning it recognizes a specific sequence of nucleotides in the DNA and cleaves it at that location. The recognition sequence for NdeI is 5'-CATATG-3', and it typically cuts between the C and A, producing sticky ends.
NlaIII is a restriction enzyme, which is an endonuclease that recognizes specific nucleotide sequences in DNA and cleaves the DNA at or near these sites. Specifically, NlaIII recognizes the palindromic sequence "G***C" and cuts between the G and C nucleotides, yielding specific DNA fragments. Restriction enzymes like NlaIII are widely used in molecular biology for cloning, DNA manipulation, and various genetic engineering applications.
A nucleotide is the basic building block of nucleic acids, which are essential molecules in living organisms. Nucleotides serve as the monomers that link together to form DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
PUC19 stands for the Pre-University Course (PUC) examination held in 2019 in certain Indian states, primarily Karnataka. It represents the final examination for students who have completed two years of pre-university education, typically after finishing their secondary school (10th grade). The PUC system is often a stepping stone for students moving on to undergraduate programs.
The Pho regulon is a set of genes in bacteria, particularly in *Escherichia coli* (E. coli) and other Gram-negative bacteria, that are regulated in response to phosphate availability. It plays a crucial role in how bacteria adapt to low phosphate conditions, which can be critical for their survival and growth in various environments. When phosphate levels are low, the Pho regulon is activated, leading to the transcription of genes involved in phosphate acquisition, transport, and metabolism.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 3. Visual Studio Code extension installation.Figure 4. Visual Studio Code extension tree navigation.Figure 5. Web editor. You can also edit articles on the Web editor without installing anything locally.Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





