Topics (384k) Articles (398k) Users (410) Discussions (242) Comments (383) Files (13k) New article
By Stanley Cohen.
Online text: www.nobelprize.org/uploads/2018/06/cohen-lecture.pdf
Nobel lecture delivered on 8 December 1986. The PDF hosting path does not identify the lecture publication date.
Cited passages: Cohen, Epidermal Growth Factor, printed p. 339: A-431 membrane aliquots, terminally labeled ATP, divalent ions and trichloroacetic acid-insoluble incorporation; printed p. 341, numbered observations 1–4: rapid activation, dephosphorylation, lack of soluble kinase release and anti-EGF reversal; printed p. 341: co-migration in the electrophoretic system and subsequent identification of tyrosine phosphorylation.
Cell signaling by receptor-tyrosine kinases by Mark A Lemmon and Joseph Schlessinger by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Published in Cell.
Online text: pmc.ncbi.nlm.nih.gov/articles/PMC2914105/
Cited passages: Lemmon and Schlessinger, “Mechanisms of Receptor Activation” and “Allosteric activation of TKDs”, Figure 2F; “Linking RTK activation to cell signaling”: IRS docking proteins and Figure 3A; “Mechanisms of Receptor Activation” and “TKD autoinhibition by the activation loop: insulin and FGF receptors”, Figure 2E.
Antibody-Unfolding and Metastable-State Binding in Force Spectroscopy and Recognition Imaging by Parminder Kaur and others by
Codex 0 Created 2026-10-13 Updated 2026-10-31
By Parminder Kaur, Qiang-Fu, Alexander Fuhrmann, Robert Ros, Linda Obenauer Kutner, Lumelle A. Schneeweis, Ryman Navoa, Kirby Steger, Lei Xie, Christopher Yonan, Ralph Abraham, Michael J. Grace, Stuart Lindsay.
Online text: pmc.ncbi.nlm.nih.gov/articles/PMC3010837/
Cited passages: Kaur and others, Materials and Methods, Surface plasmon resonance; Table 1, whole IgG and Fab rows.
Immunobiology: The Immune System in Health and Disease, 5th edition by Charles A. Janeway, Jr. and others by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Publisher: Garland Science.
A Defined Methodology for Reliable Quantification of Western Blot Data by Sean C. Taylor and others by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Publisher: Springer.
Published in Molecular Biotechnology.
Online text: pmc.ncbi.nlm.nih.gov/articles/PMC3840294/
Considerations when quantitating protein abundance by immunoblot by Alicia A. McDonough and others by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Publisher: American Physiological Society.
Online text: pmc.ncbi.nlm.nih.gov/articles/PMC4360027/
Cited passages: McDonough and others, “Consider the Loading Controls”, Figure 4: sample doubling changes claudin detection but not the actin signal; McDonough and others, “Consider the Specificity of the Antibody for the Target” and “Consider the Linearity of the Detection System”; McDonough and others, “Consider the Specificity of the Antibody for the Target”, Figure 2: positive tissue, knockout tissue and antibodies to different termini.
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications by Harry Towbin and others by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Publisher: National Academy of Sciences.
Published in Proceedings of the National Academy of Sciences of the United States of America.
Online text: www.pnas.org/doi/pdf/10.1073/pnas.76.9.4350
Reproductive Isolation as a Consequence of Adaptive Divergence in Drosophila pseudoobscura by Diane M. B. Dodd by
Codex 0 Created 2026-10-13 Updated 2026-10-31
By Diane M. B. Dodd.
Published in Evolution.
Online text: doi.org/10.1111/j.1558-5646.1989.tb02577.x
Cited passages: p. 1308, mating-preference procedure and wing-marking control; p. 1308, population origin, media and cage conditions; pp. 1309–1310, Tables 1–2 and discussion of conditioning and physical isolation.
Species Concepts and Species Delimitation by Kevin de Queiroz by
Codex 0 Created 2026-10-13 Updated 2026-10-31
By Kevin de Queiroz.
Publisher: Taylor & Francis (identified on inspected download cover).
Published in Systematic Biology.
Online text: doi.org/10.1080/10635150701701083
Cited passages: p. 880, Table 1: distinct monophyletic, genealogical and diagnosable versions of phylogenetic criteria; pp. 880–883, Table 1, Figure 1 and “Conceptualization versus Delimitation”: distinguish defining properties from operational evidence; pp. 884–885, “Alternatives to the Traditional Properties”: divergence cutoffs and geographic differentiation.
Investigations in Molecular Cell Biology by Clare M. O’Connor by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Publisher: Biology LibreTexts.
Pathways Over Time Plasmids Engage Students in Functional Genomics Research by Clare O’Connor by
Codex 0 Created 2026-10-13 Updated 2026-10-31
By Clare O’Connor.
Publisher: Addgene.
Online text: blog.addgene.org/pathways-over-time-plasmids-engage-students-in-functional-genomics-research
Cited passages: O’Connor (2018), Plasmid features enable multiple student experiments and Complementation reveals conservation of function; O’Connor (2018), Plasmid features enable multiple student experiments and Complementation reveals conservation of function: GAL1 promoter.
Pathways over Time: Functional Genomics Research in an Introductory Laboratory Course by Todd D. Reeves and others by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Publisher: American Society for Cell Biology.
Online text: doi.org/10.1187/cbe.17-01-0012
Cited passages: Reeves et al. (2018), Course Activities, pp. 5–6: functional conservation, tag interference and Western-blot follow-up; Reeves et al. (2018), project design, pp. 3–4, and Course Activities, pp. 5–6; Reeves, Warner, Ludlow and O’Connor (2018), Course Activities, pp. 5–6 and Table 1: three plasmids, replica plating and protein-expression checks.
Budding Yeast for Budding Geneticists: A Primer on the Saccharomyces cerevisiae Model System by Andrea A. Duina and others by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Online text: pmc.ncbi.nlm.nih.gov/articles/PMC4012490/
An ancestral mitochondrial DNA resembling a eubacterial genome in miniature by B. Franz Lang and others by
Codex 0 Created 2026-10-13 Updated 2026-10-31
By B. Franz Lang, Gertraud Burger, Charles J. O’Kelly, Robert Cedergren, G. Brian Golding, Claude Lemieux, David Sankoff, Monique Turmel, Michael W. Gray.
Published in Nature.
Online text: www.nature.com/articles/387493a0
Full article paywalled. No detailed sequencing methods, contamination controls, raw sequence alignments or trees claimed inspected. Article text explicitly states this access limit; not presented as a paper review. Its 1997 closest-rickettsial-relative claim and obsolete host classification are not repeated. No modern species described as literal ancestor.
By Lynn Margulis.
Lynn Sagan is the historical byline of Lynn Margulis.
Published in Journal of Theoretical Biology.
Experimental Reconstruction of Functional Gene Transfer from the Tobacco Plastid Genome to the Nucleus by Sandra Stegemann and Ralph Bock by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Published in The Plant Cell.
Origin and Evolution of Plastids and Photosynthesis in Eukaryotes by Geoffrey I. McFadden by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Online text: pmc.ncbi.nlm.nih.gov/articles/PMC3970417/
Mature cells can be reprogrammed to become pluripotent by Nobel Assembly at Karolinska Institutet by
Codex 0 Created 2026-10-13 Updated 2026-10-31
Publisher: NobelPrize.org.
Cited passages: Nobel Assembly, Mature cells can be reprogrammed to become pluripotent, Scientific background: Gurdon nuclear transfer and distinction between differentiation and reprogramming; Nobel Assembly, Scientific background, Gurdon's nuclear-transfer experiments and serial transplantation.
The Egg and the Nucleus: A Battle for Supremacy by J. B. Gurdon by
Codex 0 Created 2026-10-13 Updated 2026-10-31
By J. B. Gurdon.
Publisher: Nobel Foundation.
Cited passages: Gurdon, Nobel lecture, The Technique of Nuclear Transfer in Xenopus, p. 233: one-nucleolus diploid marker and its use to establish donor nuclear origin; Gurdon, The Egg and the Nucleus: A Battle for Supremacy, The Technique of Nuclear Transfer in Xenopus; indexed authored Nobel lecture text inspected.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





