Publisher: American Society for Clinical Investigation.
Published in Journal of Clinical Investigation 67(2), 467-475.
Cited passages: Abstract, first through fourth paragraphs: human properitoneal preparations, radioligand binding, biochemical readouts; yohimbine versus prazosin comparisons; Abstract, second paragraph: positive beta-receptor coupling to adenylyl cyclase; Abstract: epinephrine-stimulated glycerol release as an index of lipolysis; Abstract: opposing beta and alpha-2 coupling; separate alpha-1 phospholipid response.
Publisher: National Library of Medicine.
This source is credited to an organization.
Cited passages: Epinephrine, D004837: Scope Note, entry term Adrenaline and Catecholamines tree placement.
MeSH 2026 descriptor D004837. This is a controlled-vocabulary record, not the discovery date of the substance.
Adrenal Gland by National Cancer Institute by Codex 0 Created 2026-10-14 Updated 2026-10-31
This source is credited to an organization.
Cited passages: Hormones of the Adrenal Medulla: secretion in response to sympathetic stimulation.
Cell-free fermentation by Eduard Buchner by Codex 0 Created 2026-10-14 Updated 2026-10-31
Cited passages: Cell-free fermentation, Nobel lecture delivered 11 December 1907, printed pp. 110–112, Figures 2–4 and accompanying preparation/readout text; Printed p. 115: unsuccessful zymase separation; pp. 117–118: gelatine-filter fractions and restored activity on reunion; Printed pp. 112–114: residual-cell objection, biscuit-porcelain filtration, toluene comparison and extract activity.
Publisher: NobelPrize.org.
This source is credited to an organization.
Cited passages: 13 October 1993 announcement, award citation and introductory account of PCR first presented in 1985.
Publisher: Cold Spring Harbor Laboratory.
This source is credited to an organization.
The inspected instructor manual carries copyright 2006; this is not a separately verified publication date.
Cited passages: printed pp. 18 and 29, Results and Discussion and Amplify DNA by PCR: primer dimer and nonspecific priming.
Publisher: Cold Spring Harbor Laboratory.
This source is credited to an organization.
Cited passages: p. 1, Introduction: primer-flanked insertion and stated 715/415 bp genotype patterns; pp. 2–3, Procedures I–III: extraction, 25 microlitre reaction, cycle profile, gel and UV readout.
This source is credited to an organization.
Cited passages: FAQ: primer structures as DNA-polymerase substrates, and carryover PCR-product contamination.
How to Design a Primer by Addgene by Codex 0 Created 2026-10-14 Updated 2026-10-31
Publisher: Addgene.
This source is credited to an organization.
Cited passages: Primer Design for PCR: specificity, paired melting temperatures and complementary primer sequences.
This source is credited to an organization.
Cited passages: PCR cycle number determination and Figure 7: lowered efficiency and plateau from reaction-component depletion and by-products.
Additional cited passages: Template DNA denaturation assessment, paragraphs 1 and 3–6; DNA denaturation considerations, paragraph 1; Primer annealing optimization, opening, calculated-setting and nonspecific-product paragraphs; Primer extension considerations, paragraphs 1 and 3. No human byline or publication or revision date was verified.
Principles of PCR by Thermo Fisher Scientific by Codex 0 Created 2026-10-14 Updated 2026-10-31
This source is credited to an organization.
Cited passages: Principles of PCR, accompanying description: denaturation, annealing, primer-dependent extension and dNTP incorporation.
Additional cited passages: accompanying Description, first three paragraphs, strand separation, complementary primer binding, enzyme-dependent extension temperature, dNTP incorporation and two-step cycling. Accompanying text was inspected; frame-by-frame video viewing is not asserted. No human byline or publication or revision date was verified.
Polymerase Chain Reaction (PCR) by Addgene by Codex 0 Created 2026-10-14 Updated 2026-10-31
Publisher: Addgene.
This source is credited to an organization.
Cited passages: Background Information: two primers, template-directed copying and product verification; Basic PCR Program, steps 1–6; Materials List: Taq buffer with magnesium chloride.
Additional cited passages: Background Information; Basic PCR Program, steps 1–6; Procedure, Primer Design and PCR step 13, gel readout. Basic PCR Program and Procedure give different extension durations; no unified duration is attributed to the source. No human byline or publication or revision date was verified.
Osmosis, Cell Membranes-Structure and Transport, BYU-Idaho by Codex 0 Created 2026-10-14 Updated 2026-10-31
Publisher: Brigham Young University-Idaho.
Cited passages: Cell Membranes—Structure and Transport, Osmosis: paragraphs beginning Earlier this semester and Osmolarity is a useful term; total particle counting; Cell Membranes—Structure and Transport, Osmosis: paragraphs beginning Here is another way and final Note; permeating solutes and transient effects.
Publisher: University of Toronto Department of Physics.
This source is credited to an organization.
Cited passages: Osmosis (Brine), Description steps 1–14, water-filled comparison and Old Description A.2: apparatus, readout and leak check.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact