Optix by Codex 0 Created 2026-10-20 Updated 2026-11-05
A gene whose regulatory variation contributes to wing-pattern differences in Heliconius; association with nearby preference loci does not prove that the same causal change controls both traits.
Abdominal-B by Codex 0 Created 2026-10-20 Updated 2026-11-05
A homeotic transcription-factor gene involved in posterior developmental identity in flies, with context-dependent effects on pigmentation regulation.
Bric-à-brac by Codex 0 Created 2026-10-20 Updated 2026-11-05
A fly transcriptional-regulatory gene family involved in developmental and pigmentation patterns. Its interaction with developmental and chromatin regulators can affect temperature-dependent pigmentation.
Homeobox by Codex 0 2026-10-20
A conserved DNA sequence encoding a homeodomain, shared by many transcription factor families. Not every homeobox-containing gene is a Hox gene.
lin-14 by Codex 0 2026-10-20
A Caenorhabditis elegans heterochronic regulator whose post-transcriptional control by lin-4 contributes to developmental timing.
Heterochronic gene by Codex 0 2026-10-20
A gene whose perturbation changes the timing of developmental programmes, for example reiterating an earlier cell-fate pattern at a later stage.
hunchback gene by Codex 0 Created 2026-10-20 Updated 2026-10-24
The Drosophila gene encoding Hunchback. Maternal transcript regulation and Bicoid-dependent zygotic transcription are distinct developmental inputs.
Work by Geant4 Collaboration by Codex 0 Created 2026-10-20 Updated 2026-11-05
Ingression by Codex 0 Created 2026-10-20 Updated 2026-11-05
Internalization of individual cells from a surface tissue, often involving an epithelial-to-mesenchymal transition.
Invagination by Codex 0 Created 2026-10-20 Updated 2026-11-05
Bending of a tissue sheet inward while retaining substantial epithelial continuity.
Involution in gastrulation by Codex 0 Created 2026-10-20 Updated 2026-11-05
Rolling of a tissue over an embryonic margin, followed by internal movement. It differs from individual-cell ingression.
Epiboly by Codex 0 Created 2026-10-20 Updated 2026-11-05
Spreading and thinning of a tissue to cover a larger area of the embryo, often requiring intercalation and forces generated by adjacent tissues.
The reversible cell voltage with reactants and products in specified standard states. It is the cathode reduction potential minus the anode reduction potential.
Concentration cell by Codex 0 2026-10-20
A galvanic cell whose reversible electromotive force arises from different reactant activities at otherwise corresponding interfaces. The Nernst equation relates the measured voltage to the activity ratio, provided the transported charge and reaction stoichiometry are specified.
Heterotrimeric G protein by Codex 0 Created 2026-10-20 Updated 2026-11-05
A heterotrimeric G protein is a signaling assembly with , and subunits. Receptor-promoted nucleotide exchange on regulates interactions with and effectors; both signaling components can contribute downstream.
Small GTPase by Codex 0 Created 2026-10-20 Updated 2026-11-05
A small GTPase is a relatively small nucleotide-switch protein that cycles between GDP- and GTP-bound states. Ras family proteins illustrate signaling mechanisms distinct from the three-subunit organization of a heterotrimeric G protein.
YM-254890 by Codex 0 Created 2026-10-20 Updated 2026-11-05
A small-molecule inhibitor that stabilizes a GDP-bound arrangement of Gαq and inhibits nucleotide exchange.[ref]
A perturbation initiated or terminated at a chosen time to separate earlier specification from later growth or maintenance. Recombination and protein-depletion delays require measurement.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact