CLCN3 is a gene that encodes a member of the chloride channel family, specifically a voltage-gated chloride channel. The protein produced by this gene is part of the CLC (chloride channel) family and plays a key role in maintaining ion homeostasis, regulating cell volume, and facilitating various physiological processes across different cell types. CLCN3 is located on chromosome 16 in humans and is expressed in various tissues, indicating its diverse functions.
Channelrhodopsin is a type of light-sensitive ion channel primarily derived from certain species of green algae. These proteins are important tools in the field of optogenetics, a technique that allows researchers to control neuronal activity using light. Channelrhodopsins function by changing conformation in response to light, typically blue or green wavelengths, which allows ions such as sodium or calcium to flow into the cell.
Bi-isotropic materials are materials that exhibit isotropic properties in both mechanical and electromagnetic contexts. In simpler terms, these materials have the same mechanical and electromagnetic characteristics regardless of the direction in which they are measured. In mechanical terms, an isotropic material has uniform properties in all directions. This means that its mechanical response (like stress, strain, stiffness, etc.) is the same no matter the orientation of the applied forces.
TRPP, or Transient Receptor Potential Polycystin, refers to a family of ion channels that play significant roles in various physiological processes. The two most notable members of this family are TRPP1 and TRPP2, which are integral to the function of the primary cilia in renal epithelial cells.
VDAC1, or Voltage-Dependent Anion Channel 1, is a protein that is primarily located in the outer mitochondrial membrane. It plays a crucial role in the regulation of mitochondrial metabolism and cellular homeostasis. VDAC1 is involved in the transport of ions and small metabolites across the mitochondrial membrane, facilitating the exchange of molecules such as ATP, ADP, and various metabolites between the mitochondria and the cytosol.
Bought: November 2023 during Black Friday sale for £1,323.00 to be Ciro Santilli's main personal laptop.
Six years after, and we are 2x on every key spec (except processor Hz ;-) at about 1/2 the price and 1/2 the weight (though smaller 14" screen for greater portability), so not bad! Customized to max out each hardware spec:
Specs:
- Processor: AMD Ryzen 7 PRO 7840U Processor (3.30 GHz up to 5.10 GHz)
- Graphic Card: Integrated GraphicsThe Ubuntu 23.10 "About system GUI describes its graphics as: Radeon 780M Graphics × 16, which e.g. www.techpowerup.com/gpu-specs/radeon-780m.c4020 documents as running the RDNA 3 microarchitecture.
- Operating System: No Operating System selected upgrade
- Operating System Language: No Operating System Language selected upgrade
- Microsoft Productivity Software: None
- Memory: 64 GB LPDDR5X-6400MHz (Soldered)selected upgrade. Specs at: www.lenovo.com/gb/en/p/accessories-and-software/memory-and-storage/memory-and-storage-hard-drives/4xb1d04758 quotes "64 Gbps", i.e. 8 GB/s.
dd count=1M if=/dev/zero of=tmpgives only 255 MB/s however. - Solid State Drive: 2 TB SSD M.2 2280 PCIe Gen4 Performance TLC Opalselected upgrade
- Display: 14" WUXGA (1920 x 1200), IPS, Anti-Glare, Touch, 45%NTSC, 300 nits, 60Hz
- Camera: 1080P FHD RGB/IR Hybrid with Microphone
- Color: Thunder Black
- Factory Color Calibration: No Factory Color Calibration
- Wireless: Qualcomm Wi-Fi 6E NFA725A 2x2 AX & Bluetooth® 5.1 or above
- Integrated Mobile Broadband: No Wireless WAN
- Ethernet: Wired Ethernet
- Near Field Communication: No NFC
- Fingerprint Reader: Fingerprint Reader
- Keyboard: Black - English (EU)selected upgrade
- Battery: 4 Cell Li-Polymer 52.5Whselected upgrade
- Power Cord: 65W USB-C Slim 90% PCC 3pin AC Adapter - UKselected upgrade
- Electronic Privacy Filter: No ePrivacy Filter
- Adobe Elements: None
- Adobe Acrobat: None
- Adobe Creative Cloud: None
- Security Software: None
- Cloud Security Software: No Cloud Security Software
- Warranty: 3 Year Courier or Carry-in
Identifiers:
- Ethernet MAC address: fc:5c:ee:24:fb:b4
- Wi-Fi MAC address: 04:7b:cb:cc:1b:10
Upon arrival:
Buy research:
- www.phoronix.com/review/thinkpad-p14s-gen4 says Ubuntu running fine
- Intel vs amd: the Intel ones could come with a discrete rtx A500 GPU. GPU likely makes laptop heavier and less power efficient. And both have basically the same benchmark which is crazy:So the only downside is not being able to run CUDA.
- thought about Yoga or other Ultrabook options, but 2x price at same specs, so nah...
Log:
2024-01-17: firmware update:Actually fixed performance mode: askubuntu.com/questions/604720/setting-to-high-performance/1343879#1343879
Vendor: LENOVO
Version: R2FET36W (1.16 )
Release Date: 10/24/2023Near Vertical Incidence Skywave (NVIS) is a radio communication technique that uses high-frequency (HF) radio waves to establish communication over relatively short distances, typically up to about 600 kilometers (373 miles). The technique involves transmitting radio signals at a near-vertical angle, which allows the signals to be reflected off the ionosphere back towards the Earth's surface, effectively facilitating local communication.
Scott Ritter is a former U.S. Marine Corps intelligence officer and a chief weapons inspector for the United Nations Special Commission (UNSCOM) in Iraq in the late 1990s. He is known for his controversial views on various military and geopolitical issues, particularly concerning Iraq and the possession of weapons of mass destruction (WMD).
Massoud Ali-Mohammadi was an Iranian physicist known for his work in the fields of particle physics and nuclear science. He was a professor at the University of Tehran and had been involved in various research projects. Tragically, he became widely known after he was assassinated in January 2010, an act that many believe was politically motivated and linked to his involvement in Iran's nuclear program. His death sparked international attention and raised concerns over the safety of scientists in politically sensitive environments.
Shahriar Rouhani is a name that may refer to an individual, but as of my last update, there was no widely recognized public figure or information specifically associated with that name. It is possible that the name could relate to someone in various fields such as academia, arts, politics, or science, but without additional context, it's difficult to provide a definitive answer. If you have a specific context or category in mind (e.g., literature, political science, etc.
The allegations of Iraqi mobile weapons laboratories refer to claims made by the U.S. government and some intelligence agencies prior to the 2003 invasion of Iraq. The accusations suggested that the Iraqi government, under President Saddam Hussein, possessed mobile biological weapons laboratories, which could be used to produce biological agents for warfare. These claims were prominently featured in presentations by U.S. officials, particularly by then-U.S. Secretary of State Colin Powell during a speech at the United Nations in February 2003.
Ahmed Chalabi (1944–2015) was an Iraqi politician and former banker who played a significant role in the political landscape of Iraq, particularly in the lead-up to the 2003 invasion by the United States. He was the chairman of the Iraqi National Congress (INC), an opposition group that sought to overthrow the regime of Saddam Hussein. Chalabi was a controversial figure, known for his advocacy of the U.S.
Khidir Hamza is not a widely recognized name in mainstream sources, literature, or media as of my last knowledge update in October 2023. However, names can refer to individuals, fictional characters, or concepts in various contexts.
ISO 31-4 is an international standard that was part of the ISO 31 series, which deals with physical quantities and units. Specifically, ISO 31-4 addresses the topic of "Thermodynamics". It provides definitions and recommendations for the units of measurement used in thermodynamics, such as temperature, heat, and energy.
Fractionation of carbon isotopes in oxygenic photosynthesis refers to the differential uptake and incorporation of carbon isotopes (\(^{12}C\) and \(^{13}C\)) by photosynthetic organisms, primarily plants and cyanobacteria, during the process of converting carbon dioxide (CO2) into organic carbon compounds using sunlight.
The optical theorem is a fundamental concept in quantum mechanics and particularly in the field of scattering theory. It establishes a relationship between the total cross section of a scattering process and the forward scattering amplitude. In more detail, the optical theorem states that the imaginary part of the forward scattering amplitude (the amplitude for scattering at an angle of zero) is proportional to the total cross section for that scattering process.
Nitrogen-15 tracing refers to a technique used in various fields, including biology, ecology, and environmental science, where the stable isotope nitrogen-15 (N-15) is tracked to study nitrogen cycling, plant nutrition, and ecosystem dynamics. Nitrogen-15 is a naturally occurring isotope of nitrogen, making up about 0.37% of all nitrogen in nature, while the more common isotope, nitrogen-14 (N-14), accounts for the majority.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 3. Visual Studio Code extension installation.Figure 4. Visual Studio Code extension tree navigation.Figure 5. Web editor. You can also edit articles on the Web editor without installing anything locally.Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





