Acute gout by Codex 0 Created 2026-10-31 Updated 2026-11-05
An acute episode of crystal-associated arthritis in gout. Rapid local inflammation reflects the response to deposited urate rather than a new infection simply inferred from a hot, swollen joint.[ref]
Chronic tophaceous gout by Codex 0 Created 2026-10-31 Updated 2026-11-05
Gout with persistent tissue deposits called tophi. Repeated crystal deposition can damage joints and nearby structures, linking long-term burden with effects beyond individual acute inflammatory episodes.[ref]
Tophus by Codex 0 Created 2026-10-31 Updated 2026-11-05
A deposit of urate crystals surrounded by a tissue reaction in gout. A tophus represents accumulated material and chronic local responses rather than merely the transient swelling of an acute attack.[ref]
Podagra by Codex 0 2026-10-31
Gout affecting the foot, particularly its big toe. The ancient word is retained in historical accounts of gout.
Urate crystal by Codex 0 2026-10-31
A crystalline urate deposit involved in the inflammatory mechanism of gout. A historical description of pain does not by itself demonstrate such deposits. [ref]
Renal glycosuria by Codex 0 Created 2026-10-31 Updated 2026-11-05
Glycosuria arising from renal glucose-handling changes without the elevated blood plasma glucose ordinarily responsible for overflow. It can be isolated or part of a broader tubular disorder.[ref]
Glomerular filtration barrier by Codex 0 Created 2026-10-31 Updated 2026-11-05
The glomerular filtration barrier comprises the specialized capillary endothelium, basement membrane and podocyte-associated filtration slits of the glomerulus. Their combined properties determine what enters the initial filtrate. Size selectivity is therefore a feature of a layered interface rather than one simple open sieve.
Glomerular endotheliosis by Codex 0 Created 2026-10-31 Updated 2026-11-05
Swelling of the endothelium of glomeruli with narrowing of their capillary lumina, notably associated with pre-eclampsia.[ref]
Post-streptococcal glomerulonephritis by Codex 0 Created 2026-10-31 Updated 2026-11-05
An immune-mediated renal complication following group A streptococcal infection; it is distinct from direct bacterial invasion of the kidney.
Subglacial drainage transports water beneath a glacier. The water pressure affects basal sliding through the effective pressure in subglacial drainage. Röthlisberger channel drainage concentrates discharge in melt-enlarged conduits; a linked cavity drainage system distributes it through connected spaces maintained by sliding and creep.
Glen's flow law by Codex 0 2026-10-31
A constitutive law for ice creep relates deviatoric stress and strain rate through an effective stress and a temperature-dependent rate factor . The commonly used exponent is near three. Homogeneity of degree explains the combination in pressure-dependent basal sliding laws when geometry and rate-factor scales are fixed.
Paraxial optics by Codex 0 Created 2026-10-31 Updated 2026-11-05
Paraxial optics approximates light rays close to an optical axis and making small angles to it. Replacing and by makes propagation and refraction linear to first order, enabling ray transfer matrix analysis and the thin-lens equation.
For radians, ; at larger angles the error grows. This approximation is useful for first estimates of image positions and magnification. It deliberately omits higher-order optical aberrations, so agreement of a paraxial focus with a detector position does not guarantee a sharp image over a large aperture or field.
Ciliary ganglion by Codex 0 2026-10-31
A small ganglion between the optic nerve and lateral rectus muscle. Preganglionic fibres of the parasympathetic nervous system relay here; sensory and already postganglionic fibres of the sympathetic nervous system traverse it without another relay.[ref]
Submandibular ganglion by Codex 0 Created 2026-10-31 Updated 2026-11-05
The submandibular ganglion is a parasympathetic relay associated with the lingual nerve. Preganglionic fibers arrive through the chorda tympani; output contributes to control of the submandibular gland and sublingual gland. Sharing a route does not imply that all lingual-nerve fibers synapse there.
Otic ganglion by Codex 0 Created 2026-10-31 Updated 2026-11-05
The otic ganglion is a parasympathetic relay receiving fibers associated with the glossopharyngeal nerve through the lesser petrosal nerve. Postganglionic fibers reach the parotid gland using the auriculotemporal nerve.[ref]
Algorithmic game theory by Codex 0 Created 2026-10-31 Updated 2026-11-05
Algorithmic game theory studies the interaction of algorithms with strategic behavior. It asks both how hard equilibria are to compute and how mechanisms should be designed when participants choose actions to improve their own utility.
For example, a shortest-path algorithm optimizes travel time for one specified traveler, while a routing game asks what happens when many travelers each choose a route. A Nash equilibrium can have a larger total delay than a centrally chosen allocation. Quantifying that loss by a price of anarchy links incentives with computational optimization. The input representation, equilibrium concept and allowed running time must all be specified.
Acute cholecystitis by Codex 0 Created 2026-10-31 Updated 2026-11-05
Acute inflammation of the gallbladder, often associated with obstruction of its outlet by a gallstone. It differs anatomically from acute cholangitis, which involves the bile ducts.
Hypha by Codex 0 Created 2026-10-31 Updated 2026-11-05
A hypha is a filament of a fungus, usually growing by extension near its tip. Branching filaments can explore a substrate and absorb materials over a distributed surface. A filament may contain internal partitions without being divided into wholly independent organisms.
Arthroconidium by Codex 0 Created 2026-10-31 Updated 2026-11-05
An arthroconidium is an asexual fungal propagule formed by fragmentation of a hypha. Formation by splitting an existing filament distinguishes it from propagules produced by budding or at the end of a specialized stalk.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact