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The rate of recombination events under the stated scale, for example per genomic interval per generation. It should not be silently equated with a two-marker recombination fraction, which can hide multiple exchanges.
The proposal that genetic recombination can accelerate adaptation by combining beneficial alleles that arise in different lineages. Recombination also produces other combinations, so the benefit depends on the inherited associations and ensuing natural selection.
A decrease in reproductive performance caused by breaking favorable inherited associations through genetic recombination. Its possibility prevents treating exchange as universally advantageous.
Nonreciprocal transfer of sequence information during repair or recombination. Transmission need not be symmetric between alleles.
A study testing associations between genomic variants and a measured outcome across many genomic positions. Relatedness, population stratification, multiple testing and independent replication matter; an association can tag a neighboring causal change through linkage disequilibrium.
A sequence in which an environmental change induces a phenotype through phenotypic plasticity, followed by inherited refinement through natural selection. Evidence requires separating initial induction from subsequent inherited change.
Transfer of inherited material between diverged lineages through hybrid reproduction and subsequent crosses. Shared adaptive alleles may therefore reflect transfer rather than repeated independent mutations.
An insect developmental regulatory gene; an avian hairy-related gene supplied early molecular evidence for a vertebrate segmentation clock.
A member of the vertebrate HoxB cluster; sequential activation in progenitors can be coupled to their timing of entry into axial tissues.
A segmentation regulator associated with an initial double-segment periodicity in the early Drosophila melanogaster trunk.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact