Thomas Henry Havelock (1790–1857) was a British Army officer known for his role during the Indian Rebellion of 1857. He was particularly noted for his leadership in the recapture of Delhi and the relief of the besieged British garrison in Lucknow. Havelock's military career spanned several campaigns, but he gained fame for his effective command and quick actions during the uprising, where he successfully navigated difficult circumstances to perform notable military feats.
"Advanced Composite Materials" is a peer-reviewed scientific journal that focuses on the research and development of advanced composite materials. These materials typically consist of two or more constituent materials with significantly different physical or chemical properties that remain distinct at macroscopic scales. The combination often leads to enhanced properties such as increased strength, lower weight, improved durability, and better resistance to environmental factors.
A skew-symmetric graph, in the context of graph theory, refers to a special type of directed graph (digraph) that exhibits certain symmetrical properties in its edges.
Oleg Marichev is a distinguished Russian mathematician known for his contributions to both theoretical and applied mathematics. He has made significant advancements in areas such as functional analysis, operator theory, and mathematical statistics. Throughout his career, Marichev has published numerous research papers and has been involved in various academic and professional activities, including teaching and mentoring students in mathematics.
Arcady Zhukov is a name that may refer to multiple subjects, but in the context of popular culture or recent developments, it might not be widely recognized.
"Americana" generally refers to artifacts, traditions, and cultural elements that are characteristic of the United States, encompassing its history, folklore, and popular culture.
Interatomic potential refers to the energy associated with interactions between atoms in a material. It describes how atoms in a substance affect one another through various types of forces, such as ionic, covalent, and van der Waals interactions. These potentials are crucial in computational physics and chemistry, as they allow researchers to model and predict the behavior of materials at the atomic level.
As of 2019, the silicon industry is ending, and molecular biology technology is one of the most promising and growing field of engineering.
Figure 1.
42 years of microprocessor trend data by Karl Rupp
. Source. Only transistor count increases, which also pushes core counts up. But what you gonna do when atomic limits are reached? The separation between two silicon atoms is 0.23nm and 2019 technology is at 5nm scale.
Such advances could one day lead to both biological super-AGI and immortality.
Ciro Santilli is especially excited about DNA-related technologies, because DNA is the centerpiece of biology, and it is programmable.
First, during the 2000's, the cost of DNA sequencing fell to about 1000 USD per genome in the end of the 2010's: Figure 2. "Cost per genome vs Moore's law from 2000 to 2019", largely due to "Illumina's" technology.
The medical consequences of this revolution are still trickling down towards medical applications of 2019, inevitably, but somewhat slowly due to tight privacy control of medical records.
Figure 2.
Cost per genome vs Moore's law from 2000 to 2019
. Source.
Ciro Santilli predicts that when the 100 dollar mark is reached, every person of the First world will have their genome sequenced, and then medical applications will be closer at hand than ever.
But even 100 dollars is not enough. Sequencing power is like computing power: humankind can never have enough. Sequencing is not a one per person thing. For example, as of 2019 tumors are already being sequenced to help understand and treat them, and scientists/doctors will sequence as many tumor cells as budget allows.
Then, in the 2010's, CRISPR/Cas9 gene editing started opening up the way to actually modifying the genome that we could now see through sequencing.
What's next?
Ciro believes that the next step in the revolution could be could be: de novo DNA synthesis.
This technology could be the key to the one of the ultimate dream of biologists: cheap programmable biology with push-button organism bootstrap!
Just imagine this: at the comfort of your own garage, you take some model organism of interest, maybe start humble with Escherichia coli. Then you modify its DNA to your liking, and upload it to a 3D printer sized machine on your workbench, which automatically synthesizes the DNA, and injects into a bootstrapped cell.
You then make experiments to check if the modified cell achieves your desired new properties, e.g. production of some protein, and if not reiterate, just like a software engineer.
Of course, even if we were able to do the bootstrap, the debugging process then becomes key, as visibility is the key limitation of biology, maybe we need other cheap technologies to come in at that point.
This a place point we see the beauty of evolution the brightest: evolution does not require observability. But it also implies that if your changes to the organism make it less fit, then your mutation will also likely be lost. This has to be one of the considerations done when designing your organism.
Other cool topic include:
It's weird, cells feel a lot like embedded systems: small, complex, hard to observe, and profound.
Ciro is sad that by the time he dies, humanity won't have understood the human brain, maybe not even a measly Escherichia coli... Heck, even key molecular biology events are not yet fully understood, see e.g. transcription regulation.
One of the most exciting aspects of molecular biology technologies is their relatively low entry cost, compared for example to other areas such as fusion energy and quantum computing.
An X-ray machine is a medical imaging device that utilizes X-rays to create images of the inside of the body. X-rays are a form of electromagnetic radiation, similar to visible light but with much higher energy. The machine operates by directing X-ray beams towards the body, and as the rays pass through, they are absorbed in varying degrees by different tissues based on their density.
Ciro once told a friend that his ideal life would be to "just chill out and eat his bread in peace" (while also learning and teaching the sciences). Quote "Omar Khayyam's chill out quote" comes to mind. See also: Ciro Santilli's cheapness.
A kinetic scheme refers to a mathematical framework or model used to describe the behavior of a system's particles in terms of their individual trajectories, velocities, and interactions. This concept is often employed in fields like statistical mechanics, fluid dynamics, and kinetic theory. In more detail: 1. **Kinetic Theory of Gases**: In physics, the kinetic theory of gases explains the macroscopic properties of gases in terms of their microscopic constituents (the molecules) and their kinetic energy.
Arild Mentzoni does not appear to be a widely recognized figure or term based on my training data up until October 2023. If he is a person, he may not be notable enough to have widespread information available, or he could be a figure who emerged after that date.
Seven Sleepers' Day, also known as the Feast of the Seven Sleepers, is a Christian holiday celebrated in various traditions, primarily within the Western and Eastern Orthodox Churches. It commemorates the legend of the Seven Sleepers of Ephesus, a group of Christian youths who, according to tradition, fell asleep in a cave to escape persecution during the Roman Empire and awoke centuries later during the reign of Emperor Theodosius II.
Solar power forecasting refers to the process of predicting the amount of solar energy that will be generated by photovoltaic (PV) systems or solar thermal plants over a specific period, such as hours, days, or even weeks in advance. Accurate forecasting is essential for effective integration of solar power into the electricity grid, as it helps grid operators, utility companies, and energy markets manage supply and demand more efficiently.
Weather routing is a method used primarily in the maritime and aviation industries to optimize the path of a ship or aircraft based on current weather conditions and forecasts. It involves analyzing various meteorological data, including wind speed and direction, currents, temperature, and precipitation, to determine the most efficient and safe route for travel. The key objectives of weather routing include: 1. **Fuel Efficiency**: By avoiding adverse weather conditions such as strong headwinds or heavy seas, vessels can save fuel and reduce operational costs.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact