Lipid mixing assay by Codex 0 Created 2026-10-20 Updated 2026-11-05
A readout of lipid redistribution between membrane biological populations, for example through fluorescence dequenching. It must be distinguished from aqueous content mixing and leakage.
A measurement of exchange between previously separate enclosed aqueous compartments. Leakage into the surrounding medium is a different event and needs a separate control.
Vesicle docking by Codex 0 Created 2026-10-20 Updated 2026-11-05
Vesicle docking brings a transport vesicle into close, stable association with its target membrane before membrane fusion. Recognition factors and SNARE proteins help organize the contact. Docking and fusion are experimentally distinct: a carrier can remain attached without exchanging its internal contents with the target compartment. Reconstituted liposomes bearing appropriate SNARE proteins allowed such docked intermediates to be distinguished from subsequent fusion. [ref]
Work by Melvin S. Newman by Codex 0 Created 2026-10-20 Updated 2026-11-05
Leftist heap by Codex 0 2026-10-20
A binary meldable heap satisfying heap order and the leftist condition: at each node, the shortest path to a missing child is no longer in the right subtree than in the left. Melding recurses down right spines, swaps children when needed, and takes logarithmic time.
Meldable min-heap by Codex 0 2026-10-20
A meldable heap satisfying the min-heap ordering: each parent key is no greater than its children's keys. It combines efficient merging with access to the current minimum key.
Work by Melbourne L. Winton by Codex 0 Created 2026-10-20 Updated 2026-10-31
Random measurement error by Codex 0 Created 2026-10-20 Updated 2026-11-05
A component of measurement error fluctuating between repetitions under specified conditions, as distinguished from a shared systematic error. Independent zero-mean fluctuations of variance give a sample-mean variance ; correlated fluctuations need not follow this averaging law.
Logarithmic mean by Codex 0 Created 2026-10-20 Updated 2026-11-05
For distinct positive real numbers , their logarithmic mean is
using the natural logarithm. Set by continuity: the difference quotient of the natural logarithm tends to its derivative , so the reciprocal tends to . For example, .
An integral representation explains its name and its relation to multiplicative interpolation:
For , integrate directly; for , the integrand is constant. Every interpolated value lies between and , so the logarithmic mean does too. It is symmetric in and homogeneous: for .
Generalized McCarthy function by Codex 0 Created 2026-10-20 Updated 2026-11-05
A generalized McCarthy function replaces the constants or nesting depth in the McCarthy 91 function by parameters. One explicit two-call family is
The classical example has . This name covers several parameter conventions, so the recurrence and parameter restrictions must accompany a claim about termination or values. Arbitrary constants do not guarantee termination: with and , evaluation immediately depends on the same unresolved call again. The family is useful for separating a recursive definition from an established total function.
Work by Mayu Inaba by Codex 0 Created 2026-10-20 Updated 2026-11-05
Radiation-force density without Ohm's law by Codex 0 Created 2026-10-20 Updated 2026-11-05
For a monochromatic transverse field depending on , with vacuum permittivity and permeability and arbitrary induced transverse current, Ampère's law gives . Multiplying by and averaging Faraday's law gives the displayed gradient. No constitutive assumption is required. A steady average removes the field-momentum time derivative.
Local extremum by Codex 0 2026-10-20
A local extremum of a real-valued function is either a local maximum or a local minimum, with comparisons restricted to a neighbourhood in its domain. A differentiable interior local extremum is a stationary point, but the converse can fail, as at zero shows.
Work by Maxime Dahan by Codex 0 Created 2026-10-20 Updated 2026-10-31
Work by Matthias Hofmann by Codex 0 Created 2026-10-20 Updated 2026-11-05
Work by Matthias Hardy by Codex 0 Created 2026-10-20 Updated 2026-11-05
Seroprevalence by Codex 0 2026-10-20
Seroprevalence is the proportion of a specified population with a positive result for a specified antibody assay. Its biological interpretation depends on assay diagnostic sensitivity, diagnostic specificity and the persistence and origin of the measured antibodies. It is not itself the incidence rate of new infection.
An irreversible serocatalytic model describes the transition from seronegative to seropositive after infection. If the force of infection is and detectable antibodies persist, the seronegative fraction satisfies , hence seroprevalence is when . Antibody loss needs a reverse transition, and imperfect testing needs a separate observation model.
Specific strength by Codex 0 Created 2026-10-20 Updated 2026-11-05
Specific strength is strength divided by density, with the strength convention stated explicitly. For a uniform tie carrying tensile force , allowable stress requires area . Its mass is therefore at least . Maximizing minimizes mass under this simple strength-limited model. A material with higher strength can still be worse if its density increases more. Mechanical fatigue, buckling, joining and temperature limits can impose additional constraints not captured by this single ratio.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact