C17orf75, or "Chromosome 17 Open Reading Frame 75," is a gene located on chromosome 17. It encodes a protein whose specific function is not fully understood. Like many other genes, it may play various roles in cellular processes, but detailed studies regarding its biological significance, potential associations with diseases, or mechanisms of action are still ongoing. As with many genes, research evolves, and new findings could shed light on its roles in human health or disease.
DNA barcoding in diet assessment is a molecular technique used to identify and analyze the dietary components of an organism’s diet by analyzing the DNA sequences of the consumed food items. This method provides a more accurate and sensitive means of identifying prey or food sources compared to traditional methods that often rely on morphological identification.
Canadian Bioinformatics Workshops (CBW) is an initiative aimed at providing training and resources in bioinformatics to researchers and students in Canada and beyond. These workshops typically cover a wide range of topics within the field, including but not limited to data analysis, software tools, programming languages, and various bioinformatics applications in genomics and proteomics. CBW is often organized by institutions, universities, or research groups and may feature hands-on, practical training sessions led by experts in the field.
A DNA binding site refers to a specific region on the DNA molecule where proteins, such as transcription factors, enzymes, and other regulatory proteins, attach to the DNA. These sites are typically characterized by specific nucleotide sequences that are recognized and bound by these proteins, facilitating various biological processes such as gene regulation, DNA replication, repair, and chromatin remodeling.
Direct Coupling Analysis (DCA) is a computational technique used in various fields such as biology, particularly in the analysis of protein structures and interactions, as well as in machine learning and statistics. In the context of protein science, DCA is used to identify and model the interactions between different residues in a protein sequence. The primary goal is to discern which amino acids are directly coupled to each other through evolutionary relationships.
Fish DNA barcoding is a genetic method used to identify and classify fish species based on a short, standardized region of their DNA. This technique leverages a specific gene, often a segment of the mitochondrial cytochrome c oxidase subunit I (COI) gene, to create a "bar code" unique to each species. The primary goal of fish DNA barcoding is to provide a reliable and efficient means of species identification, especially for those that might be difficult to distinguish morphologically.
Flow Cytometry Standard (FCS) is a file format specifically designed for storing the results of flow cytometry experiments. Flow cytometry is a biophysical technology used to analyze the physical and chemical characteristics of particles, typically cells, in a fluid as they pass through a laser. The FCS file format was developed to facilitate the exchange of flow cytometry data between different instruments and software.
The Foundational Model of Anatomy (FMA) is a comprehensive, detailed representation of human anatomy that provides a structured, navigable framework for understanding the relationships between anatomical structures. Developed at the University of Washington, the FMA incorporates information from various anatomical sources to create a high-quality, evolving digital resource that serves both educational and research purposes.
The GOR method, which stands for Gas-Oil Ratio method, is primarily used in petroleum engineering to evaluate reservoirs and estimate the performance of oil and gas wells. The gas-oil ratio (GOR) is defined as the volume of gas that is produced per unit of oil and is typically expressed in standard cubic feet of gas per barrel of oil (scf/bbl).
Gene Designer is a software application developed for the design and analysis of biological sequences, particularly for synthetic biology and genetic engineering. It provides tools for researchers and scientists to create, visualize, and simulate gene constructs, allowing them to design DNA sequences for various purposes, such as creating genetically modified organisms, developing gene therapies, and engineering proteins with desired properties.
Imaging cycler microscopy is a sophisticated imaging technique utilized in biological and medical research to capture high-resolution images of samples over time. This approach combines aspects of microscopy with a cyclic or repeated sequence of imaging cycles to enhance the detection and resolution of specific cellular or subcellular features. The core idea behind imaging cycler microscopy is to utilize various imaging modalities and/or conditions in a systematic manner to gather detailed information about the specimen.
The ISCB Innovator Award is presented by the International Society for Computational Biology (ISCB) to recognize individuals or teams who have made significant contributions to the field of computational biology through innovative research, methodologies, or applications. The award aims to honor groundbreaking work that has advanced the field and provided new insights into the biological sciences.
Portfolio optimization is a quantitative method used in finance to allocate assets in a way that maximizes expected returns for a given level of risk, or alternatively, minimizes risk for a desired level of expected return. The goal is to create a well-balanced portfolio that achieves the best possible outcome based on the investor's risk tolerance, investment objectives, and constraints. Key concepts in portfolio optimization include: 1. **Risk and Return**: Investors seek to maximize returns while managing risk.
Biopunk is a subgenre of science fiction that focuses on biotechnology and its impacts on society, often exploring themes related to genetic engineering, biohacking, and the ethical implications of manipulating life forms. Here’s a list of notable biopunk works across various media: ### Literature 1. **"Neuromancer" by William Gibson** - While primarily cyberpunk, it includes biopunk themes related to artificial intelligence and genetic manipulation.
Morphometrics is the quantitative study of biological shape. It involves the measurement and analysis of the forms and structures of organisms, focusing on their size, shape, and configuration. Morphometrics can be applied in various fields such as biology, anthropology, paleontology, and ecology to understand evolutionary relationships, developmental processes, and functional adaptations.
Pfam is a comprehensive database of protein families that provides information about their sequences and functional characteristics. It is widely used in bioinformatics and molecular biology for the identification of protein domains and families based on sequence alignments. Key features of Pfam include: 1. **Protein Domains**: Pfam focuses on identifying and categorizing protein domains, which are distinct and conserved parts of proteins that can evolve, function, and exist independently of the rest of the protein chain.
Shredding, in the context of genomic data, refers to the practice of disassembling or breaking down genomic data into smaller, non-identifiable components to protect individual privacy and maintain confidentiality. This approach is particularly important in genomic research where personal genetic information can be sensitive and potentially identifiable. Here are some key points about shredding genomic data: 1. **Privacy Protection**: By breaking down genomic information into smaller parts, researchers can reduce the risk of re-identifying individuals from the data.
Translatomics is a branch of molecular biology that focuses on the study of the translation phase of gene expression, specifically the process by which messenger RNA (mRNA) is translated into proteins. This field encompasses the analysis of all aspects of translation, including the roles of ribosomes, transfer RNA (tRNA), amino acids, and various translation factors. In translatomics, researchers investigate how different factors can influence translation efficiency, fidelity, and regulation.
UniFrac is a distance metric used primarily in ecology and microbiome research to compare the phylogenetic diversity of communities. It is particularly useful for analyzing microbial communities by taking into account not just the presence or absence of different species, but also their evolutionary relationships. There are two main types of UniFrac: 1. **Weighted UniFrac**: This version considers the relative abundance of each species in the community.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 3. Visual Studio Code extension installation.Figure 4. Visual Studio Code extension tree navigation.Figure 5. Web editor. You can also edit articles on the Web editor without installing anything locally.Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





