KCNQ4 is a gene that encodes a potassium ion channel, which is part of the KCNQ (Kv7) family of voltage-gated potassium channels. These channels are important for the regulation of electrical activity in various tissues, particularly in the nervous system and the inner ear. KCNQ4 specifically plays a critical role in the auditory system, where it helps to control the membrane potential of hair cells in the cochlea.
Bi-isotropic materials are materials that exhibit isotropic properties in both mechanical and electromagnetic contexts. In simpler terms, these materials have the same mechanical and electromagnetic characteristics regardless of the direction in which they are measured. In mechanical terms, an isotropic material has uniform properties in all directions. This means that its mechanical response (like stress, strain, stiffness, etc.) is the same no matter the orientation of the applied forces.
KCNT2 (Potassium Channel, Subfamily T, Member 2) is a gene that encodes a protein contributing to the formation of ion channels in the cell membranes. These channels are regulated by potassium ions (K+), which are essential for a variety of physiological functions, including the regulation of cell excitability, electrical signaling in neurons, and muscle contraction.
KCNV2 is a gene that encodes a potassium voltage-gated channel subunit. Potassium channels are essential for various physiological processes, including the regulation of electrical activity in neurons and muscle cells. The KCNV2 protein is specifically involved in the formation of voltage-gated potassium channels that contribute to the repolarization phase of action potentials in excitable tissues.
P2RX7, or purinergic receptor P2X 7, is a gene that encodes a protein belonging to the P2X family of ion channels. These proteins are activated by adenosine triphosphate (ATP), a molecule that plays a critical role in energy transfer and signaling in cells.
The term "SK channel" can refer to different concepts depending on the context. Here are a few possible interpretations: 1. **SK Telecom**: In the context of telecommunications, "SK channel" might refer to channels or services provided by SK Telecom, a major South Korean telecommunications company.
Small-conductance mechanosensitive channels (also known as MscS channels) are a type of ion channel that respond to mechanical stimuli, such as changes in membrane tension. These channels are primarily found in bacteria, but similar proteins have been identified in eukaryotic cells.
TRPM2 (Transient Receptor Potential Melastatin 2) is a member of the TRP (Transient Receptor Potential) ion channel family, which is known for its role in various physiological processes, including the sensation of temperature, pain, and other stimuli.
TRPM3 (Transient Receptor Potential Melastatin 3) is a member of the transient receptor potential (TRP) channel family, which consists of ion channels that play critical roles in various physiological processes. Specifically, TRPM3 is known for its involvement in sensory transduction, particularly in the perception of pain and temperature.
TRPM5 (Transient Receptor Potential Melastatin 5) is a member of the TRP (transient receptor potential) ion channel family. It is primarily expressed in certain sensory cells, particularly those involved in taste and in the inner ear. TRPM5 is a calcium-permeable cation channel that is activated by variations in intracellular calcium levels and is known to play a significant role in signal transduction processes.
TRPP, or Transient Receptor Potential Polycystin, refers to a family of ion channels that play significant roles in various physiological processes. The two most notable members of this family are TRPP1 and TRPP2, which are integral to the function of the primary cilia in renal epithelial cells.
The Transient Receptor Potential Channel-Interacting Protein Database (TRIPDB) is a specialized database that focuses on providing information related to transient receptor potential (TRP) channels and their interacting proteins. TRP channels are a group of ion channels located in various cellular membranes and are involved in a wide range of physiological processes including sensation, temperature regulation, and pain perception.
VDAC1, or Voltage-Dependent Anion Channel 1, is a protein that is primarily located in the outer mitochondrial membrane. It plays a crucial role in the regulation of mitochondrial metabolism and cellular homeostasis. VDAC1 is involved in the transport of ions and small metabolites across the mitochondrial membrane, facilitating the exchange of molecules such as ATP, ADP, and various metabolites between the mitochondria and the cytosol.
Voltage-gated ion channels are specialized membrane proteins that open or close in response to changes in the membrane potential (voltage) of a cell. They play a crucial role in the generation and propagation of electrical signals in excitable tissues, like neurons, muscle cells, and some endocrine cells. ### Key Features: 1. **Voltage Sensitivity**: These channels have sensors that detect changes in the electrical potential across the cell membrane.
  • Elegoo Breadboard power supply module MB‐V2:
    • Input voltage: 6.5-9v (DC) via 5.5mm x 2.1mm plug
    • Output voltage: 3.3V/5v
    • Maximum output current: 700 mA
    TODO center positive or center negative?
    Does not come with AC adapter, getting this one: www.amazon.co.uk/dp/B08ZN476FW output: DC 9V 1A Power Supply Adapter, Plug 5.5mm x 2.1mm, Center Positive,B rand: Security-01, input: AC 100-240V 50/60 Hz, Cable length: 1.8m
    Parts list from the ZIP:
  • resistors:
    • 10x each:
    • 30x 220
  • 1n4007 General Purpose Rectifier
  • 22pf 104 Ceramic Capacitor
  • 4N35 optocoupler
  • 74HC595 8-bit serial-in, serial or parallel-out shift register with output latches; 3-state
  • Active buzzer
  • Buttons
  • CDS-55 Photoresistor
  • Electrolytic Capacitor
  • Focusens MF52D 103f 3950 thermistor. Beta value 25/50 Celcius: 3950. R_25: I measured 9.61 k Ohms. The number 103 they document as:
    These descriptions are weird, but ChatGPT has the theory that the first two digits are actual values, and the last is multiplier, so which makes 10k.
    but I have no idea how that maps to 10 k Ohms.
  • PN2222 General Purpose Transistor
  • Passive buzzer
  • 3386p Bourns Precision Potentiometer - 1 103T: from 0 to 10k Ohms, measured with multimeter. According to the manual the "103" mean 10 k oms, which is consistent with our measurement. "P 103" is etched into the part.
  • LEDs:
    • White LED 10x
    • Kingbright RGB LEDs 10x red, green, yellow, blue:
      • maximum Continuous Forward Current: 30 mA for read and blue, 25 mA for green
      • 303025
      • under 20 mA
      20 mA appears to be the typical operation. So with the 2.0 V drop on 5 V power we want a resistor such that:
      for the max 50 mA we would instead have 60 Ohms
The terms "waves" and "instabilities from a neutral dynamo" refer to phenomena in astrophysical and geophysical contexts, particularly in the study of magnetic fields generated by fluid motions in electrically conducting fluids like plasmas or liquid metals. ### Waves In the context of a dynamo, "waves" typically refer to oscillatory phenomena in the magnetic and flow fields.
F2 propagation refers to a type of radio wave propagation that occurs in the high-frequency (HF) band, particularly in the ionosphere. The F2 layer is the highest region of the ionosphere, typically found at altitudes between about 200 to 400 kilometers (approximately 124 to 248 miles) above the Earth's surface. It is characterized by high electron densities, which can facilitate long-distance radio communications.
Fast Atom Bombardment (FAB) is a technique used in mass spectrometry for the ionization of samples, particularly those that are non-volatile and thermally labile. Unlike traditional ionization methods, FAB allows the analysis of larger biomolecules, such as proteins, peptides, and other complex organic compounds. In the FAB process, a sample is typically dissolved in a suitable solvent and then bombarded with a beam of energetic atoms, often xenon or argon.
Laser ablation electrospray ionization (LAESI) is an advanced analytical technique used primarily in mass spectrometry for the direct analysis of materials. This method combines two powerful techniques: laser ablation and electrospray ionization, allowing for the rapid and sensitive analysis of solid and semi-solid samples.
Laser diode thermal desorption (LDTD) is a technique used primarily in analytical chemistry and mass spectrometry for the desorption and ionization of sample analytes. This method utilizes the focused energy from a laser diode to heat a sample material, causing the analytes to desorb from the surface of a solid or liquid matrix into the gas phase. ### Key Components of LDTD: 1. **Laser Diode**: A laser device that emits light at specific wavelengths.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact