Epidermal Growth Factor by Stanley Cohen by Codex 0 Created 2026-10-13 Updated 2026-10-31
Nobel lecture delivered on 8 December 1986. The PDF hosting path does not identify the lecture publication date.
Cited passages: Cohen, Epidermal Growth Factor, printed p. 339: A-431 membrane aliquots, terminally labeled ATP, divalent ions and trichloroacetic acid-insoluble incorporation; printed p. 341, numbered observations 1–4: rapid activation, dephosphorylation, lack of soluble kinase release and anti-EGF reversal; printed p. 341: co-migration in the electrophoretic system and subsequent identification of tyrosine phosphorylation.
Published in Cell.
Cited passages: Lemmon and Schlessinger, “Mechanisms of Receptor Activation” and “Allosteric activation of TKDs”, Figure 2F; “Linking RTK activation to cell signaling”: IRS docking proteins and Figure 3A; “Mechanisms of Receptor Activation” and “TKD autoinhibition by the activation loop: insulin and FGF receptors”, Figure 2E.
Publisher: Springer.
Published in Molecular Biotechnology.
Cited passages: Taylor, Berkelman, Yadav and Hammond, Materials and Methods; Figures 2–4 and 5–7: transfer apparatus, film/imager comparison and loading normalization.
Publisher: American Physiological Society.
Published in American Journal of Physiology-Cell Physiology.
Cited passages: McDonough and others, “Consider the Loading Controls”, Figure 4: sample doubling changes claudin detection but not the actin signal; McDonough and others, “Consider the Specificity of the Antibody for the Target” and “Consider the Linearity of the Detection System”; McDonough and others, “Consider the Specificity of the Antibody for the Target”, Figure 2: positive tissue, knockout tissue and antibodies to different termini.
Publisher: National Academy of Sciences.
Published in Proceedings of the National Academy of Sciences of the United States of America.
Cited passages: Towbin, Staehelin and Gordon, pp. 4350–4352: Electrophoretic Blotting Procedures, Figure 1, Figures 2–3 and Table 1; Towbin, Staehelin and Gordon, pp. 4351–4353: Immunological Detection of Proteins on Nitrocellulose and Figure 4, including preimmune-serum controls.
Published in Evolution.
Cited passages: p. 1308, mating-preference procedure and wing-marking control; p. 1308, population origin, media and cage conditions; pp. 1309–1310, Tables 1–2 and discussion of conditioning and physical isolation.
Publisher: Taylor & Francis (identified on inspected download cover).
Published in Systematic Biology.
Cited passages: p. 880, Table 1: distinct monophyletic, genealogical and diagnosable versions of phylogenetic criteria; pp. 880–883, Table 1, Figure 1 and “Conceptualization versus Delimitation”: distinguish defining properties from operational evidence; pp. 884–885, “Alternatives to the Traditional Properties”: divergence cutoffs and geographic differentiation.
Publisher: Addgene.
Cited passages: O’Connor (2018), Plasmid features enable multiple student experiments and Complementation reveals conservation of function; O’Connor (2018), Plasmid features enable multiple student experiments and Complementation reveals conservation of function: GAL1 promoter.
Publisher: American Society for Cell Biology.
Published in CBE—Life Sciences Education 17, ar1.
Cited passages: Reeves et al. (2018), Course Activities, pp. 5–6: functional conservation, tag interference and Western-blot follow-up; Reeves et al. (2018), project design, pp. 3–4, and Course Activities, pp. 5–6; Reeves, Warner, Ludlow and O’Connor (2018), Course Activities, pp. 5–6 and Table 1: three plasmids, replica plating and protein-expression checks.
Publisher: Genetics Society of America.
Published in Genetics 197(1), 33–48.
Cited passages: Duina, Miller and Keeney (2014), introduction and Experimental Toolkit and Related Resources: manipulation of genes and phenotypic effects; Duina, Miller and Keeney (2014), introduction, Figure 2 and Experimental Toolkit and Related Resources.
Published in Nature.
Full article paywalled. No detailed sequencing methods, contamination controls, raw sequence alignments or trees claimed inspected. Article text explicitly states this access limit; not presented as a paper review. Its 1997 closest-rickettsial-relative claim and obsolete host classification are not repeated. No modern species described as literal ancestor.
On the origin of mitosing cells by Lynn Sagan by Codex 0 Created 2026-10-13 Updated 2026-10-31
Lynn Sagan is the historical byline of Lynn Margulis.
Published in Journal of Theoretical Biology.
Publisher: NobelPrize.org.
Cited passages: Nobel Assembly, Mature cells can be reprogrammed to become pluripotent, Scientific background: Gurdon nuclear transfer and distinction between differentiation and reprogramming; Nobel Assembly, Scientific background, Gurdon's nuclear-transfer experiments and serial transplantation.
Publisher: Nobel Foundation.
Cited passages: Gurdon, Nobel lecture, The Technique of Nuclear Transfer in Xenopus, p. 233: one-nucleolus diploid marker and its use to establish donor nuclear origin; Gurdon, The Egg and the Nucleus: A Battle for Supremacy, The Technique of Nuclear Transfer in Xenopus; indexed authored Nobel lecture text inspected.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact