Mothur is a software package designed for the analysis of microbial communities, particularly those defined by DNA sequence data from high-throughput sequencing technologies, such as 16S rRNA gene sequences. It was developed to provide a comprehensive and user-friendly tool for researchers studying microbial ecology and diversity. Key features of Mothur include: 1. **Versatility**: It supports various steps in the analysis pipeline, including data preprocessing (e.g.
A tiling array is a type of microarray used in genomics for the simultaneous analysis of many genes. This technology allows scientists to measure the expression levels of thousands of genes in a single experiment. Tiling arrays are specifically designed to cover the entire length of a gene or genomic region, providing a continuous representation across the target region rather than targeting specific genes or regions.
Yass is an open-source, SaaS (software as a service) framework designed primarily for building applications using the Python programming language. It provides a structured way to develop web applications, particularly emphasizing rapid development and deployment. Yass typically includes features such as user authentication, database integration, and API support, making it easier for developers to create scalable and maintainable applications.
Sergey Piletsky is a prominent scientist known for his work in the field of analytical chemistry and biochemistry. He is particularly recognized for his contributions to the development of molecularly imprinted polymers (MIPs), which are synthetic materials that can selectively bind specific molecules, making them useful in various applications such as drug delivery, sensors, and environmental monitoring. Piletsky's research has focused on improving the design and functionality of MIPs, as well as exploring their applications in various disciplines.
Computational creativity is an interdisciplinary field that explores the creative capabilities of computer systems and algorithms. It involves the study and development of computer programs that can generate novel and valuable ideas, concepts, artifacts, or solutions, typically associated with human-like creativity. Key aspects of computational creativity include: 1. **Algorithmic Creativity**: Developing algorithms that can produce creative outputs, such as poetry, artwork, music, or even scientific theories.
Community informatics is a field that focuses on the use of information and communication technologies (ICT) to support and empower communities. It emphasizes the relationship between technology and community development, aiming to enhance local practices, foster social connections, and address community needs. Here are some key aspects of community informatics: 1. **Empowerment**: Community informatics seeks to empower local communities by providing access to information, resources, and technologies.
The term "artificial intelligence arms race" refers to a competitive situation among nations, corporations, or groups to develop and deploy advanced artificial intelligence technologies at the fastest pace, often with military or strategic applications in mind. This race can involve a variety of AI technologies, including machine learning, autonomous systems, natural language processing, and others that have potential applications in defense, security, and international power dynamics.
Hydroinformatics is an interdisciplinary field that combines hydrology, computer science, and information technology to enhance the understanding, management, and decision-making processes related to water resources. It utilizes computational tools, models, and data analysis techniques to study and solve various problems associated with hydrological systems, including water quality, water supply, flood forecasting, and watershed management.
The Todd–Coxeter algorithm is a method used in group theory, specifically for computing the orbit and stabilizer of elements in a permutation group, and for finding a presentation of a group given by generators and relations. It's particularly useful in the study of finite groups and is often used in computational group theory.
Cover's theorem, often referred to in the context of information theory, particularly pertains to the capacity of channels and the concept of data compression and transmission. The most common reference is Cover's theorem on the capacity of discrete memoryless channels (DMC). The theorem essentially states that for a discrete memoryless channel, the maximum rate at which information can be reliably transmitted over the channel is given by the channel's capacity.
Probably Approximately Correct (PAC) learning is a framework in computational learning theory that formalizes the concept of learning from examples. Introduced by Leslie Valiant in 1984, PAC learning provides a mathematical foundation for understanding how well a learning algorithm can generalize from a finite set of training data to unseen data. ### Key Concepts: 1. **Hypothesis Space**: This is the set of all possible hypotheses (or models) that a learning algorithm can consider.
The FitzHugh-Nagumo model is a mathematical model used to describe the electrical activity of excitable cells, such as neurons and cardiac cells. It's a simplification of the more complex Hodgkin-Huxley model, which describes action potentials in neurons. The FitzHugh-Nagumo model captures the essential features of excitability and is often used in theoretical biology, neuroscience, and studying various types of wave phenomena in excitable media.
Brain-reading refers to the process of interpreting or decoding brain activity to infer thoughts, intentions, or mental states. This can be achieved through various techniques, most notably neuroimaging methods such as functional magnetic resonance imaging (fMRI), electroencephalography (EEG), and magnetoencephalography (MEG). Researchers use these technologies to analyze patterns of brain activity and correlate them with specific cognitive functions or responses.
The Spike Response Model (SRM) is a type of mathematical model used to describe the dynamics of neuron firing in response to various stimuli. It is particularly relevant in the field of computational neuroscience and serves as a framework for understanding how neurons process inputs and generate output spikes (action potentials). Here are some key characteristics of the Spike Response Model: 1. **Spike Generation**: The model focuses on the timing of spikes, which are the discrete events when a neuron emits an action potential.
The term "connectome" refers to a comprehensive map of the neural connections in the brain. It is analogous to a genome, which represents the complete set of genetic material in an organism. The connectome aims to detail the complex network of neurons and their synaptic connections, providing insight into how different brain regions communicate with one another.
The Hodgkin–Huxley model is a mathematical description of the electrical characteristics of excitable cells, particularly neurons. Developed in 1952 by Alan Hodgkin and Andrew Huxley, this model provides a detailed mechanism for understanding how action potentials (the rapid depolarization and repolarization of the neuronal membrane) are generated and propagated. ### Key Components of the Hodgkin–Huxley Model 1.
Maximally Informative Dimensions (MID) refers to a concept in the fields of data science and machine learning, particularly in the context of dimensionality reduction and feature selection. It focuses on identifying the dimensions (or features) of a dataset that provide the most useful information for a particular task, such as classification, regression, or clustering. The underlying idea of maximally informative dimensions is that not all dimensions in a dataset contribute equally to the predictive power or understanding of the data.
NeuronStudio is a software tool designed for the analysis and reconstruction of neural morphology, particularly for the study of neurons and their complex structures. It is commonly used in neurobiology and related fields to facilitate the visualization, examination, and quantification of neuron shapes and connections, aiding researchers in understanding the architecture and functional properties of neural networks.
ABC@Home is a program that was established by ABC Television Network to allow fans and viewers to engage with their favorite shows and provide feedback from the comfort of their homes. It typically involves activities such as viewing episodes, participating in surveys, and sometimes getting exclusive content or rewards in exchange for their feedback. Programs like this are often designed to gather audience insights, promote viewer loyalty, and enhance the overall television viewing experience.
Computational particle physics is a branch of physics that uses computational methods and algorithms to study and simulate the behavior of fundamental particles and their interactions. This field plays a crucial role in understanding the fundamental forces of nature, such as the electromagnetic, weak, and strong forces, as well as the phenomena predicted by particle physics theories, including the Standard Model and beyond.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 3. Visual Studio Code extension installation.Figure 4. Visual Studio Code extension tree navigation.Figure 5. Web editor. You can also edit articles on the Web editor without installing anything locally.Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





