Topics (384k) Articles (398k) Users (410) Discussions (242) Comments (383) Files (13k) New article
Tetrahydrofuran is a cyclic ether solvent. Its oxygen can coordinate lithium ions and alter the aggregation of organolithium reagents.
An organolithium reagent contains a carbon–lithium interaction with substantial carbanionic carbon reactivity. Such reagents can act as bases or nucleophiles, and their solution aggregation affects both roles.
Hexamethylphosphoramide has a strongly donating phosphoryl oxygen that coordinates lithium. It changes ion pairing and aggregate structures, often increasing the reactivity of anionic oxygen donors. It does not universally produce free monomeric anions.
Dimethyl sulfoxide is a polar aprotic solvent. It supports reactions of anions with many organic electrophiles without providing an O–H proton.
Triflic anhydride is , an electrophilic sulfonylating reagent. carbonyl oxygen attack can form an O-triflylated intermediate; adjacent nitrogen donation gives an imidoyl-triflate description.
Nitrobenzene is benzene bearing a nitro group. The nitro group withdraws electron density and stabilizes certain anionic aromatic addition intermediates.
An allenyl phosphine oxide contains an allene attached to a phosphine-oxide group. Attack at the central allene carbon can generate a carbanion on the adjacent phosphorus-bearing carbon, which is stabilized by the phosphoryl substituent.
Metachloroperbenzoic acid is a peroxycarboxylic acid used for concerted oxygen transfer to alkenes. A neighboring allylic hydroxyl can direct its approach through hydrogen bonding.
Osmium tetroxide adds to an alkene to form a cyclic osmate ester. Hydrolysis releases a vicinal diol; regeneration of Os(VIII) requires a reoxidant in a catalytic cycle.
Red-Al is sodium bis(2-methoxyethoxy)aluminium hydride. Suitable propargylic alcohols undergo oxygen-directed trans hydroalumination to cyclic alkenyl aluminate species; aqueous workup gives E allylic alcohols.
An alkenyl aluminate has an anionic aluminium-containing unit attached to an alkene carbon. Intramolecular oxygen coordination can close a five-membered ring in directed propargylic alcohol reductions.
An acyl chloride contains . Addition of a nucleophile and chloride elimination is a common substitution pathway.
A nitrogen-containing aromatic scaffold; redox-active derivatives produced by bacteria can affect ecological interactions and electron transfer.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact